Reconstitution of a functional acetylcholine regulator under defined conditions

Structural and Functional Properties of the Acetylcholine Receptor Protein in its Purified and Membrane-Bound States

1978 • 399 citations

Large‐Scale Purification of the Acetylcholine‐Receptor Protein in Its Membrane‐Bound and Detergent‐Extracted Forms from Torpedo marmorata Electric Organ

1977 • 375 citations

Acetylcholine and local anesthetic binding to Torpedo nicotinic postsynaptic membranes after removal of nonreceptor peptides.

1979 • 350 citations

In Vitro excitation of purified membrane fragments by cholinergic agonists

1971 • 250 citations

Fast Kinetic Studies on the Interaction of a Fluorescent Agonist with the Membrane‐Bound Acetylcholine Receptor from Torpedo marmorata

1979 • 183 citations

Reconstitution of carbamylcholine-dependent sodium ion flux and desensitization of the acetylcholine receptor from Torpedo californica.

1978 • 176 citations

Distinct protein components from Torpedo marmorata membranes carry the acetylcholine receptor site and the binding site for local anesthetics and histrionicotoxin.

1978 • 150 citations

Facets of the Structures of Acetylcholine Receptors from Electrophorus and Torpedo

1976 • 142 citations

Membranes Rich in Acetylcholine Receptor: Characterization and Reconstitution to Excitable Membranes from Exogenous Lipids

1978 • 132 citations

Identification of a local anesthetic binding site in nicotinic post-synaptic membranes isolated from Torpedo marmorata electric tissue.

1979 • 120 citations

Fast Kinetic Studies on the Allosteric Interactions between Acetylcholine Receptor and Local Anesthetic Binding Sites

1979 • 102 citations

Studies on the electrogenic action of acetylcholine with Torpedo marmorata electric organ

1976 • 101 citations

Molecular Specialization and Symmetry in Membrane Function

1978 • 100 citations

Reconstitution of a Chemically Excitable Membrane

1974 • 87 citations

Interconversion between Different States of Affinity for Acetylcholine of the Cholinergic Receptor Protein from Torpedo marmorata

1975 • 87 citations

Purified Acetylcholine Receptor: Its Reconstitution to a Chemically Excitable Membrane

1974 • 83 citations

Genetic dissection of short-term and long-term facilitation at the Drosophila neuromuscular junction.

1978 • 73 citations

The amino‐terminal sequence of the 40 000 molecular weight subunit of the acetylcholine receptor protein from Torpedo marmorata

1979 • 58 citations

Recovery of Some Functional Properties of the Detergent-Extracted Cholinergic Receptor Protein from Torpedo marmorata after Reintegration into a Membrane Environment

1978 • 54 citations

Synthesis of fluorescent acyl‐cholines with agonistic properties: pharmacological activity on Electrophorus electroplaque and interaction in vitro with Torpedo receptor‐rich membrane fragments

1976 • 47 citations

Isolation and Purification of the Nicotinic Acetylcholine Receptor and Its Functional Reconstitution into a Membrane Environment

1977 • 37 citations

Identification of the polypeptide chains in Torpedo californica electroplax membranes that interact with a local anesthetic analog.

1979 • 31 citations

Recovery of allosteric interactions between a fluorescent cholinergic agonist and local anesthetics after removal of the detergent from cholate‐solubilized membrane fragments rich in acetylcholine receptor

1978 • 18 citations

5. Ligand-Binding Properties of Membrane-Bound Cholinergic Receptors of Torpedo Mormorata

1978 • 5 citations