Endothelin-1 and -3 induce the release of tissue-type plasminogen activator and Von Willebrand factor from endothelial cells

Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor.

1988 • 1,417 citations

Molecular biology and biochemistry of the endothelins

1989 • 620 citations

A Simple, Sensitive Spectrophotometric Assay for Extrinsic (Tissue-Type) Plasminogen Activator Applicable to Measurements in Plasma

1982 • 486 citations

Ion channels and regulation of intracellular calcium in vascular endothelial cells

1989 • 418 citations

Endothelin, a novel endothelium-derived peptide

1989 • 365 citations

Glomerular actions of endothelin in vivo.

1989 • 351 citations

Evidence for the Occurrence of a Fast-Acting Inhibitor for Tissue-Type Plasminogen Activator in Human Plasma

1984 • 345 citations

Immunoreactive endothelin in human plasma: Marked elevations in patients in cardiogenic shock

1989 • 330 citations

Molecular mechanism of action of the vasoconstrictor peptide endothelin

1988 • 317 citations

Bradykinin-induced increases in cytosolic calcium and ionic currents in cultured bovine aortic endothelial cells.

1987 • 292 citations

Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat

1989 • 260 citations

ENDOTHELIN: AN IMPORTANT FACTOR IN ACUTE RENAL FAILURE?

1988 • 214 citations

Autoradiographical Localization of Binding Sites for Porcine [125I]Endothelin-1 in Humans, Pigs, and Rats

1989 • 179 citations

Tissue plasminogen activator release in vivo in response to vasoactive agents

1985 • 179 citations

Calcium entry through receptor-operated channels in bovine pulmonary artery endothelial cells

1987 • 175 citations

Innovative Approaches to Plasminogen Activator Therapy

1989 • 168 citations

Similarities in mode and sites of action of sarafotoxins and endothelins

1989 • 152 citations

Cellular responses to Ca2+ from extracellular and intracellular sources are different as shown by simultaneous measurements of cytosolic Ca2+ and secretion from bovine chromaffin cells.

1989 • 136 citations

Regulation of plasminogen activator secretion in mouse peritoneal macrophages

1979 • 103 citations

A sensitive ELISA for von Willebrand factor (vWf:Ag)

1987 • 101 citations

Thrombin-induced release of von Willebrand factor from endothelial cells is mediated by phospholipid methylation. Prostacyclin synthesis is independent of phospholipid methylation.

1984 • 87 citations

Endothelin: A potent vasoconstrictor associated with coronary vasospasm

1989 • 83 citations

PAF-acether-induced release of tissue-type plasminogen activator from vessel walls

1985 • 65 citations

Perfused rat hindlegs. A model to study plasminogen activator release

1983 • 63 citations

Studies with Endothelin-3 and Endothelin-1 on Rat Blood Pressure and Isolated Tissues

1989 • 52 citations

The Simultaneous Acute Release of Tissue-Type Plasminogen Activator and von Willebrand Factor in the Perfused Rat Hindleg Region

1990 • 46 citations

Vascular Endothelium and Ca2† Antagonists

1988 • 44 citations

Protein Synthesis Inhibition by Cycloheximide Does Not Affect the Acute Release of Tissue-Type Plasminogen Activator

1989 • 23 citations

Interaction of synthetic sarafotoxin with rat vascular endothelin receptors

1989 • 22 citations

Release of tissue‐type plasminogen activator is induced in rats by leukotrienes C₄ and D₄, but not by prostaglandins E₁, E₂ and I₂

1988 • 12 citations

Fibrinolytic activity of endothelin-3

1989 • 10 citations

Mechanisms Involved in Short-Term Changes in Blood Levels of t-PA

2018 • 6 citations

Deleted Work

1955 • 0 citations

Cited By (0)

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