Metabolites and analogs of 1α,25-dihydroxyvitamin D3: evaluation of actions in bone

Stimulation of bone resorption and inhibition of bone formation in vitro by human tumour necrosis factors

1986 • 1,433 citations

1,25-Dihydroxyvitamin D3 increases synthesis of the vitamin K-dependent bone protein by osteosarcoma cells.

1980 • 503 citations

Calcium Transport in Perfused Duodena from Normal Chicks: Enhancement within Fourteen Minutes of Exposure to 1,25-Dihydroxyvitamin D₃*

1984 • 262 citations

Effects of vitamin D3 metabolites on cytosolic free calcium in confluent mouse osteoblasts.

1987 • 246 citations

Transcriptional regulation of osteopontin production in rat osteosarcoma cells by type beta transforming growth factor.

1988 • 206 citations

1,25-Dihydroxyvitamin D3 Regulates the Biosynthesis of Osteopontin, a Bone-Derived Cell Attachment Protein, in Clonal Osteoblast-Like Osteosarcoma Cells

1987 • 187 citations

Prostaglandins and bone: physiology and pathophysiology

1999 • 182 citations

Vitamin D-regulated gene expression.

1993 • 181 citations

Regulation of type I collagen synthesis by 1,25-dihydroxyvitamin D3 in human osteosarcoma cells.

1988 • 154 citations

Stimulation of Bone Resorption in Vitro by Synthetic Transforming Growth Factor-Alpha

1985 • 154 citations

Regulation of collagen synthesis in fetal rat calvaria by 1,25-dihydroxyvitamin D3.

1982 • 149 citations

Nongenomic Actions of 1,25-Dihydroxyvitamin D₃in Rat Osteosarcoma Cells: Structure-Function Studies Using Ligand Analogs*

1991 • 126 citations

Generation of inositol phosphates, diacylglycerol and calcium fluxes in myoblasts treated with 1,25-dihydroxyvitamin D3

1993 • 118 citations

Transcriptional Regulation of Osteocalcin Production by Transforming Growth Factor-β in Rat Osteoblast-Like Cells

1989 • 114 citations

Cyclic AMP-mediated stabilization of osteocalcin mRNA in rat osteoblast-like cells treated with parathyroid hormone.

1988 • 102 citations

Bone remodeling signaled by a dihydropyridine- and phenylalkylamine-sensitive calcium channel.

1989 • 102 citations

Early Effects of Parathyroid Hormone and Thyrocalcitonin on Bone in Organ Culture

1967 • 80 citations

1,25-Dihydroxyvitamin D3 analog structure-function assessment of the rapid stimulation of intestinal calcium absorption (transcaltachia)

1992 • 74 citations

Vitamin D3 analogs stimulate calcium currents in rat osteosarcoma cells.

1994 • 63 citations

Highly potent transcriptional activation by 16-ene derivatives of 1,25-dihydroxyvitamin D3. Lack of modulation by 9-cis-retinoic acid of response to 1,25-dihydroxyvitamin D3 or its derivatives.

1994 • 61 citations

Multiple calcium channel transcripts in rat osteosarcoma cells: selective activation of alpha 1D isoform by parathyroid hormone.

1995 • 54 citations

Production of 1α,25-Dihydroxy-3-epi-vitamin D3 in two rat osteosarcoma cell lines (UMR 106 and ROS 17/2.8): existence of the C-3 epimerization pathway in ROS 17/2.8 cells in which the C-24 oxidation pathway is not expressed

1999 • 53 citations

24,25-Dihydroxyvitamin D3 Suppresses the Rapid Actions of 1,25-Dihydroxyvitamin D3 and Parathyroid Hormone on Calcium Transport in Chick Intestine

1999 • 51 citations

1β, 25(OH)2-vitamin D3 is an antagonist of 1α,25(OH)2-vitamin D3 stimulated transcaltachia (The rapid hormonal stimulation of intestinal calcium transport)

1992 • 46 citations

Prostaglandins and bone

1995 • 43 citations

1α,25-dihydroxyvitamin D3-induced increments in hepatocyte cytosolic calcium and lysophosphatidylinositol: Inhibition by pertussis toxin and 1ß,25-dihydroxyvitamin D3

1990 • 43 citations

Ribozyme Ablation Demonstrates That the Cardiac Subtype of the Voltage-sensitive Calcium Channel Is the Molecular Transducer of 1,25-Dihydroxyvitamin D3-stimulated Calcium Influx in Osteoblastic Cells

2000 • 39 citations

Transcriptional control of vitamin D‐regulated proteins

1992 • 37 citations

Asymmetric total synthesis, x-ray crystallography, and preliminary biological evaluation of 1-(1'-hydroxyethyl)-25-hydroxyvitamin D3 analogs of natural calcitriol

1993 • 31 citations

Contribution of cyclooxygenase-1 and cyclooxygenase-2 to prostanoid formation by human enterocytes stimulated by calcium ionophore and inflammatory agents

1998 • 26 citations

Growth inhibitory effects on human colon adenocarcinoma-derived Caco-2 cells and calcemic potential of 1 alpha,25-dihydroxyvitamin D3 analogs: structure-function relationships.

1995 • 21 citations

Effect of 1,25(OH)2D3 and its analogues on membrane phosphoinositide turnover and [Ca2+]i in Caco-2 cells

1993 • 16 citations

Total synthesis of 25-Hydroxy-16,23E-diene Vitamin D3 and 1α,25-Dihydroxy-16,23E-diene Vitamin D3: separation of genomic and nongenomic vitamin D Activities

1998 • 12 citations

1,25‐dihydroxyvitamin D₃ stimulates the phosphorylation of two acidic membrane proteins of 42,000 and 48,000 daltons in rat colonocytes: An effect modulated by vitamin D status

1995 • 5 citations

ChemInform Abstract: Asymmetric Total Synthesis, X‐Ray Crystallography, and Preliminary Biological Evaluation of 1‐(1′‐Hydroxyethyl)‐25‐hydroxyvitamin D3 Analogues of Natural Calcitriol.

1994 • 3 citations