Single and repeated administration of neuroleptic drugs to rats: Effects on striatal dopamine-sensitive adenylate cyclase and locomotor activity produced by tranylcypromine and L-tryptophan or L-dopa

A stereotaxic atlas of the rat brain

1967 • 4,710 citations

Amphetamine and apomorphine responses in the rat following 6-OHDA lesions of the nucleus accumbens septi and corpus striatum

1975 • 1,741 citations

A simple and sensitive saturation assay method for the measurement of adenosine 3′:5′-cyclic monophosphate

1971 • 1,547 citations

Dopamine-sensitive adenylate cyclase in caudate nucleus of rat brain, and its similarity to the “dopamine receptor”

1972 • 1,022 citations

Striatal Dopamine Release after Amphetamine or Nerve Degeneration Revealed by Rotational Behaviour

1971 • 912 citations

STUDIES IN VIVO ON THE RELATIONSHIP BETWEEN BRAIN TRYPTOPHAN, BRAIN 5‐HT SYNTHESIS AND HYPERACTIVITY IN RATS TREATED WITH A MONOAMINE OXIDASE INHIBITOR AND L‐TRYPTOPHAN

1971 • 667 citations

Dopamine Receptors in the Brain

1975 • 528 citations

Antischizophrenic Drugs and Brain Cholinergic Receptors

1974 • 474 citations

Dopamine-Sensitive Adenylate Cyclase in Mammalian Brain: A Possible Site of Action of Antipsychotic Drugs

1974 • 450 citations

Anti-muscarinic properties of neuroleptics and drug-induced Parkinsonism

1974 • 382 citations

DOPAMINE IN THE MESOLIMBIC SYSTEM OF THE RAT BRAIN: ENDOGENOUS LEVELS AND THE EFFECTS OF DRUGS ON THE UPTAKE MECHANISM AND STIMULATION OF ADENYLATE CYCLASE ACTIVITY

1974 • 342 citations

The Action of Neuroleptic Drugs on Dopamine-Stimulated Adenosine Cyclic 3',5'-Monophosphate Production in Rat Neostriatum and Limbic Forebrain

1974 • 240 citations

Enhancement of Dopamine-Stimulated Adenylate Cyclase Activity in Rat Caudate after Lesions in Substantia Nigra: Evidence for Denervation Supersensitivity

1974 • 228 citations

Behavioral evidence for dopaminergic supersensitivity after chronic haloperidol

1974 • 195 citations

The relative importance of dopaminergic and noradrenergic neuronal systems for the stimulation of locomotor activity induced by amphetamine and other drugs

1973 • 184 citations

Effects of drugs on the processes regulating the functional activity of brain 5-hydroxytryptamine

1976 • 182 citations

Inhibitory effect of chlorpromazine on the syndrome of hyperactivity produced by <scp>l</scp>‐tryptophan or 5‐methoxy‐N,N‐dimethyltryptamine in rats treated with a monoamine oxidase inhibitor

1971 • 179 citations

Increased sensitivity to dopaminergic agents after chronic neuroleptic treatment.

1975 • 161 citations

The pharmacology of 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo(b,e)(1,4)diazepine (clozapine).

1971 • 136 citations

The role of brain dopamine in the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats

1974 • 129 citations

Kritische Stellungnahme zum Begriff der Neuroleptika

1971 • 122 citations

Serotonin-sensitive adenylate cyclase activity in immature rat brain

1975 • 115 citations

Dopamine-sensitive adenylate cyclase of the caudate nucleus of rats treated with morphine or haloperidol

1975 • 110 citations

Effect of apomorphine and pimozide on synthesis and turnover of labelled catecholamines in mouse brain

1970 • 93 citations

Dopaminergic supersensitivity in the striatum.

1975 • 91 citations

Dopaminergic denervation supersensitivity and dopamine stimulated adenyl cyclase activity

1973 • 84 citations

Neuronal Basis for the Central Action Of Chlorpromazine

1966 • 80 citations

Differential sensitivity of two dopaminergic structures in rat brain to haloperidol and to clozapine.

1975 • 80 citations

Unilateral 6-hydroxydopamine lesions of nigrostriatal or mesolimbic dopamine-containing terminals and the drug-induced rotation of rats

1975 • 71 citations

Increased platelet aggregation responses to 5‐hydroxytryptamine in patients taking chlorpromazine.

1975 • 67 citations

Neuroleptic antagonism of dyskinetic phenomena

1975 • 66 citations

Drug-induced dopaminergic supersensitivity.

1975 • 64 citations

THE INTERACTION OF NEUROLEPTIC AND MUSCARINIC AGENTS WITH CENTRAL DOPAMINERGIC SYSTEMS

1975 • 62 citations

EVIDENCE CONCERNING THE INVOLVEMENT OF 5‐HYDROXYTRYPTAMINE IN THE LOCOMOTOR ACTIVITY PRODUCED BY AMPHETAMINE OR TRANYLCYPROMINE PLUS <scp>l</scp>‐DOPA

1976 • 54 citations

A comparative pharmacological study of a series of monohydroxylated and methoxylated chlorpromazine derivatives

1965 • 51 citations

Thin-layer chromatography of chlorpromazine metabolites

1973 • 47 citations

Effect of two dopamine receptor blockers on a serotonin-mediated behavioral syndrome in rats

1974 • 46 citations

Tricyclic antidepressive drugs and dopamine-sensitive adenylate cyclase from rat brain striamtum

1975 • 46 citations

[Effect profile of a chemically new broad spectrum neuroleptic of the dibenzo-diazepine group].

1966 • 40 citations

Model metabolites of chlorpromazine and promazine: relative activities in some pharmacological and behavioral tests.

1962 • 37 citations

Dopamine Antagonism and Antischizophrenic Potency of Neuroleptic Drugs

1973 • 35 citations

Behavioral supersensitivity to 5-hydroxytryptophan induced by chronic methysergide pretreatment

1975 • 34 citations

Das Neuroleptikum 100-129/HF-1854 (Clozapin) in der Psychiatrie

1970 • 31 citations

Chemistry of dopamine receptors.

1975 • 29 citations

Limiting factors in the antagonism of neuroleptics on dopamine-sensitive adenylate cyclase

1976 • 28 citations

Elevation of brain GABA concentrations with amino-oxyacetic acid; effect on the hyperactivity syndrome produced by increased 5-hydroxytryptamine synthesis in rats

1976 • 26 citations

Clozapine, a novel major tranquilizer. Clinical experiences and pharmacotherapeutic hypotheses.

1972 • 25 citations

INHIBITION OF 5‐HYDROXYTRYPTAMINE‐INDUCED HUMAN BLOOD PLATELET AGGREGATION BY CHLORPROMAZINE AND ITS METABOLITES

1975 • 18 citations

Antimuscarinic actions of neuroleptic drugs.

1975 • 14 citations

Double-blind Study in Psychopathic Behavior Disorders (Clozapine and Pericyazine)^*

1973 • 9 citations

Zur Frage der therapeutischen Wirksamkeit eines Neuroleptikums bei chronisch Schizophrenen mit Dosierungen oberhalb und unterhalb der "neuroleptischen Schwelle"

1969 • 7 citations

Inhibition of 4, ?-dimethyl-m-tyramine (H 77/77)-induced hypermotil ity in rats by single and repeated administration of chlorpromazine, haloperidol, clozapine and thioridazine

1975 • 5 citations