Quantitative studies of the structure of proteins in solution by fourier-transform infrared spectroscopy

Smoothing and Differentiation of Data by Simplified Least Squares Procedures.

1964 • 18,746 citations

Dictionary of protein secondary structure: Pattern recognition of hydrogen‐bonded and geometrical features

1983 • 14,802 citations

An algorithm for the machine calculation of complex Fourier series

1965 • 11,350 citations

`` Direct Search'' Solution of Numerical and Statistical Problems

1961 • 4,193 citations

The hydrogen bond

1960 • 3,255 citations

Infrared and Raman Spectra of Polyatomic Molecules.

1946 • 3,247 citations

Model for the structure of bacteriorhodopsin based on high-resolution electron cryo-microscopy

1990 • 2,969 citations

Fourier Transform Infrared Spectrometry

2006 • 2,868 citations

Examination of the secondary structure of proteins by deconvolved FTIR spectra

1986 • 2,865 citations

Vibrational Spectroscopy and Conformation of Peptides, Polypeptides, and Proteins

1986 • 2,761 citations

Partial least-squares methods for spectral analyses. 1. Relation to other quantitative calibration methods and the extraction of qualitative information

1988 • 2,459 citations

Internal Reflection Spectroscopy

1968 • 1,758 citations

Internal Reflection Spectroscopy

1967 • 1,471 citations

Structure and stability of biological macromolecules

1969 • 1,313 citations

Structure of Myoglobin: A Three-Dimensional Fourier Synthesis at 2 Å. Resolution

1960 • 1,313 citations

Infra-Red and Raman Spectra of Polyatomic Molecules

1946 • 1,288 citations

Fourier Self-Deconvolution: A Method for Resolving Intrinsically Overlapped Bands

1981 • 1,280 citations

Protein secondary structures in water from second-derivative amide I infrared spectra

1990 • 1,271 citations

The Infrared Spectra of Polypeptides in Various Conformations: Amide I and II Bands¹

1961 • 1,089 citations

Helix geometry in proteins

1988 • 1,042 citations

Physical Techniques in Biological Research

1963 • 941 citations

Fourier transform infrared spectrometry

1986 • 795 citations

[13] Resolution-enhanced fourier transform infrared spectroscopy of enzymes

1986 • 690 citations

Analysis of protein circular dichroism spectra for secondary structure using a simple matrix multiplication

1986 • 549 citations

Secondary structure and dosage of soluble and membrane proteins by attenuated total reflection Fourier‐transform infrared spectroscopy on hydrated films

1990 • 526 citations

Automatic identification of secondary structure in globular proteins

1977 • 507 citations

Protein structure by Fourier transform infrared spectroscopy: Second derivative spectra

1983 • 502 citations

Protein Structure Determination in Solution by Nuclear Magnetic Resonance Spectroscopy

1989 • 444 citations

Perturbation Treatment of the Characteristic Vibrations of Polypeptide Chains in Various Configurations

1960 • 433 citations

Determination of the secondary structure content of proteins in aqueous solutions from their amide I and amide II infrared bands. Comparison between classical and partial least-squares methods

1990 • 412 citations

Spectroscopy of biological systems

1987 • 411 citations

Infrared Spectra and Protein Conformations in Aqueous Solutions

1967 • 408 citations

The Scope and Limitations of Curve Fitting

1980 • 381 citations

α-Helical coiled coils — a widespread motif in proteins

1986 • 350 citations

Fourier transforms in the computation of self-deconvoluted and first-order derivative spectra of overlapped band contours

1981 • 334 citations

Structural and conformational changes of β-lactoglobulin B: an infrared spectroscopic study of the effect of pH and temperature

1988 • 332 citations

X-Ray Photographs of Crystalline Pepsin

1934 • 311 citations

Studies of peptides forming 310- and .alpha.-helixes and .beta.-bend ribbon structures in organic solution and in model biomembranes by Fourier transform infrared spectroscopy

1991 • 293 citations

The pH-dependent bilayer destabilization by an amphipathic peptide

1987 • 292 citations

Structure of Synthetic Polypeptides

1950 • 275 citations

Why do globular proteins fit the limited set of foldin patterns?

1987 • 272 citations

Determination of protein secondary structure using factor analysis of infrared spectra

1990 • 260 citations

Fourier Transform Infrared Techniques for Probing Membrane Protein Structure

1988 • 248 citations

Noise in Fourier self-deconvolution

1981 • 248 citations

On the Spectral Subtraction of Water from the FT-IR Spectra of Aqueous Solutions of Proteins

1989 • 222 citations

Precision in Condensed Phase Vibrational Spectroscopy

1982 • 212 citations

Resolution of Overlapping Absorption Bands by Least Squares Procedures.

1966 • 205 citations

Application of laser Raman and infrared spectroscopy to the analysis of membrane structure

1979 • 186 citations

Conformational transitions in poly(l-lysine): studies using Fourier transform infrared spectroscopy

1989 • 167 citations

The solution structure of concanavalin A probed by FT-IR spectroscopy

1988 • 157 citations

Vibrational analysis of peptides, polypeptides, and proteins. V. Normal vibrations of β‐turns

1980 • 157 citations

Protein secondary structure from fourier transform infrared spectroscopy: A data base analysis

1991 • 156 citations

Intensities and other spectral parameters of infrared amide bands of polypeptides in the β‐ and random forms

1973 • 155 citations

Fourier transform infrared spectroscopic studies of calcium-binding proteins

1991 • 146 citations

Quantitative IR spectrophotometry of peptide compounds in water (H₂O) solutions. III. Estimation of the protein secondary structure

1990 • 144 citations

Infrared Spectrum of the Purple Membrane: Clue to a Proton Conduction Mechanism?

1982 • 144 citations

A Generalized Approach to Derivative Spectroscopy

1987 • 140 citations

Materials Characterization Using Factor Analysis of FT-IR Spectra. Part 1: Results

1985 • 138 citations

Secondary Structure of Diphtheria Toxin and Its Fragments Interacting with acidic Liposomes Studied by Polarized Infrared Spectroscopy

1989 • 134 citations

Structure of cytochrome b5 in solution by Fourier-transform infrared spectroscopy

1989 • 131 citations

Fourier transform infrared study of proteins with parallel β-chains

1987 • 128 citations

Fourier transform methods for spectral resolution enhancement

1988 • 114 citations

A Study of the Structure of Fibronectin

1981 • 110 citations

Analytical Applications of FT-IR to Molecular and Biological Systems

1980 • 106 citations

Fourier transform infrared spectroscopic investigation of the interaction between myelin basic protein and dimyristoylphosphatidylglycerol bilayers

1987 • 101 citations

An Algorithm for the Reproducible Spectral Subtraction of Water from the FT-IR Spectra of Proteins in Dilute Solutions and Adsorbed Monolayers

1986 • 101 citations

Comparison of various molecular forms of bovine trypsin: correlation of infrared spectra with x-ray crystal structures

1991 • 96 citations

Protein secondary structure of the isolated photosystem II reaction center and conformational changes studied by Fourier transform infrared spectroscopy

1991 • 96 citations

Calmodulin and troponin C structures studied by Fourier transform infrared spectroscopy: effects of calcium and magnesium binding

1989 • 93 citations

Spectroscopy in the Biomedical Sciences

2018 • 89 citations

Infrared spectroscopic discrimination between α‐ and 3₁₀‐helices in globular proteins

1991 • 86 citations

Deconvolution, Derivation, and Smoothing of Spectra Using Fourier Transforms

1984 • 85 citations

Materials Characterization Using Factor Analysis of FT-IR Spectra. Part 2: Mathematical and Statistical Considerations

1985 • 84 citations

Combined deconvolution and curve fitting for quantitative analysis of unresolved spectral bands

1990 • 84 citations

Anomalous Amide I Infrared Absorption of Purple Membrane

1979 • 83 citations

XXVIII. Visibility of interference-fringes in the focus of a telescope

1891 • 83 citations

Infrared spectroscopic study of photoreceptor membrane and purple membrane. Protein secondary structure and hydrogen deuterium exchange.

1986 • 83 citations

Vibrational circular dichroism of polypeptides, V. A study of 3₁₀‐helical‐octapeptides

1986 • 80 citations

Infrared spectroscopic discrimination between alpha- and 3(10)-helices in globular proteins. Reexamination of Amide I infrared bands of alpha-lactalbumin and their assignment to secondary structures.

1991 • 80 citations

Normal vibrations of proteins: Glucagon

1982 • 80 citations

Membrane Spectroscopy.

1982 • 74 citations

Infrared spectroscopic characterization of the structural changes connected with the E1→E2 transition in the Ca2+-ATPase of sarcoplasmic reticulum.

1987 • 73 citations

Conformational properties of azurin in solution as determined from resolution‐enhanced Fourier‐transform infrared spectra

1987 • 73 citations

Computer analyses of characteristic infrared bands of globular proteins

1975 • 72 citations

Effect of metal ion binding on the secondary structure of bovine .alpha.-lactalbumin as examined by infrared spectroscopy

1991 • 70 citations

Fusogenic activity of SIV (Simian Immunodeficiency Virus) peptides located in the GP32 NH2 terminal domain

1991 • 70 citations

Secondary structure and orientation of the amphipathic peptide GALA in lipid structures

1991 • 69 citations

A New Line-Narrowing Procedure Based on Fourier Self-Deconvolution, Maximum Entropy, and Linear Prediction

1991 • 69 citations

Fourier transform infrared investigation of the Escherichia coli methionine aporepressor

1987 • 66 citations

Spectroscopy of biological molecules

1986 • 63 citations

Smoothing of spectral data in the Fourier domain

1982 • 63 citations

Solution structure of the 45-residue magnesium ATP-binding peptide of adenylate kinase as examined by 2-D NMR, FTIR, and CD spectroscopy

1988 • 59 citations

Optical Techniques in Biological Research

1984 • 56 citations

An infrared spectroscopic study of β‐galactosidase structure in aqueous solutions

1989 • 55 citations

Protein conformational transitions in the erythrocyte membrane

1971 • 51 citations

Comparison of .alpha.-lactalbumin and lysozyme using vibrational circular dichroism. Evidence for a difference in crystal and solution structures

1991 • 49 citations

Infrared Micro-Imaging of Atherosclerotic Arteries

1991 • 47 citations

The secondary structure of two recombinant human growth factors, platelet-derived growth factor and basic fibroblast growth factor, as determined by Fourier-transform infrared spectroscopy

1991 • 46 citations

Fourier transform infrared spectroscopic studies on the secondary structure of the Ca2+-ATPase of sarcoplasmic reticulum

1989 • 45 citations

Lipid-induced changes in the secondary structure of snake venom cardiotoxins.

1988 • 42 citations

FTIR studies of secondary structures of bovine insulin and its derivatives

1991 • 41 citations

Vibrational analysis of peptides, polypeptides, and proteins. XXIV. Conformation of poly(α‐aminoisobutyric acid)

1984 • 38 citations

Secondary structure and orientation of a chemically synthesized mitochondrial signal sequence in phospholipid bilayers

1989 • 38 citations

Calculation and use of protein‐derived conformation‐related spectra for the estimate of the secondary structure of proteins from their infrared spectra

1977 • 37 citations

The structure of proteins in aqueous solutions: An assessment of triose phosphate isomerase structure by fourier-transform infrared spectroscopy

1988 • 35 citations

Ueber die chemischen und optischen Eigenschaften des Blutfarbstoffs

1864 • 33 citations

Infrared spectroscopic studies of detergent‐solubilized uncoupling protein from brown‐adipose‐tissue mitochondria

1990 • 31 citations

The road from poly(α-amino acids) to the prediction of protein conformation

1987 • 28 citations

Characteristics of the LOMEP Line-Narrowing Method

1991 • 23 citations

Emerging Techniques in Biophysical FT-IR

1988 • 22 citations

A Fourier transform infrared spectroscopic (FTIR) study of porcine and bovine pancreatic phospholipase A2 and their interaction with substrate analogues and a transition-state inhibitor

1990 • 21 citations

Protein conformational transitions in sarcoplasmic reticulum membranes

1985 • 19 citations

The Variable-Temperature FT-IR Study of the Secondary Structure of γ-Globulin, Chymotrypsin, Serum Albumin, and β-Lactoglobulin in Aqueous Solution

1989 • 18 citations

Secondary structure changes of diphtheria toxin interacting with asolectin liposomes: an infrared spectroscopy study

1989 • 17 citations

What spectroscopy can still tell us about the secondary structure of bacteriorhodopsin

1991 • 11 citations

Lipid-protein interactions. The mitochondrial complex III-phosphatidylcholine-water system

1988 • 10 citations

Secondary Structure of the lac Repressor Headpiece

1982 • 9 citations

Infrared study of the secondary structure of lac repressor and its tryptic core

1980 • 9 citations

A computer program for normal-coordinate calculations of a polypeptide chain with any conformation and length

1986 • 6 citations