Caspase-mediated cleavage is not required for the activity of presenilins in amyloidogenesis and NOTCH signaling

Programmed Cell Death in Animal Development

1997 • 2,690 citations

Assembly and aggregation properties of synthetic Alzheimer's A4/beta amyloid peptide analogs.

1992 • 982 citations

Amyloid β-Protein and the Genetics of Alzheimer's Disease

1996 • 794 citations

Membrane Topology of the C. elegans SEL-12 Presenilin

1996 • 204 citations

Presenilins: Genes for Life and Death

1997 • 149 citations

Generation of Anti-apoptotic Presenilin-2 Polypeptides by Alternative Transcription, Proteolysis, and Caspase-3 Cleavage

1997 • 109 citations

Caspases: A treatment target for neurodegenerative disease?

1997 • 52 citations