2,4,5- triarylimidazole inhibitors of IL-1 biosynthesis

A protein kinase involved in the regulation of inflammatory cytokine biosynthesis

1994 • 3,285 citations

N-methoxy-n-methylamides as effective acylating agents

1981 • 1,731 citations

Blocking IL-1: interleukin 1 receptor antagonist in vivo and in vitro

1991 • 729 citations

Interleukin 6 is involved in interleukin 1‐induced activities

1988 • 422 citations

Release of tumor necrosis factor-alpha from macrophages. Enhancement and suppression are dose-dependently regulated by prostaglandin E2 and cyclic nucleotides.

1988 • 397 citations

Bicyclic Imidazoles as a Novel Class of Cytokine Biosynthesis Inhibitors

1993 • 146 citations

Interleukin 1: more than a mediator between leukocytes

1988 • 120 citations

Specific bioactivities of monocyte-derived interleukin 1 alpha and interleukin 1 beta are similar to each other on cultured murine thymocytes and on cultured human connective tissue cells.

1986 • 82 citations

Purification to homogeneity and amino acid sequence analysis of two anionic species of human interleukin 1.

1986 • 73 citations

Inhibition of monocyte IL-1 production by the anti-inflammatory compound, SK&F 86002

1988 • 71 citations

Antiinflammatory activity of 5,6-diaryl-2,3-dihydroimidazo[2,1-b]thiazoles. Isomeric 4-pyridyl and 4-substituted-phenyl derivatives

1984 • 65 citations

Inhibition of interleukin 1 synthesis by tenidap: A new drug for arthritis

1991 • 56 citations

Interleukin‐1 in the pathogenesis of fever

1987 • 43 citations

Inhibition of interleukin-1 release by IX 207-887

1990 • 18 citations

Use of a continous assay of oxygen consumption to evaluate the pharmacology of 5-lipoxygenase inhibitors

1993 • 10 citations

Inhibitory effect of SK&F 86002 on monocyte IL-1 production

1989 • 9 citations