Mapping of the C3b-binding site of CR1 and construction of a (CR1)2-F(ab')2 chimeric complement inhibitor.

DNA sequencing with chain-terminating inhibitors

1977 • 69,181 citations

Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphenylglycoluril

1978 • 4,673 citations

Soluble Human Complement Receptor Type 1: In Vivo Inhibitor of Complement Suppressing Post-Ischemic Myocardial Inflammation and Necrosis

1990 • 989 citations

Comparison of the effector functions of human immunoglobulins using a matched set of chimeric antibodies.

1987 • 615 citations

Membrane Cofactor Protein (MCP or CD46): Newest Member of the Regulators of Complement Activation Gene Cluster

1991 • 582 citations

Primate erythrocyte-immune complex-clearing mechanism.

1983 • 495 citations

Large scale isolation of functionally active components of the human complement system.

1981 • 446 citations

Regulation of the amplification C3 convertase of human complement by an inhibitory protein isolated from human erythrocyte membrane

1979 • 444 citations

Immunoglobulin gene expression in transformed lymphoid cells.

1983 • 400 citations

Unique role of the complement receptor CR1 in the degradation of C3b associated with immune complexes.

1982 • 335 citations

Structure-function relationships of the complement components

1989 • 311 citations

Intersection of the complement and immune systems: a signal transduction complex of the B lymphocyte-containing complement receptor type 2 and CD19.

1991 • 301 citations

Generation of three different fragments of bound C3 with purified factor I or serum. I. Requirements for factor H vs CR1 cofactor activity.

1982 • 296 citations

Activation of the alternative complement pathway due to resistance of zymosan-bound.

1977 • 283 citations

Recombinant antibodies possessing novel effector functions

1984 • 282 citations

Identification of distinct C3b and C4b recognition sites in the human C3b/C4b receptor (CR1, CD35) by deletion mutagenesis.

1988 • 274 citations

Complement receptor is an inhibitor of the complement cascade.

1981 • 267 citations

Human C3b/C4b receptor (CR1). Demonstration of long homologous repeating domains that are composed of the short consensus repeats characteristics of C3/C4 binding proteins.

1987 • 267 citations

Identification of a 145,000 Mr membrane protein as the C3d receptor (CR2) of human B lymphocytes.

1984 • 257 citations

Suppression of the Immune Response by a Soluble Complement Receptor of B Lymphocytes

1991 • 242 citations

Mapping of the Epstein-Barr virus and C3dg binding sites to a common domain on complement receptor type 2.

1989 • 154 citations

Structural requirements for C3d,g/Epstein-Barr virus receptor (CR2/CD21) ligand binding, internalization, and viral infection.

1990 • 146 citations

Sites within the complement C3b/C4b receptor important for the specificity of ligand binding.

1991 • 127 citations

A study of the structure of human complement component factor H by Fourier transform infrared spectroscopy and secondary structure averaging methods

1988 • 105 citations

Molecular interactions of complement receptors on B lymphocytes: a CR1/CR2 complex distinct from the CR2/CD19 complex.

1991 • 101 citations

PMA induces the ligand-independent internalization of CR1 on human neutrophils.

1985 • 95 citations

Interaction of iC3b with recombinant isotypic and chimeric forms of CR2.

1991 • 82 citations

Identification of an alternative polyadenylation site in the human C3b/C4b receptor (complement receptor type 1) transcriptional unit and prediction of a secreted form of complement receptor type 1.

1988 • 80 citations

Structure-function relationships for the IL-2 receptor system. V. Structure-activity analysis of modified and truncated forms of the Tac receptor protein: site-specific mutagenesis of cysteine residues.

1988 • 37 citations

Reduced activity of DAF on complement enzymes bound to alternative pathway activators. Similarity with Factor H.

1990 • 5 citations