A stochastic model for the origin and treatment of tumors containing drug-resistant cells

Partial Differential Equations

1982 • 1,798 citations

A STOCHASTIC MODEL OF STEM CELL PROLIFERATION, BASED ON THE GROWTH OF SPLEEN COLONY-FORMING CELLS

1964 • 889 citations

Multitype branching processes;: Theory and applications

1971 • 238 citations

A Stem Cell Model of Human Tumor Growth: Implications for Tumor Cell Clonogenic Assays<xref ref-type="fn" rid="FN2">2</xref>

1983 • 190 citations

A model for the resistance of tumor cells to cancer chemotherapeutic agents

1983 • 159 citations

Resistance to methotrexate due to gene amplification in a patient with acute leukemia.

1984 • 145 citations

Cytologic evidence for gene amplification in methotrexate-resistant cells obtained from a patient with ovarian adenocarcinoma.

1984 • 123 citations

Origin of the Resistance of Leukæmic Cells to Folic Acid Antagonists

1952 • 117 citations

Drug and Hormone Resistance in Neoplasia

2019 • 63 citations

A mathematical model of the effects of drug resistance in cancer chemotherapy

1984 • 32 citations

The effect of cellular differentiation on the development of permanent drug resistance

1985 • 30 citations

Preoperative (Neoadjuvant) Chemotherapy

1986 • 10 citations

Factors Affecting the Development of Permanent Drug Resistance and Its Impact upon Neoadjuvant Chemotherapy

1986 • 6 citations