Reperfusion after Thrombolytic Therapy of Embolic Stroke in the Rat: Magnetic Resonance and Biochemical Imaging

Tissue Plasminogen Activator for Acute Ischemic Stroke

1995 • 10,997 citations

Spin Diffusion Measurements: Spin Echoes in the Presence of a Time-Dependent Field Gradient

1965 • 7,940 citations

A Semiautomated Method for Measuring Brain Infarct Volume

1990 • 1,610 citations

Perfusion imaging

1992 • 1,497 citations

Experimental studies of ischemic brain edema

1986 • 932 citations

Insulin effects on monovalent cation transport and Na-K-ATPase activity

1978 • 692 citations

Continuous Measurement of Cerebral Cortical Blood Flow by Laser—Doppler Flowmetry in a Rat Stroke Model

1989 • 480 citations

Temporal thresholds for neocortical infarction in rats subjected to reversible focal cerebral ischemia.

1991 • 325 citations

Evolution of Regional Changes in Apparent Diffusion Coefficient during Focal Ischemia of Rat Brain: The Relationship of Quantitative Diffusion NMR Imaging to Reduction in Cerebral Blood Flow and Metabolic Disturbances

1995 • 301 citations

Induction of DNA Fragmentation After 10 to 120 Minutes of Focal Cerebral Ischemia in Rats

1995 • 276 citations

Relationship between diffusion-weighted MR images, cerebral blood flow, and energy state in experimental brain infarction

1995 • 237 citations

Studies on the Specific Fibrinolytic Effect of Human Extrinsic (Tissue-Type) Plasminogen Activator in Human Blood and in Various Animal Species in Vitro

1981 • 231 citations

Local intraarterial fibrinolysis in the carotid territory.

1989 • 189 citations

A pictorial representation of endogenous brain ATP by a bioluminescent method

1978 • 154 citations

Neutrophil inhibitory factor is neuroprotective after focal Ischemia in rats

1995 • 150 citations

Pharmacokinetics and systemic fibrinogenolytic effects of recombinant human tissue-type plasminogen activator (rt-PA) in humans.

1985 • 149 citations

Improved model of thromboembolic stroke and rt-PA induced reperfusion in the rat

1997 • 130 citations

Activity of coagulation and fibrinolysis parameters in animals.

1994 • 121 citations

A Rat Model of Reproducible Cerebral Infarction Using Thrombotic Blood Clot Emboli

1992 • 115 citations

A “radical” view of cerebral ischemic injury

1994 • 114 citations

A topographic quantitative method for measuring brain tissue pH under physiological and pathophysiological conditions

1983 • 108 citations

Transgenic Mice and Knockout Mutants in the Study of Oxidative Stress in Brain Injury

1995 • 106 citations

A Bioluminescence Method for the Demonstration of Regional Glucose Distribution in Brain Slices

1981 • 99 citations

Recombinant human tissue-type plasminogen activator therapy in acute thromboembolic stroke

1987 • 96 citations

Evolution of Photochemically Induced Focal Cerebral Ischemia in the Rat

1996 • 79 citations

Imaging of the apparent diffusion coefficient for the evaluation of cerebral metabolic recovery after cardiac arrest

1995 • 49 citations

Local hemodynamic changes during transient middle cerebral artery occlusion and recirculation in the rat: a [14C]iodoantipyrine autoradiographic study

1995 • 49 citations

Brain Capillary Tissue Plasminogen Activator in a Diabetes Stroke Model

1996 • 48 citations

Correction of Gradient Crosstalk and Optimization of Measurement Parameters in Diffusion MR Imaging

1995 • 47 citations

Thrombolysis with recombinant tissue plasminogen activator in acute ischemic stroke: evaluation with rCBF-SPECT

1991 • 46 citations

The safety and angiographic efficacy of tissue plasminogen activator in a cerebral embolization model

1988 • 43 citations

Cerebral Microembolization

1978 • 41 citations

Risk factors for cerebrovascular disease and the role of coagulation and fibrinolysis

1995 • 40 citations

Blood-Brain Barrier Disturbances After rt-PA Treatment of Thromboembolic Stroke in the Rat

1997 • 38 citations

Interrelationship between coagulant activity and tissue‐type plasminogen activator (t‐PA) system in acute ischaemic heart disease. Possible role of the endothelium

1990 • 36 citations

Diffusion-weighted MR imaging of experimental brain tumors in rats

1995 • 34 citations

Delayed Tissue-Plasminogen Activator Therapy in a Rabbit Model of Thromboembolic Stroke

1995 • 24 citations

Bioluminescence and fluoroscopic imaging of tissue pH and metabolites in experimental brain tumors of cat

1992 • 21 citations

Fibrinolysis in patients with acute ischaemic heart disease. With particular reference to systemic effects of tissue-type plasminogen activator treatment on fibrinolysis, coagulation and complement pathways.

1993 • 18 citations

The effects of a new tissue plasminogen activator analogue, Fb‐Fb‐CF, on cerebral reperfusion in a rabbit embolic stroke model

1989 • 15 citations

Haemostatic Functions of the Blood-Brain Barrier: Possible Implications in the Pathogenesis of Stroke

1995 • 12 citations

31P spectroscopy in thrombolytic treatment of experimental cerebral infarct

1989 • 9 citations

Beyond Thrombolysis: Other Effects of Thrombolytic Drugs

1994 • 3 citations