The Polymerase Chain Reaction: DNA Extraction and Amplification

PCR protocols — A guide to methods and applications

1990 • 12,897 citations

Sequence and organization of the human mitochondrial genome

1981 • 9,348 citations

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

1985 • 9,128 citations

Dynamics of mitochondrial DNA evolution in animals: amplification and sequencing with conserved primers.

1989 • 4,904 citations

Specific Enzymatic Amplification of DNA In Vitro: The Polymerase Chain Reaction

1986 • 3,400 citations

Generation of single-stranded DNA by the polymerase chain reaction and its application to direct sequencing of the HLA-DQA locus.

1988 • 1,582 citations

Effects of primer-template mismatches on the polymerase chain reaction: Human immunodeficiency virus type 1 model studies

1990 • 1,037 citations

OPTIMIZATION OF PCRs

1990 • 632 citations

The Molecule of the Year

1989 • 489 citations

SAMPLE PREPARATION FROM BLOOD, CELLS, AND OTHER FLUIDS

1990 • 427 citations

Mitochondrial DNA in the bark weevils: size, structure and heteroplasmy.

1989 • 242 citations

A comparison of the small ribosomal RNA genes from the mitochondrial DNA of the great apes and humans: sequence, structure, evolution, and phylogenetic implications.

1986 • 210 citations

AMPLIFYING ANCIENT DNA

1990 • 200 citations

Duplication and remoulding of tRNA genes during the evolutionary rearrangement of mitochondrial genomes

1987 • 186 citations

PROCEDURES TO MINIMIZE PCR-PRODUCT CARRY-OVER

1990 • 172 citations

DEGENERATE PRIMERS FOR DNA AMPLIFICATION

1990 • 80 citations

Atypical mitochondrial DNA from the deep-sea scallop Placopecten magellanicus

1987 • 79 citations

Evolution of mitochondrial ribosomal RNA in insects as shown by the polymerase chain reaction

1990 • 47 citations

A+A+A+C

1964 • 8 citations