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Cytogenetics, FISH and RT-PCR Analysis of Acute Promyelocytic Leukemia: Structure of the Fusion Point in a Case Lacking Classic t(15;17) Translocation

Data up to Jan 2025

Published2002
Citations9
References12

Total Citations Per Year

Abstract

References (12)

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

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The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

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Characterization of acute promyelocytic leukemia cases lacking the classic t(15;17): results of the European Working Party

2000 • 320 citations

Genomic variability and alternative splicing generate multiple PML/RAR alpha transcripts that encode aberrant PML proteins and PML/RAR alpha isoforms in acute promyelocytic leukaemia.

1992 • 277 citations

Molecular monitoring of the myl/retinoic acid receptor-alpha fusion gene in acute promyelocytic leukemia by polymerase chain reaction

1992 • 173 citations

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2000 • 165 citations

Association of PML-RARα Fusion mRNA Type With Pretreatment Hematologic Characteristics But Not Treatment Outcome in Acute Promyelocytic Leukemia: An Intergroup Molecular Study

1997 • 123 citations

Catalog of chromosome aberrations in cancer, 4th ed

1992 • 87 citations

Interstitial insertion of retinoic acid receptor-alpha gene in acute promyelocytic leukemia with normal chromosomes 15 and 17

1994 • 83 citations

Isoforms of PML-retinoic acid receptor alpha fused transcripts affect neither clinical features of acute promyelocytic leukemia nor prognosis after treatment with all-trans retinoic acid. The Leukemia Study Group of the Ministry of Health and Welfare (Kohseisho).

1995 • 55 citations

PML/RAR‐α rearrangement in acute promyelocytic leukaemias apparently lacking the t(15;17) translocation

1992 • 50 citations

Rejoining between 9q+ and Philadelphia chromosomes results in normal-looking chromosomes 9 and 22 in Ph1-negative chronic myelocytic leukemia

1989 • 36 citations

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Cytogenetics, FISH and RT-PCR Analysis of Acute Promyelocytic Leukemia: Structure of the… (2002) – Leukemia & lymphoma/Leukemia and lymphoma | Metascience Observatory Explorer