Adhesive and invasive features in gliomas

Tenascin: an extracellular matrix protein involved in tissue interactions during fetal development and oncogenesis

1986 • 989 citations

Glioma Invasion in the Central Nervous System

1996 • 574 citations

Dichotomy of astrocytoma migration and proliferation

1996 • 389 citations

Human glioma-mesenchymal extracellular matrix antigen defined by monoclonal antibody.

1983 • 370 citations

Differential expression of membrane-type matrix metalloproteinase and its correlation with gelatinase A activation in human malignant brain tumors in vivo and in vitro.

1996 • 278 citations

Galectin-3 Is a Novel Substrate for Human Matrix Metalloproteinases-2 and -9

1994 • 259 citations

Matrix metalloproteinases and tissue inhibitors of metalloproteinases in human gliomas

1995 • 233 citations

Production of matrix metalloproteinases and tissue inhibitor of metalloproteinases-1 by human brain tumors

1994 • 223 citations

Characterization of integrin receptors in normal and neoplastic human brain.

1993 • 221 citations

CD44 mediates human glioma cell adhesion and invasion in vitro.

1994 • 217 citations

Determinants of human astrocytoma migration.

1994 • 204 citations

Functional evidence that cell surface galectin-3 mediates homotypic cell adhesion.

1995 • 197 citations

Expression and localization of 72 kDa type IV collagenase (MMP-2) in human malignant gliomas in vivo

1996 • 195 citations

Expression of Matrix Metalloproteinases and Their Tissue Inhibitors in Human Brain Tumors

1998 • 185 citations

Comparison of cell adhesion molecule expression between glioblastoma multiforme and autologous normal brain tissue

1995 • 184 citations

Expression of metalloproteinases and metalloproteinase inhibitors by fetal astrocytes and glioma cells.

1990 • 180 citations

Expression and localization of 92 kDa type IV collagenase/gelatinase B (MMP-9) in human gliomas

1996 • 165 citations

Expression of the endogenous galactose-binding protein galectin-3 correlates with the malignant potential of tumors in the central nervous system

1997 • 163 citations

Tenascin expression in astrocytomas correlates with angiogenesis.

1995 • 159 citations

Matrix metalloproteinases and their biological function in human gliomas

1999 • 151 citations

Migration of brain tumor cells on extracellular matrix proteins in vitro correlates with tumor type and grade and involves alphaV and beta1 integrins.

1996 • 143 citations

Tenascin-C expression by angiogenic vessels in human astrocytomas and by human brain endothelial cells in vitro.

1996 • 136 citations

Cell-Extracellular Matrix Interaction in Glioma Invasion

1999 • 126 citations

Expression of tenascin in human gliomas: its relation to histological malignancy, tumor dedifferentiation and angiogenesis

1993 • 122 citations

Differential expression of the CD44 molecule in human brain tumours

1992 • 122 citations

Localization of the CD44 Glycoprotein to Fibrous Astrocytes in Normal White Matter and to Reactive Astrocytes in Active Lesions in Multiple Sclerosis

1991 • 122 citations

Mechanisms of Glioma Invasion: Role of Matrix-Metalloproteinases

1997 • 120 citations

Identification of a Glioblastoma-Associated Tenascin-C Isoform by a High Affinity Recombinant Antibody

1999 • 116 citations

Immunohistochemical localisation of macromolecules of the basement membrane and extracellular matrix of human gliomas and meningiomas

1985 • 97 citations

Collagens, integrins and the mesenchymal drift in glioblastomas: A comparison of biopsy specimens, spheroid and early monolayer cultures

1994 • 96 citations

Tenascin: a modulator of cell growth

1992 • 96 citations

Neural antigens in oligodendrogliomas and dysembryoplastic neuroepithelial tumors

1997 • 91 citations

Suppression of CD44 expression decreases migration and invasion of human glioma cells

1996 • 85 citations

GFAP, FVIII/RAg, Laminin, and fibronectin in gliosarcomas: An immunohistochemical study

1984 • 78 citations

Hyaluronate binding and CD44 expression in human glioblastoma cells and astrocytes

1992 • 76 citations

GLIOMA INVASIONIN VITRO IS MEDIATED BY CD44-HYALURONAN INTERACTIONS

1997 • 76 citations

Supratentorial Low-Grade Gliomas

1990 • 76 citations

Distribution of Extracellular Matrix Proteins in Primary Human Brain Tumours: An Immunohistochemical Analysis

1987 • 73 citations

Immunohistochemical localization of extracellular matrix proteins in human glioma, both in vivo and in vitro

1996 • 71 citations

Differential expression of tenascin-C and tenascin-X in human astrocytomas

1997 • 71 citations

Secretion of matrix metalloproteinase-2 (72 kD gelatinase/type IV collagenase = gelatinase A) by malignant human glioma cell lines: implications for the growth and cellular invasion of the extracellular matrix

1996 • 71 citations

Extracellular matrix proteins inhibit proliferation, upregulate migration and induce morphological changes in human glioma cell lines

1995 • 68 citations

Galectin‐3, a β‐Galactoside‐Binding Animal Lectin, Binds to Neural Recognition Molecules

1995 • 68 citations

Contrasting migratory response of astrocytoma cells to tenascin mediated by different integrins

1996 • 67 citations

Expression of the neural cell adhesion molecule in astrocytic tumors

1998 • 66 citations

CD44 plays a role in adhesive interactions between glioma cells and extracellular matrix components

1994 • 64 citations

Galectin‐3 and galectin‐3‐binding site expression in human adult astrocytic tumours and related angiogenesis

1999 • 63 citations

Transmembrane neural cell-adhesion molecule (NCAM), but not glycosyl-phosphatidylinositol-anchored NCAM, down-regulates secretion of matrix metalloproteinases.

1993 • 62 citations

Heterogeneous regional expression patterns of matrix metalloproteinases in human malignant gliomas

1999 • 60 citations

Expression of variant CD44 epitopes in human astrocytic brain tumors

1995 • 59 citations

Role of CD44 in the invasiveness of glioblastoma multiforme and the noninvasiveness of meningioma: An immunohistochemistry study

1995 • 59 citations

Glioma cell adhesion and migration on human brain sections.

1998 • 56 citations

The distribution of laminin in human brain tumors: An immunohistochemical study

1985 • 55 citations

Expression of Matrix Metalloproteinases and Their Inhibitors in Human Brain Tumors

1999 • 54 citations

Cytotactin binding: inhibition of stimulated proliferation and intracellular alkalinization in fibroblasts.

1991 • 54 citations

Expression of adhesion molecules and extracellular matrix proteins in glioblastomas: relation to angiogenesis and spread

1996 • 54 citations

Expression of cathepsin D during the progression of human gliomas

1996 • 50 citations

Role of extracellular matrix proteins in regulation of human glioma cell invasion in vitro

1996 • 47 citations

Expression of CD44 splice variants in human primary brain tumors

1995 • 43 citations

Laminin expression by glial fibrillary acidic protein positive cells in human gliomas

1999 • 40 citations

CD44 expression in astrocytic tumors.

1997 • 38 citations

Immunolocalization of monoclonal antibody-defined extracellular matrix antigens in human brain tumors

1985 • 38 citations

Migratory, invasive and metastatic capacity of NCAM transfected rat glioma cells

1993 • 33 citations

Correlation of expression of NCAM and GD3 ganglioside to motile behaviour in neoplastic glia.

1998 • 33 citations

Characterization of a membrane-bound metalloendoprotease of rat C6 glioblastoma cells.

1994 • 32 citations

Differential binding of anti-CD44 on human gliomas in vitro

1993 • 31 citations

Role of high molecular weight extracellular matrix proteins in glioma cell migration

1997 • 28 citations

An inverse correlation between expression of NCAM-A and the matrix-metalloproteinases gelatinase-A and gelatinase-B in human glioma cells in vitro

1997 • 27 citations

Immunolocalization of cathepsin D in the human central nervous system and central nervous system neoplasms

1990 • 22 citations

CD44 expression in primary and recurrent oligodendrogliomas and in adjacent gliotic brain tissue

1999 • 21 citations

CD44 is involved in migration but not spreading of astrocytoma cells in vitro.

1997 • 19 citations

Paucity of retinoic acid receptor alpha (RAR alpha) nuclear immunostaining in gliomas and inability of retinoic acid to influence neural cell adhesion molecule (NCAM) expression.

1999 • 18 citations

Localization of CD44 at the Invasive Margin of Glioblastomas by Immunoelectron Microscopy

1997 • 18 citations

Differential expressions of CD44 variants in tumors affecting the central nervous system

1999 • 17 citations

Degradation of collagen type IV by C6 astrocytoma cells

1995 • 13 citations

Expression of the cluster 1 antigen (neural cell adhesion molecule) in neuroectodermal tumours.

1991 • 13 citations

Expression of cathepsin D in human astrocytic neoplasias.

1995 • 10 citations

Deleted Work

1955 • 0 citations