Pain-signalling systems in the dorsal and ventral spinal cord

Pain Mechanisms: A New Theory

1965 • 10,272 citations

The cytoarchitectonic organization of the spinal cord in the cat

1952 • 1,595 citations

Reticular formation of the brain

1959 • 1,213 citations

Biological and biochemical bases of behavior

1958 • 1,180 citations

Response of cutaneous sensory units with unmyelinated fibers to noxious stimuli.

1969 • 1,011 citations

CONDUCTION VELOCITY AND DIAMETER OF NERVE FIBERS

1939 • 897 citations

Physiological properties of unmyelinated fiber projection to the spinal cord

1966 • 836 citations

Reshaping the Village Test for investigating service brand attachment

2014 • 771 citations

Analgesia from Electrical Stimulation in the Brainstem of the Rat

1971 • 751 citations

Pain reduction by focal electrical stimulation of the brain: An anatomical and behavioral analysis

1974 • 707 citations

HANDBUCH DER NEUROLOGIE

1912 • 691 citations

Spinal neurons specifically excited by noxious or thermal stimuli: marginal zone of the dorsal horn.

1970 • 678 citations

ASCENDING AXON DEGENERATION FOLLOWING ANTEROLATERAL CORDOTOMY. AN EXPERIMENTAL STUDY IN THE MONKEY

1960 • 678 citations

Responses of Single Dorsal Cord Cells to Peripheral Cutaneous Unmyelinated Fibres

1965 • 564 citations

Cutaneous Mechanoreceptors and Nociceptors

1973 • 561 citations

Some ascending pathways in the brain stem reticular formation.

1958 • 546 citations

Sensations Evoked by Stimulation in the Midbrain of Man

1969 • 541 citations

Approach‐avoidance analysis of rat diencephalon

1963 • 511 citations

SOME NEUROLOGICAL SPECIES DIFFERENCES ‐ A POSTERIORI*

1969 • 484 citations

Analgesia from electrical stimulation of the periaqueductal gray matter in the cat: behavioral observations and inhibitory effects on spinal cord interneurons

1973 • 425 citations

Segmental and supraspinal actions on dorsal horn neurons responding to noxious and non-noxious skin stimuli

1975 • 425 citations

PAIN AND THE NEUROSURGEON A Forty-Year Experience

1970 • 355 citations

Responses of primate spinothalamic tract neurons to natural stimulation of hindlimb.

1974 • 344 citations

Pain and the neurosurgeon : a forty-year experience

1969 • 338 citations

TERMINATION OF THE CENTRAL PAIN PATHWAY IN MAN: THE CONSCIOUS APPRECIATION OF PAIN

1957 • 315 citations

Neurophysiology Studied in Man

1973 • 296 citations

Thalamic afferents from the spinal cord and trigeminal nuclei. An experimental anatomical study in the rat.

1967 • 289 citations

Cord cells responding to fine myelinated afferents from viscera, muscle and skin

1968 • 268 citations

CORD CELLS RESPONDING TO TOUCH, DAMAGE, AND TEMPERATURE OF SKIN

1960 • 267 citations

Inhibition of afferent transmission in cuneate nucleus during voluntary movement in the cat

1972 • 254 citations

Stimulation-produced Analgesia: Development of Tolerance and Cross-Tolerance to Morphine

1975 • 250 citations

Learning Motivated by Electrical Stimulation of the Brain

2017 • 250 citations

Nociceptor-driven dorsal horn neurones in the lumbar spinal cord of the cat

1976 • 242 citations

THE SENSORY AND MOTOR ROLE OF IMPULSES TRAVELLING IN THE DORSAL COLUMNS TOWARDS CEREBRAL CORTEX

1970 • 235 citations

PAIN REACTIONS UPON STIMULATION OF THE TECTUM MESENCEPHALI

1954 • 229 citations

Somatic stimuli exciting spinothalamic projections to thalamic neurons in cat and monkey

1961 • 225 citations

AN EXTRALEMNISCAL SENSORY SYSTEM IN THE BRAIN

1953 • 212 citations

Dual organization of the exteroceptive components of the cat's gracile nucleus

1964 • 212 citations

Responses of dorsal horn cells of M. mulatta to cutaneous and sural nerve A and C fiber stimuli.

1969 • 205 citations

Neuroanatomical substrates of nociception in the spinal cord

1975 • 199 citations

The termination of the spinothalamic tract in the cat an experimental study with silver impregnation methods

1971 • 199 citations

Responses of spinocervical tract neurones to natural stimulation of identified cutaneous receptors

1969 • 198 citations

Unit analysis of nociceptive mechanisms in the thalamus of the awake squirrel monkey.

1966 • 195 citations

Location of cells of origin of spinothalamic tract in lumbar enlargement of the monkey.

1973 • 194 citations

A New Spinal Pathway for Cutaneous Impulses

1955 • 193 citations

SENSORY PROPERTIES OF NEURONS IN THE MESENCEPHALIC RETICULAR FORMATION

1964 • 190 citations

Thalamic afferents from the dorsal column nuclei. An experimental anatomical study in the rat

1967 • 183 citations

Degeneration studies of long ascending fiber systems in the cat brain stem

1959 • 179 citations

The ventral spinothalamic tract and other ascending systems of the ventral funiculus of the spinal cord

1975 • 172 citations

Types of neurone in and around the intermediate nucleus of the lumbosacral cord

1960 • 166 citations

Non-primary afferents to the nucleus gracilis from the lumbar cord of the cat

1973 • 164 citations

DUALITY OF UNIT DISCHARGES FROM CAT CENTRUM MEDIANUM IN RESPONSE TO NATURAL AND ELECTRICAL STIMULATION

1962 • 163 citations

The tract of Lissauer in relation to sensory transmission in the dorsal horn of spinal cord in the macaque monkey

1973 • 157 citations

The spinocervical tract: Dorsal column linkage, conduction velocity, primary afferent spectrum

1965 • 156 citations

Confirmation of the location of spinothalamic neurons in the cat and monkey by the retrograde transport of horseradish peroxidase

1975 • 154 citations

CEREBRAL STRUCTURES INVOLVED IN TRANSMISSION AND ELABORATION OF NOXIOUS STIMULATION

1955 • 154 citations

Neurophysiological characterization of the anterolateral spinal cord neurons contributing to pain perception in man

1975 • 154 citations

post‐synaptic excitation and inhibition from primary afferents in neurones of the spinocervical tract

1968 • 147 citations

Somatic stimuli, spinal pathways, and size of cutaneous fibers influencing unit activity in the medial medulary reticular formation

1969 • 140 citations

Functional organization in nucleus gracilis of the cat

1960 • 140 citations

The dorsal column system: II. Functional properties and bulbar relay of the postsynaptic fibres of the cat's fasciculus gracilis

1975 • 139 citations

EFFECTS OF DISCRETE BRAINSTEM LESIONS IN CATS ON PERCEPTION OF NOXIOUS STIMULATION

1958 • 138 citations

Electrical stimulation in the nervous system: The current status of electrical stimulation of the nervous system for relief of pain

1975 • 138 citations

Location of cells of origin of the spinothalamic tract in the lumbar enlargement of cat

1972 • 137 citations

Functional organization of long, second-order afferents in the dorsal funiculus

1968 • 136 citations

Distribution of responses to somatic afferent stimuli in the diencephalon of the cat under chloralose anesthesia

1960 • 135 citations

Quantitative measurement of neural post-stimulation excitability with behavioral methods

1975 • 132 citations

Ascending projections from marginal zone (Lamina I) neurons of the spinal dorsal horn

1975 • 128 citations

The termination of the cervicothalamic tract in the cat. An experimental study with silver impregnation methods

1970 • 127 citations

The termination of secondary somatosensory neurons within the thalamus of Macaca mulatta: An Experimental Degeneration Study

1961 • 127 citations

Effects of descending impulses on transmission through the spinocervical tract

1971 • 126 citations

Local, segmental and supraspinal interaction with a dorsolateral spinal cutaneous afferent system

1964 • 125 citations

Inhibition of primate spinothalamic tract neurons by stimulation in the region of the nucleus raphe magnus

1976 • 124 citations

Pain reactivity of monkeys after lesions to the dorsal and lateral columns of the spinal cord

1971 • 124 citations

Modulation of sensory transmission in cat lemniscal system during voluntary movement

1971 • 123 citations

Location and somatotopic organization of the cells of origin of the spino-cervical tract

1973 • 122 citations

Neurophysiological characterization of the anterolateral quadrant neurons subserving pain in M. Mulatta

1975 • 121 citations

Two Ascending Spinal Pathways in the Ventral Part of the Cord

1962 • 120 citations

Organization and receptive fields of primate spinothalamic tract neurons

1975 • 112 citations

The termination in the thalamus and the zona incerta of fibres from the dorsal column nuclei (DCN) in the cat. An experimental study with silver impregnation methods

1971 • 111 citations

Behavioral measurement of the neural refractory period and its application to intracranial self-stimulation.

1964 • 105 citations

Cells of origin of the spinothalamic tract in the cat and rat

1968 • 105 citations

Ascending Spinal Hindlimb Pathways in the Cat

1964 • 105 citations

Some properties of spinal neurons projecting to the medial brain-stem reticular formation

1975 • 105 citations

Basic Research in Paraplegia.

1963 • 104 citations

Non-primary afferents to the cuneate nucleus in the brachial dorsal funiculus of the cat

1974 • 103 citations

THE PROPERTIES OF GROWING NERVE FIBERS

1939 • 100 citations

Function of Posterior Columns in Man

1965 • 99 citations

Spino‐bulbar, spino‐thalamic and medial lemniscal connections in the american opossum, Didelphis marsupialis virginiana

1972 • 98 citations

Cutaneous afferent fibre collaterals in the dorsal columns of the cat

1968 • 93 citations

The course of ascending fibers in the spinal cord of the cat essential to the recognition of painful stimuli

1954 • 92 citations

Effects of stimulation of sensorimotor cortex on primate spinothalamic neurons

1974 • 92 citations

The dorsal column system: I. Existence of long ascending postsynaptic fibres in the cat's fasciculus gracilis

1975 • 92 citations

Neurons of the Medial Diencephalon. I. Somatosensory Responses and Caudate Inhibition

1967 • 90 citations

Fearlike behavior elicited from dorsomedial thalamus of cat.

1962 • 90 citations

Characteristics of spinal neurones responding to cutaneous myelinated and unmyelinated fibres*

1972 • 90 citations

Differential localization in dorsal funiculus of fibres originating from different receptors

1968 • 88 citations

Convergent Thalamic and Cortical Projections — The Non-Specific System

1973 • 88 citations

The exteroceptive properties of neurones in the somatic part of the posterior group (PO)

1972 • 86 citations

Spinal afferents to the lateral cervical nucleus in the cat. An experimental study

1953 • 84 citations

Somatic sensory properties of caudal bulbar reticular neurons in the cat (Felis domestica)

1968 • 82 citations

The primate spinothalamic tract as demonstrated by anterolateral cordotomy and commissural myelotomy

1976 • 81 citations

The lateral cervical nucleus of cat, dog and man

1970 • 80 citations

THE LATERAL CERVICAL NUCLEUS OF THE CAT; AN ELECTROPHYSIOLOGICAL STUDY

1966 • 80 citations

Tactile Pathways from the Hindlimb to the Cerebral Cortex in Cat

1962 • 80 citations

Ascending and Long Spinal Pathways: Dorsal Columns, Spinocervical Tract and Spinothalamic Tract

1973 • 79 citations

The Location of the Thalamic Relay in the Spino‐Cervico‐Lemniscal Path

1965 • 77 citations

Physiological laminar organization of the dorsal horn of M. mulatta

1974 • 77 citations

Handbuch der Neurologie.

1936 • 77 citations

FUNCTIONAL PROPERTIES OF NEURONS IN THE LATERAL CERVICAL NUCLEUS OF THE CAT

1964 • 76 citations

THE TERMINATION OF SPINOTHALAMIC FIBRES IN THE CAT AS STUDIED BY THE METHOD OF TERMINAL DEGENERATION

1952 • 75 citations

Spinal cord coding of graded nonnoxious and noxious temperature increases

1975 • 75 citations

Some Properties of the Thalamic Relay Cells in the Spino-Cervico-Lemniscal Path

1966 • 74 citations

Conduction of the effects of noxious stimulation by short-fiber multisynaptic systems of the spinal cord in the rat

1973 • 73 citations

Responses of Bulboreticular Units To Somatic Stimuli Eliciting Escape Behavior In The Cat

1971 • 73 citations

Origin of spino-thalamic tract in monkeys

1974 • 73 citations

Evoking conditioned fear by electrical stimulation of subcortical structures in the monkey brain.

1956 • 72 citations

Pain threshold alterations by brain stimulation in the monkey

1971 • 71 citations

Responses Evoked in the Brain Stem by Tooth Stimulation

1955 • 68 citations

A study of single axons in the cat's medial lemniscus

1974 • 65 citations

Cells of origin of the spinocervical tract in the monkey

1974 • 65 citations

Some properties of spinal connections of the cat's dorsal column nuclei which do not involve the dorsal columns

1973 • 64 citations

DORSAL CORDOTOMY FOR PAINFUL PHANTOM LIMB

1948 • 64 citations

Dorsal column nuclei afferents in the lateral funiculus of the cat: Distribution pattern and absence of sprouting after chronic deafferentation

1975 • 63 citations

The course of the fibers arising from the nucleus gracilis and cuneatus of the cat

1951 • 63 citations

Central connections of a cervical nucleus (nucleus cervicalis lateralis of the cat)

1955 • 62 citations

Paresthesias and EEG potentials evoked by stimulation of the dorsal funiculi in man

1972 • 59 citations

Responses of primate spinothalamic tract neurons to electrical stimulation of hindlimb peripheral nerves

1975 • 59 citations

The diencephalic course and termination of the medial lemniscus and the brachium conjunctivum

1932 • 58 citations

The ascending projections of the dorsolateral funiculus of the spinal cord in the primate

1975 • 58 citations

Somatosensory Pathways

1972 • 57 citations

An Inquiry into the Neurophysiological Basis for Pain

1969 • 57 citations

Responses of the rat dorsal column system to mechanical stimulation of the hind paw

1963 • 57 citations

An Anatomical Analysis of the White Matter in the Brain Stem of the Cat

1962 • 55 citations

Single neurons in the rat medulla responsive to nociceptive stimulation

1970 • 53 citations

Reduction of the response of cat spinothalamic neurons to graded mechanical stimuli by electrical stimulation of the lower brain stem

1975 • 53 citations

The lateral cervical nucleus of the Japanese monkey (Macaca fuscata)

1967 • 52 citations

Sensory hind-limb representation in the Sml cortex of the cat after spinal tractotomies

1968 • 51 citations

Afferent projections to the lateral cervical nucleus: a microelectrode study

1963 • 51 citations

Central Pain. Observations in Man with Chronic Implanted Electrodes in the Midbrain Tegmentum

1966 • 51 citations

Lamina-specific suppression of dorsal horn unit activity by nitrous oxide and by hyperventilation.

1971 • 51 citations

The intensity function and reinforcing properties of brain stimulation that elicits attack

1969 • 47 citations

The Anatomophysiological Basis of Somatosensory Discrimination

1965 • 47 citations

MICROELECTRODE STUDIES ON SENSORY AFFERENTS IN THE POSTERIOR FUNICULUS OF CAT

1956 • 46 citations

Commissural Myelotomy

1969 • 44 citations

The lateral cervical nucleus of the raccoon

1965 • 39 citations

Unit analysis of nonspecific thalamic responses to high-intensity cutaneous input in the cat

1974 • 38 citations

Lateral cervical nucleus of the dog: anatomical and microelectrode studies

1965 • 38 citations

Postsynaptic fibres in the dorsal columns and their relay in the nucleus gracilis

1972 • 37 citations

The spinal input to the posterior group in the cat. An electrophysiological investigation

1972 • 36 citations

The course and termination of the medial lemniscus in man

1948 • 36 citations

The gigantocellular reticular region and its spinal afferents: a light and electron microscope study in the cat.

1970 • 34 citations

Activation of neurons in the gracile nucleus by two afferent pathways in the rat

1972 • 34 citations

Strong and Elwyn's Human Neuroanatomy.

1964 • 33 citations

Ventrolateral spinal cord afferents to the brain stem in the domestic pig

1968 • 33 citations

Cervicothalamic tract in the rhesus monkey

1971 • 33 citations

Strong and Elwyn's Human Neuroanatomy.

1960 • 32 citations

The effects of stimulating the somatic sensory cortex on single neurones in the posterior group (PO) of the cat

1972 • 31 citations

POSTERIOR CORDOTOMY FOR RELIEF OF PHANTOM LIMB PAIN

1946 • 31 citations

Interactions of cutaneous myelinated (A) and non-myelinated (C) fibres on transmission through the spinocervical tract

1973 • 25 citations

Transmission of sensory information through the lemniscal pathway during sleep.

1967 • 25 citations

Postchordotomy Studies of Pain Threshold

1957 • 25 citations

Descending control of the spinocervical tract in decerebrate cats

1970 • 24 citations

Specific nociceptive fibers projecting from spinal cord neurons to the brain: a possible pathway for pain

1973 • 24 citations

A quantitative investigation of somatosensory coding in single cells of the cat mesencephalic reticular formation

1976 • 23 citations

Spinal cord coding of graded non-noxious and noxious temperature increases

1976 • 23 citations

Recent advances on the neurophysiological bases of pain sensation.

1975 • 22 citations

Neurons in the rostral mesencephalic reticular formation of the cat responding specifically to noxious mechanical stimulation

1976 • 22 citations

Anterolateral Cordotomy – its Effectiveness in Relieving Pain of Non-Malignant Disease

1963 • 22 citations

Effects from the somatic sensory cortex on transmission through the spinocervical tract

1974 • 21 citations

CONNECTIONS OF THE TEMPORAL LOBE IN MAN

1959 • 20 citations

Electrophysiological investigation of lemniscal and paralemniscal input to the midbrain reticular formation

1963 • 20 citations

Response of somatosensory cerebral neurons to stimulation of dorsal and dorsolateral spinal funiculi

1974 • 20 citations

Patterns of response in spinocervical tract neurones to different stimuli of long duration

1970 • 20 citations

Inference of refractory period, temporal summation, and adaptation from behavior in chronic implants: Midbrain pain systems.

1973 • 18 citations

Cervicothalamic tract in the dog

1970 • 18 citations

A study of fiber systems within the spinal cord of the domestic pig that subserve pain

1968 • 17 citations

A single neuron analysis of mesencephalic reticular formation responses to high intensity cutaneous input in cat

1974 • 16 citations

Adaptation of aversive brain stimulation III. Excitability characteristics of behaviorally relevant neural substrates

1976 • 15 citations

On the possible functional role of afferent pathways in skin sensation

1975 • 15 citations

Concerning the conduction of touch and deep sensibilities through the spinal cord.

1948 • 15 citations

Descending influences on spinocervical tract cell discharges evoked by non-myelinated cutaneous afferent nerve fibres

1973 • 14 citations

Characteristics of two ascending pathways which originate in spinal dorsal horn of M. mulatta

1971 • 13 citations

C-Fiber Responses in the Ventrolateral Column of the Cat Spinal Cord

1969 • 12 citations

Somatic afferents to the cat subthalamus.

1968 • 11 citations

Adaptation of aversive brain stimulation II. Effects of current level and pulse frequency

1976 • 10 citations

Response properties of units in the dorsal column nuclei of the freely moving rat: changes as a function of behaviour

1971 • 9 citations

Localization of centripetal pathways of the human brain by recording of evoked potentials.

1951 • 7 citations

Adaptation of aversive brain stimulation: Effects of pulse frequency

1975 • 7 citations

The actions and locations in the spinal cord of descending pathways that inhibit transmission through the spinocervical tract.

1972 • 7 citations

Surgical treatment of painful phantom limb; a preliminary report.

1946 • 6 citations

Behavioral indices for neural systems involved in pain and fear responses of monkeys

1970 • 6 citations

Input characteristics and rostral projection of dorsal horn neurones in the monkey.

1975 • 6 citations

Proceedings: Inhibition of transmission through the spinocervical tract from localized areas of the sensorimotor cortex.

1976 • 6 citations

Correlation of overt escape behavior, multiunit thalamic activity, and midbrain lemniscal stimulation in rats.

1975 • 5 citations

SWITCH‐OFF BEHAVIOR AND ELECTRICAL STIMULATION OF THE PONS IN CATS

1967 • 5 citations

[The pain threshold after spinothalamic chordotomy].

1970 • 5 citations

On the occurrence of lymphatic vessels in the adrenal gland of the white rat.

1971 • 3 citations

Deleted Work

1955 • 0 citations