Do human renal cell carcinomas arise by a double-loss mechanism?

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

1986 • 2,968 citations

Expression of recessive alleles by chromosomal mechanisms in retinoblastoma

1983 • 1,952 citations

Human Retinoblastoma Susceptibility Gene: Cloning, Identification, and Sequence

1987 • 1,436 citations

Cancer: Principles and Practice of Oncology.

1986 • 1,140 citations

Chromosomal Imbalance in the Aniridia-Wilms' Tumor Association: 11p Interstitial Deletion

1978 • 726 citations

Hereditary Renal-Cell Carcinoma Associated with a Chromosomal Translocation

1979 • 649 citations

Mutation and Cancer: A Model for Wilms' Tumor of the Kidney<xref ref-type="fn" rid="FN2">2</xref>

1972 • 623 citations

Chromosome 5 allele loss in human colorectal carcinomas

1987 • 566 citations

Loss of alleles at loci on human chromosome 11 during genesis of Wilms' tumour

1984 • 538 citations

Loss of genes on chromosome 22 in tumorigenesis of human acoustic neuroma

1986 • 524 citations

Loss of heterozygosity of chromosome 3p markers in small-cell lung cancer

1987 • 472 citations

Retinoblastoma and Subband Deletion of Chromosome 13

1978 • 455 citations

Somatic deletion and duplication of genes on chromosome 11 in Wilms' tumours

1984 • 426 citations

Development of homozygosity for chromosome 11p markers in Wilms' tumour

1984 • 411 citations

Loss of genes on the short arm of chromosome 11 in bladder cancer

1985 • 360 citations

Consistent chromosome 3p deletion and loss of heterozygosity in renal cell carcinoma.

1988 • 343 citations

Mutation and cancer: neuroblastoma and pheochromocytoma.

1972 • 341 citations

Loss of a Harvey ras allele in sporadic Wilms' tumour

1984 • 336 citations

Familial Renal Cell Carcinoma with a 3;11 Chromosome Translocation Limited to Tumor Cells

1982 • 260 citations

Loss of heterozygosity in human ductal breast tumors indicates a recessive mutation on chromosome 13.

1987 • 206 citations

Specific chromosome aberration in human renal cell carcinoma

1987 • 195 citations

Cytogenetic studies of tumor tissue from patients with nonfamilial renal cell carcinoma.

1986 • 176 citations

George Stewart Smith.

1975 • 156 citations

Chromosomes in kidney, ureter, and bladder cancer

1986 • 124 citations

Abnormalities at chromosome region 3p12–14 characterize clear cell renal carcinoma

1987 • 99 citations

Proximal 3p deletion in renal cell carcinoma cells from a patient with von Hippel-Lindau disease

1987 • 62 citations

The two-mutational-event theory in medullary thyroid cancer.

1979 • 46 citations

Renal Carcinoma (Hypernephroma) Occurring in 5 Siblings

1972 • 46 citations

AN IMMUNOLOGICAL APPROACH TO THE THERAPY OF CANCER?

1971 • 42 citations

Familial renal carcinoma

1982 • 40 citations

HYPERNEPHROMA-FAMILIAL OCCURRENCE IN ONE FAMILY

1960 • 37 citations

A SURVEY OF THE FAMILIAL INCIDENCE OF ADENOCARCINOMA OF THE KIDNEY

1967 • 19 citations

Silent Adenocarcinoma of the Kidney with Solitary Metastases Occurring in Brothers

1953 • 17 citations

Renal carcinoma in mother and daughter

1972 • 16 citations

Familial Renal Tumours

1969 • 16 citations

Renal Cell Carcinoma Diagnosed in Three Generations of a Single Family

1979 • 15 citations

Natural and radiation carcinogenesis in man III. Radiation carcinogenesis

1965 • 12 citations

RENAL‐CELL CARCINOMA IN SIBLINGS: A CASE REPORT

1968 • 10 citations

Renal-cell carcinoma Unusual occurrence in four members of one family

1973 • 10 citations

Bilateral renal cell carcinoma—unusual occurrence in three members of one family

1981 • 8 citations

Hypernephroma in two brothers.

1977 • 7 citations

Some Indications for the Diagnosis and Treatment of Aortic Aneurism

1878 • 6 citations

Renal Carcinoma with a Strong Family History

1986 • 4 citations