Mithramycin Selectively Inhibits the Transcriptional Activity of a Transfected Human C-myc Gene

Cell-specific regulation of the c-myc gene by lymphocyte mitogens and platelet-derived growth factor

1983 • 2,350 citations

Nerve growth factor and epidermal growth factor induce rapid transient changes in proto-oncogene transcription in PC12 cells.

1985 • 888 citations

A block to elongation is largely responsible for decreased transcription of c-myc in differentiated HL60 cells

1986 • 834 citations

Cell-cycle control of c-myc but not c-ras expression is lost following chemical transformation

1984 • 785 citations

THE myc ONCOGENE: ITS ROLE IN TRANSFORMATION AND DIFFERENTIATION

1986 • 714 citations

Constitutive c-myc oncogene expression blocks mouse erythroleukaemia cell differentiation but not commitment

1986 • 536 citations

Microinjected c- myc as a Competence Factor

1985 • 361 citations

Deregulated expression of c-myc by murine erythroleukaemia cells prevents differentiation

1986 • 321 citations

Expression of a transfected human c-myconcogene inhibits differentiation of a mouse erythroleukaemia cell line

1986 • 309 citations

Participation of c- myc Protein in DNA Synthesis of Human Cells

1986 • 282 citations

Chromomycin, mithramycin, and olivomycin binding sites on heterogeneous DNA. Footprinting with methidiumpropyl-EDTA.cntdot.iron(II)

1983 • 218 citations

Mithramycin blocks protein binding and function of the SV40 early promoter.

1989 • 137 citations

Tumor Necrosis Factor Reduces c- myc Expression and Cooperates with Interferon-γ in HeLa Cells

1986 • 109 citations

Mithramycin inhibition of ribonucleic acid synthesis.

1966 • 94 citations

Preliminary Observations on the Therapy of the Myeloid Blast Phase of Chronic Granulocytic Leukemia with Plicamycin and Hydroxyurea

1986 • 94 citations

Effect of polyamine depletion on c-myc expression in human colon carcinoma cells.

1988 • 92 citations

Rapid Communication: Mithramycin Selectively Inhibits Transcription Of G-C Containing DNA

1987 • 79 citations

Regulation of expression of the c‐Myc proto‐oncogene

1987 • 78 citations

The v- and c-myc oncogene proteins colocalize in situ with small nuclear ribonucleoprotein particles.

1987 • 77 citations

Contributions of transcriptional and post-transcriptional mechanisms to the regulation of c-myc expression in mouse erythroleukemia cells.

1987 • 74 citations

Expression of the c-myb and c-myc genes is regulated independently in differentiating mouse erythroleukemia cells by common processes of premature transcription arrest and increased mRNA turnover.

1988 • 68 citations

Terminal Erythroid Differentiation in the K-562 Cell Line by 1-β-d-Arabinofuranosylcytosine: Accompaniment by c-myc Messenger RNA Decrease

1986 • 60 citations

Transcriptional Inactivation of c-myc and the Transferrin Receptor in Dibutyryl Cyclic AMP-Treated HL-60 Cells

1987 • 54 citations

Dibutyryl cyclic adenosine monophosphate reduces expression of c-myc during HL-60 differentiation

1986 • 43 citations

Truncation does not abrogate transcriptional downregulation of the c-myc gene by sodium butyrate in Burkitt's lymphoma cells.

1987 • 32 citations

Post-transcriptional mechanisms of deregulation of MYC following conversion of a human B cell line by Epstein-Barr virus.

1989 • 32 citations

Transcriptional inactivation of c-myc and the transferrin receptor in dibutyryl cyclic AMP-treated HL-60 cells.

1987 • 31 citations

DMSO induced modulation of c-myc steady-state RNA levels in a variety of different cell lines.

1989 • 30 citations

In vivo differentiation of blast-phase chronic granulocytic leukemia. Expression of c-myc and c-abl protooncogenes.

1985 • 26 citations

Recombinant human tumor necrosis factor alpha regulates c-myc expression in HL-60 cells at the level of transcription

1987 • 23 citations

Mouse fibroblasts transformed with the human c-myc gene express a high level of mRNA but a low level of c-myc protein and are non-tumorigenic in nude mice.

1989 • 19 citations

Selective inhibition of c-myc expression by the ribonucleic acid synthesis inhibitor mithramycin

1988 • 17 citations

Effects of teleocidin on the morphology and c-myc expression of hepatoma cells which are not inhibited by protein kinase antagonists

1987 • 13 citations

Mode of action of antitumour antibiotic: Part II--Evidence for intercalation of mithramycin between DNA bases in the presence of Mg2+.

1979 • 8 citations