The Fission Yeast Ran Gtpase Is Required for Microtubule Integrity

The p21 Cdk-interacting protein Cip1 is a potent inhibitor of G1 cyclin-dependent kinases

1993 • 5,680 citations

[56] Molecular genetic analysis of fission yeast Schizosaccharomyces pombe

1991 • 3,691 citations

Heterologous modules for efficient and versatile PCR-based gene targeting inSchizosaccharomyces pombe

1998 • 2,230 citations

Beyond self-assembly: From microtubules to morphogenesis

1986 • 1,334 citations

NUCLEOCYTOPLASMIC TRANSPORT: The Soluble Phase

1998 • 1,184 citations

Genetic instability and darwinian selection in tumours

1999 • 748 citations

Definition of individual components within the cytoskeleton of Trypanosoma brucei by a library of monoclonal antibodies

1989 • 650 citations

The use of cell division cycle mutants to investigate the control of microtubule distribution in the fission yeast Schizosaccharomyces pombe

1988 • 493 citations

Generation of GTP-bound Ran by RCC1 is required for chromatin-induced mitotic spindle formation

1999 • 492 citations

Using GFP in FRET-based applications

1999 • 482 citations

The NDA3 gene of fission yeast encodes β-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis

1984 • 473 citations

The product of the spindle formation gene sad1+ associates with the fission yeast spindle pole body and is essential for viability.

1995 • 406 citations

Stimulation of Microtubule Aster Formation and Spindle Assembly by the Small GTPase Ran

1999 • 393 citations

tea1 and the Microtubular Cytoskeleton Are Important for Generating Global Spatial Order within the Fission Yeast Cell

1997 • 354 citations

The Ran GTPase regulates mitotic spindle assembly

1999 • 349 citations

Structural View of the Ran–Importin β Interaction at 2.3 Å Resolution

1999 • 344 citations

Structure of the nuclear transport complex karyopherin-β2–Ran˙GppNHp

1999 • 340 citations

Analysis of the Saccharomyces Spindle Pole by Matrix-assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry

1998 • 318 citations

Self-Organization of Microtubule Asters Induced in Xenopus Egg Extracts by GTP-Bound Ran

1999 • 305 citations

Regulation of the fission yeast transcription factor Pap1 by oxidative stress: requirement for the nuclear export factor Crm1 (Exportin) and the stress-activated MAP kinase Sty1/Spc1

1998 • 304 citations

A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.

1996 • 298 citations

Kinesin-related cut 7 protein associates with mitotic and meiotic spindles in fission yeast

1992 • 262 citations

Yeast Bim1p Promotes the G1-specific Dynamics of Microtubules

1999 • 248 citations

Versatile shuttle vectors and genomic libraries for use with Schizosaccharomyces pombe

1992 • 241 citations

The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex

1997 • 239 citations

Premature initiation of mitosis in yeast lacking RCC1 or an interacting GTPase

1991 • 231 citations

CDK2 encodes a 33-kDa cyclin A-associated protein kinase and is expressed before CDC2 in the cell cycle.

1992 • 230 citations

Identification of the pleiotropic cell division cycle gene NDA2 as one of two different α-tubulin genes in schizosaccharomyces pombe

1984 • 216 citations

Mal3, the Fission Yeast Homologue of the Human APC-interacting Protein EB-1 Is Required for Microtubule Integrity and the Maintenance of Cell Form

1997 • 215 citations

Spindle assembly and the art of regulating microtubule dynamics by MAPs and Stathmin/Op18

2000 • 211 citations

Fission yeast minichromosome loss mutants mis cause lethal aneuploidy and replication abnormality.

1994 • 211 citations

Fission yeast cell morphogenesis: identification of new genes and analysis of their role during the cell cycle.

1995 • 210 citations

Transport of macromolecules between the nucleus and the cytoplasm.

1998 • 207 citations

When Overexpressed, a Novel Centrosomal Protein, RanBPM, Causes Ectopic Microtubule Nucleation Similar to γ-Tubulin

1998 • 188 citations

BIM1Encodes a Microtubule-binding Protein in Yeast

1997 • 179 citations

Commentary: the fission yeast microtubule cytoskeleton

1998 • 174 citations

Microtubule dynamics and tubulin interacting proteins

2000 • 171 citations

cut11⁺: A Gene Required for Cell Cycle-dependent Spindle Pole Body Anchoring in the Nuclear Envelope and Bipolar Spindle Formation inSchizosaccharomyces pombe

1998 • 166 citations

The Ran decathlon: multiple roles of Ran

2000 • 162 citations

A cytokinesis checkpoint requiring the yeast homologue of an APC-binding protein

1998 • 158 citations

Complex formation between Mad1p, Bub1p and Bub3p is crucial for spindle checkpoint function

2000 • 155 citations

The spindle checkpoint: two transitions, two pathways

2000 • 152 citations

Large‐scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP‐fusion genomic DNA library

2000 • 149 citations

Regulation of Cell Polarity by Microtubules in Fission Yeast

1998 • 146 citations

Ran-GTP stabilises microtubule asters and inhibits nuclear assembly in Xenopus egg extracts

1999 • 145 citations

A Novel Nuclear Export Signal Sensitive to Oxidative Stress in the Fission Yeast Transcription Factor Pap1

1999 • 141 citations

Sequential alterations in the nuclear chromatin region during mitosis of the fission yeast Schizosa Ccharomyces Pombe-: Video fluorescence microscopy of synchronously growing wild-type and cold-sensitive cdc mutants by using a dna-binding fluorescent probe

1981 • 135 citations

A fission yeast RCC1-related protein is required for the mitosis to interphase transition.

1994 • 134 citations

The fission yeast SPB component Cut12 links bipolar spindle formation to mitotic control

1998 • 131 citations

mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe

1998 • 113 citations

The search for the primary function of the Ran GTPase continues

1996 • 111 citations

A functional homologue of the RNA1 gene product in Schizosaccharomyces pombe: purification, biochemical characterization, and identification of a leucine-rich repeat motif.

1993 • 93 citations

imp2, a New Component of the Actin Ring in the Fission Yeast Schizosaccharomyces pombe

1998 • 64 citations

Cell Cycle Specificity of Certain Antimicrotubular Drugs in Schizosaccharomyces pombe

1982 • 40 citations

Perturbations in the spi1p GTPase Cycle of Schizosaccharomyces pombe through Its GTPase-Activating Protein and Guanine Nucleotide Exchange Factor Components Result in Similar Phenotypic Consequences

1996 • 38 citations

Chromosome segregation: Dual control ensures fidelity

1999 • 37 citations

Fission Yeast mal2⁺ Is Required for Chromosome Segregation

1996 • 31 citations

The Identification of cDNAs That Affect the Mitosis-to-Interphase Transition in Schizosaccharomyces pombe, Including sbp1, Which Encodes a spi1p-GTP–Binding Protein

1998 • 18 citations