A comparative study of drug metabolism in the isolated perfused liver and in vivo in rats

Pharmacological implications of microsomal enzyme induction.

1967 • 2,883 citations

THE DOMINANT ROLE OF THE LIVER IN PLASMA PROTEIN SYNTHESIS

1951 • 806 citations

THE ESTIMATION OF ANTIPYRINE IN BIOLOGICAL MATERIALS

1949 • 411 citations

Steady-state plasma levels of nortriptyline in twins: Influence of genetic factors and drug therapy

1969 • 361 citations

Principles of Drug Action.

1969 • 316 citations

Liver Circulation and Function

1963 • 312 citations

Electron microscopic and biochemical study of lipoprotein synthesis in the isolated perfused rat liver

1967 • 243 citations

Application of isotope derivative technique to assay of secondary amines: estimation of desipramine by acetylation with H3-acetic anhydride.

1967 • 123 citations

Studies on the mechanism of phenobarbital-enhanced sulfobromophthalein disappearance.

1968 • 109 citations

Dose-dependence of drug plasma level decline in dogs.

1967 • 98 citations

Regulation of Gluconeogenesis by Fatty Acid Oxidation in Isolated Perfused Livers of Non-Starved Rats

1968 • 89 citations

A New Approach to Acid-Base Metabolism

1961 • 84 citations

The effect of desmethylimipramine and other “anti-tremorine” drugs on the metabolism of tremorine and oxotremorine in rats and mice

1968 • 35 citations

Über den Stoffwechsel des Butazolidin

1959 • 19 citations

Drug metabolism in hypothermia. Uptake, metabolism and excretion of C14-procaine by the isolated, perfused rat liver.

1968 • 15 citations

Action of amobarbital on microsomal and mitochondrial respiratory state in perfused rat liver with and without phenobarbital induction

1969 • 13 citations

Inhibition of drug metabolism. VI. Inhibition of hexobarbital metabolism in the isolated perfused liver of the rat.

1968 • 12 citations

Synthesis of tritiated oxotremorine, labelled in the pyrrolidine ring.

1966 • 4 citations