Ethanol inhibits development of dendrites and synapses in rat hippocampal pyramidal neuron cultures

The Synaptic Organization of the Brain

2004 • 3,543 citations

The establishment of polarity by hippocampal neurons in culture

1988 • 1,820 citations

Fetal Alcohol Syndrome in Adolescents and Adults

1991 • 912 citations

Fetal alcohol syndrome: diagnosis, epidemiology, prevention, and treatment

1997 • 895 citations

Alcohol‐Induced Neuronal Loss in Developing Rats: Increased Brain Damage with Binge Exposure

1990 • 558 citations

Moderate Prenatal Alcohol Exposure: Effects on Child IQ and Learning Problems at Age 7 1/2 Years

1990 • 549 citations

The distribution of synapsin I and synaptophysin in hippocampal neurons developing in culture

1991 • 463 citations

Experimental observations on the development of polarity by hippocampal neurons in culture.

1989 • 419 citations

Bone morphogenetic proteins in the nervous system

1997 • 409 citations

Prenatal ethanol exposure permanently reduces the number of pyramidal neurons in rat hippocampus

1981 • 384 citations

Rat Hippocampal Neurons in Low-Density Culture

1998 • 343 citations

The distribution of glutamate receptors in cultured rat hippocampal neurons: Postsynaptic clustering of AMPA selective subunits

1993 • 340 citations

Glial heterogeneity may define the three-dimensional shape of mouse mesencephalic dopaminergic neurones

1984 • 326 citations

Prenatal Exposure to Ethanol Alters the Organization of Hippocampal Mossy Fibers in Rats

1981 • 283 citations

Osteogenic protein-1 induces dendritic growth in rat sympathetic neurons

1995 • 238 citations

An electron microscopic study of the development of axons and dendrites by hippocampal neurons in culture. II. Synaptic relationships

1984 • 229 citations

Ethanol and guanine nucleotide binding proteins: a selective interaction

1990 • 217 citations

Synaptogenesis in hippocampal cultures: evidence indicating that axons and dendrites become competent to form synapses at different stages of neuronal development

1994 • 206 citations

Characterization of GABAergic neurons in hippocampal cell cultures

1994 • 201 citations

MAP2 expression and neuritic outgrowth and branching are coregulated through region-specific neuro-astroglial interactions

1987 • 201 citations

Alcohol inhibits cell-cell adhesion mediated by human L1 [published erratum appears in J Cell Biol 1996 Jun;133(5):1139-40]

1996 • 184 citations

Effects of Ethanol Exposure during the Third Trimester Equivalent on Neuron Number in Rat Hippocampus and Dentate Gyrus

1986 • 173 citations

Differential neuronal loss following early postnatal alcohol exposure

1989 • 157 citations

A Golgi study of mouse hippocampal CA1 pyramidal neurons following perinatal ethanol exposure

1981 • 137 citations

Ethanol Inhibits L1-mediated Neurite Outgrowth in Postnatal Rat Cerebellar Granule Cells

1999 • 123 citations

Morphologic evidence for a delay of neuronal maturation in fetal alcohol exposure

1981 • 122 citations

Alcohol action on a neuronal membrane receptor: evidence for a direct interaction with the receptor protein.

1994 • 115 citations

Ethanol Neurotoxicity: Effects on Neurite Formation and Neurotrophic Factor Production in Vitro

1985 • 103 citations

Intracellular recording and injection study of corticospinal neurons in the rat somatosensory cortex: Effect of prenatal exposure to ethanol

1990 • 103 citations

An Inhibitory Fragment Derived from Protein Kinase Cε Prevents Enhancement of Nerve Growth Factor Responses by Ethanol and Phorbol Esters

1997 • 102 citations

Cutoff in potency implicates alcohol inhibition of N-methyl-D-aspartate receptors in alcohol intoxication.

1995 • 100 citations

Effects of alcohol exposure during different periods of development: changes in hippocampal mossy fibers

1985 • 98 citations

Regional differences in glial-derived factors that promote dendritic outgrowth from mouse cortical neurons in vitro

1994 • 95 citations

Divergent effects of astroglial and microglial secretions on neuron growth and survival

1992 • 95 citations

Ethanol enhances growth factor activation of mitogen-activated protein kinases by a protein kinase C-dependent mechanism.

1995 • 85 citations

Responsiveness of cultured septal and hippocampal neurons to ethanol and neurotrophic substances

1994 • 85 citations

Ethanol enhances growth factor-induced neurite formation in PC12 cells

1991 • 84 citations

In vitro regulation of neuronal morphogenesis and polarity by astrocyte-derived factors

1990 • 82 citations

Modulation of ethanol neurotoxicity by nerve growth factor

1993 • 75 citations

Prenatal exposure to ethanol induces changes in the nerve growth factor and its receptor in proliferating astrocytes in primary culture

1994 • 73 citations

Effects of ethanol on cultured glial cells: proliferation and glutamine synthetase activity

1984 • 69 citations

Cerebellar histogenesis and synaptic maturation following pre- and postnatal alcohol administration

1984 • 68 citations

Ethanol Reduces Expression of the Nerve Growth Factor Receptor, But Not Nerve Growth Factor Protein Levels in the Neonatal Rat Cerebellum

1997 • 67 citations

Ethanol enhances neurite outgrowth in primary cultures of rat cerebellar macroneurons

1993 • 63 citations

Alterations in neuronal development in the substantia nigra pars compacta following in utero ethanol exposure: Immunohistochemical and Golgi studies

1993 • 63 citations

Effect of prenatal exposure to ethanol on the ultrastructure of layer V of mature rat somatosensory cortex

1989 • 59 citations

NMDA Prevents Alcohol‐Induced Neuronal Cell Death of Cerebellar Granule Cells in Culture

1995 • 58 citations

Regulation of glutamate uptake in astrocytes continuously exposed to ethanol

1997 • 56 citations

Effect of perinatal administration of ethanol on the CA1 pyramidal cell of the hippocampus and Purkinje cell of the cerebellum: an ultrastructural survey

1990 • 54 citations

Effects of Prenatal Exposure to Ethanol on the Number of Axons in the Pyramidal Tract of the Rat

1994 • 49 citations

Protein kinase A regulates regulates inhibition of N- and P/Q-type calcium channels by ethanol in PC12 cells.

1997 • 49 citations

A comparative study of ethanol, hypoglycemia, hypoxia and neurotrophic factor interactions with fetal rat hippocampal neurons: a multi-factor in vitro model for developmental ethanol effects

1998 • 45 citations

EFFECTS OF PRENATAL EXPOSURE TO ETHANOL ON THE MATURATION OF THE PYRAMIDAL NEURONS IN THE CEREBRAL CORTEX OF THE GUINEA‐PIG: A QUANTITATIVE GOLGI STUDY

1985 • 40 citations

Alterations in responsiveness to ethanol and neurotrophic substances in fetal septohippocampal neurons following chronic prenatal ethanol exposure

1995 • 39 citations

Quantitative measures of mature neuronal morphology after in utero ethanol exposure.

1984 • 38 citations

Deficiency of essential neurotrophic factors in conditioned media produced by ethanol-exposed cortical astrocytes

1996 • 37 citations

Effect of perinatally administered ethanol on the development of the cerebellar granule cell

1986 • 37 citations

Alcohol inhibits neurite extension and increases N-Myc and c-Myc proteins

1995 • 35 citations

Alcohols synergize with NGF to induce early differentiation of PC12 cells

1991 • 33 citations

Decreased density of synaptic formation in the frontal cortex of neonatal rats exposed to ethanol in utero

1987 • 32 citations

Fetal alcohol effects: Decreased synaptic formations in the field CA3 of fetal hippocampus

1991 • 31 citations

G Proteins Coupled to Phospholipase C: Molecular Targets of Long‐Term Ethanol Exposure

1991 • 30 citations

Chronic alcohol reduces calcium signaling elicited by glutamate receptor stimulation in developing cerebellar neurons

1996 • 29 citations

Immunopanning and Developmental Stage-Specific Primary Culture of Oligodendrocyte Progenitors (O4+GalC−) Directly from Postnatal Rodent Cerebrum

1993 • 29 citations

Effect of Ethanol on the Development and Maturation of Synapses in the Rat Hippocampus: A Quantitative Electron-Microscopic Study

1993 • 29 citations

Correlation between morphological and biochemical effects of ethanol on neuroblast‐enriched cultures derived from three‐day‐old chick embryos

1991 • 28 citations

Ethanol exposure reduces the density of the low-affinity nerve growth factor receptor (p75) on pheochromocytoma (PC12) cells

1996 • 27 citations

Specific effects of ethanol on neurite-promoting proteoglycans of neuronal origin

1990 • 27 citations

Early Events in the Development of Neuronal Polarity In Vitro Are Altered by Ethanol

1998 • 26 citations

Ethanol and voltage- or receptor-mediated increases in cytosolic Ca2+ in brain cells

1992 • 26 citations

Ethanol inhibits NMDA‐induced toxicity and trophism in cultured cerebellar granule cells

1995 • 25 citations

Gi is involved in ethanol inhibition of L-type calcium channels in undifferentiated but not differentiated PC-12 cells.

1995 • 20 citations

Humoral factors derived from glial cells protect cultured neuroblastoma cells against glutamate toxicity

1994 • 15 citations

Neuronal differentiation modifies the effect of ethanol exposure on voltage-dependent calcium channels in NG 108-15 cells

1995 • 15 citations

Ethanol exposure alters the development of serotonergic neurons in chick spinal cord

1996 • 10 citations

Glutamate and cysteinylglycine effects on NMDA receptors: Inhibition by ethanol

1996 • 4 citations