Uncoupling protein 2 (UCP2) lowers alcohol sensitivity and pain threshold

Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia

1997 • 1,647 citations

Promoter traps in embryonic stem cells: a genetic screen to identify and mutate developmental genes in mice.

1991 • 1,358 citations

Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production

2000 • 1,068 citations

Uncoupling Protein-2 Negatively Regulates Insulin Secretion and Is a Major Link between Obesity, β Cell Dysfunction, and Type 2 Diabetes

2001 • 916 citations

Energy Metabolism in Uncoupling Protein 3 Gene Knockout Mice

2000 • 679 citations

Mice overexpressing human uncoupling protein-3 in skeletal muscle are hyperphagic and lean

2000 • 615 citations

Lack of Obesity and Normal Response to Fasting and Thyroid Hormone in Mice Lacking Uncoupling Protein-3

2000 • 391 citations

Hepatotoxicity due to mitochondrial dysfunction.

1999 • 260 citations

Antibodies Specific for GABA_A Receptor α Subunits Reveal that Chronic Alcohol Treatment Down‐Regulates α‐Subunit Expression in Rat Brain Regions

1993 • 179 citations

Brain Uncoupling Protein 2: Uncoupled Neuronal Mitochondria Predict Thermal Synapses in Homeostatic Centers

1999 • 177 citations

IMPLICATIONS OF ENDOGENOUS OPIOIDS AND DOPAMINE IN ALCOHOLISM: HUMAN AND BASIC SCIENCE STUDIES

1996 • 171 citations

Pain Genes?: Natural Variation and Transgenic Mutants

2000 • 164 citations

Alcohol Withdrawal in the Surgical Patient

1999 • 150 citations

Alcohol Withdrawal in the Surgical Patient

1999 • 119 citations

Alcohol tolerance

1986 • 82 citations

A Preliminary Study of Acute Responses to Clamped Alcohol Concentration and Family History of Alcoholism

1999 • 68 citations

Influence of Family Alcoholism History on Alcohol Metabolism, Sensitivity, and Tolerance

1987 • 54 citations

Mitochondrial Uncoupling Protein 2 (UCP2) in the Nonhuman Primate Brain and Pituitary**This work was supported by NSF Grant IBN-9728581, NIH Grants NS-36111, MH-59847, RR-00163, HD-29186, and HD-37186.

2000 • 48 citations

Regulation of GABAA Receptor Structure and Function by Chronic Drug Treatments In Vivo and with Stably Transfected Cells

1996 • 40 citations

Distinct Regulation of Brain Mitochondrial Carrier Protein-1 and Uncoupling Protein-2 Genes in the Rat Brain during Cold Exposure and Aging

2000 • 39 citations

Effects of 2-G exposure on temperature regulation, circadian rhythms, and adiposity in UCP2/3 transgenic mice

2000 • 36 citations

Development of Tolerance to and Physical Dependence on Ethanol: Daily Versus Repeated Cycles Treatment with Ethanol

1991 • 32 citations

Phenotypic and Genotypic Relationships Between Ethanol Tolerance and Sensitivity in Mice Selectively Bred for Initial Sensitivity to Ethanol (SS and LS) or Development of Acute Tolerance (HAFT and LAFT)

2000 • 31 citations

Alcohol-treatment programmes are comparable

1997 • 6 citations