Redefining interferon: the interferon-like antiviral effects of certain cytokines (interleukin-1, interferon-β2, interferon-γ) may be indirect or side effects

Virus interference. I. The interferon

1957 • 3,331 citations

Complementary DNA for a novel human interleukin (BSF-2) that induces B lymphocytes to produce immunoglobulin

1986 • 2,137 citations

Identification of interferon-gamma as the lymphokine that activates human macrophage oxidative metabolism and antimicrobial activity.

1983 • 1,918 citations

Interleukin-1

1984 • 1,625 citations

Mechanism of a Reaction in Vitro Associated with Delayed-Type Hypersensitivity

1966 • 1,604 citations

Interferon-Like Virus-Inhibitor Induced in Human Leukocytes by Phytohemagglutinin

1965 • 710 citations

Expression of human immune interferon cDNA in E. coli and monkey cells

1982 • 703 citations

Identification of the human 26-kD protein, interferon beta 2 (IFN-beta 2), as a B cell hybridoma/plasmacytoma growth factor induced by interleukin 1 and tumor necrosis factor.

1987 • 690 citations

Purification to homogeneity and characterization of human B-cell differentiation factor (BCDF or BSFp-2).

1985 • 679 citations

Recombinant interferon-gamma increases HLA-DR synthesis and expression.

1983 • 577 citations

Evidence that types I and II interferons have different receptors

1981 • 511 citations

Structure and expression of cDNA and genes for human interferon-beta-2, a distinct species inducible by growth-stimulatory cytokines.

1986 • 505 citations

Regulation of murine macrophage Ia antigen expression by a lymphokine with immune interferon activity.

1982 • 481 citations

Interleukin 1 stimulates fibroblasts to produce granulocyte-macrophage colony-stimulating activity and prostaglandin E2.

1986 • 458 citations

Cloning and expression of murine immune interferon cDNA.

1983 • 455 citations

The biology of the interferon system 1984

1985 • 413 citations

Production and Properties of Migration Inhibitory Factor and Interferon in the Circulation of Mice with Delayed Hypersensitivity

1973 • 303 citations

Characterization of the Effects of Endotoxin on Macrophage Tumor Cell Killing

1978 • 298 citations

High-affinity binding of 125I-labelled mouse interferon to a specific cell surface receptor

1980 • 275 citations

Homogeneous interferon-inducing 22K factor is related to endogenous pyrogen and interleukin-1

1985 • 236 citations

Macrophage-activating factor produced by a T cell hybridoma: physiochemical and biosynthetic resemblance to gamma-interferon.

1983 • 236 citations

A unique set of polypeptides is induced by γ interferon in addition to those induced in common with α and β interferons

1983 • 234 citations

B cell growth modulating and differentiating activity of recombinant human 26-kd protein (BSF-2, HuIFN-beta 2, HPGF).

1987 • 220 citations

Interferons and Interferon Inducers

1973 • 211 citations

Human β ₂ Interferon and B-Cell Differentiation Factor BSF-2 Are Identical

1987 • 204 citations

Enhancement of Phagocytosis by Interferon-Containing Preparations

1971 • 201 citations

Heterogeneity of poly(I).poly(C)-induced human fibroblast interferon mRNA species

1980 • 199 citations

Interleukin 1 and poly(rI) · poly(rC) induce production of a hybridoma growth factor by human fibroblasts

1987 • 181 citations

Human immune interferon gene is located on chromosome 12.

1983 • 173 citations

Induction of a 26-kDa-protein mRNA in human cells treated with an interleukin-1-related, leukocyte-derived factor

1985 • 172 citations

Specific binding of 125I-human interferon-gamma to high affinity receptors on human fibroblasts.

1982 • 165 citations

Interferon nomenclature

1980 • 157 citations

Comparative effects of various classes of mouse interferons on macrophage activation for tumor cell killing.

1985 • 151 citations

Interleukin-1 (22-K factor) induces release of granulocyte-macrophage colony-stimulating activity from human mononuclear phagocytes

1986 • 146 citations

The role of interferon-beta 1 and the 26-kDa protein (interferon-beta 2) as mediators of the antiviral effect of interleukin 1 and tumor necrosis factor.

1987 • 143 citations

Secretory proteins induced in human fibroblasts under conditions used for the production of interferon beta.

1982 • 125 citations

Mononuclear phagocytes : characteristics, physiology, and function

1985 • 117 citations

Interferons as modulators of human monocyte-macrophage differentiation. I. Interferon-gamma increases HLA-DR expression and inhibits phagocytosis of zymosan.

1984 • 106 citations

Augmentation of human monocyte-mediated cytolysis by interferon

1980 • 105 citations

Some Properties of Virus and Immune-Induced Human Lymphocyte Interferons

1972 • 103 citations

Functional and morphologic characteristics of interferon-treated macrophages

1978 • 88 citations

An interference phenomenon in relation to yellow fever and other viruses

1937 • 78 citations

Immune and virus-induced interferons may activate cells by different derepressional mechanisms

1980 • 77 citations

Interferon β2 as a promoter of growth and differentiation of B cells

1987 • 74 citations

Sequence and structural homologies among type I and type II interferons

1982 • 58 citations

Interferon-γ is required in activation of macrophages for tumor cytotoxicity

1983 • 53 citations

Inferferon induced in human leukocytes by concanavalin A: isolation and characterization of γ‐ and β‐type components

1981 • 51 citations

Identification of the Translation Products of Human Fibroblast Interferon mRNA in Reticulocyte Lysates

1979 • 47 citations

Interferon‐induced enhancement of macrophage‐mediated tumor cytolysis and its difference from activation by lymphokines

1981 • 45 citations

Stimulation of Fibroblast Interferon Production by a 22K Protein from Human Leukocytes

1985 • 40 citations

Lymphokine-mediated activation of human monocytes: Neutralization by monoclonal antibody to interferon-γ

1984 • 40 citations

Mouse immune interferon (IFN-?) gene is on chromosome 10

1984 • 35 citations

Induction and regulation of the 26-kDa protein in the absence of synthesis of beta-interferon mRNA in human cells

1984 • 31 citations

The interferon genes

1982 • 27 citations

The chromosomal location of mouse interferon alpha genes.

1984 • 24 citations

EFFECT OF HUMAN LEUKOCYTE INTERFERON ON PHAGOCYTIC ACTIVITY OF POLYMORPHONUCLEAR LEUKOCYTES

1982 • 19 citations

An Interferon-beta-like or Interferon-inducing Protein Released by Mitogen-stimulated Human Leukocytes

1983 • 17 citations

A large component of the antiviral activity of mouse interferon-gamma may be due to its induction of interferon-alpha.

1987 • 15 citations

Draft proposals for interleukin nomenclature

1986 • 13 citations

Western Europe: Research and Development

1963 • 6 citations

Molecular characterization of macrophage activating factor for tumor cytotoxicity

1985 • 3 citations

Interaction of macrophages and intra-erythrocytic malaria parasites

1985 • 1 citations