Human Islet Transplantation: Update

Islet Transplantation in Seven Patients with Type 1 Diabetes Mellitus Using a Glucocorticoid-Free Immunosuppressive Regimen

2000 • 5,125 citations

Automated Method for Isolation of Human Pancreatic Islets

1988 • 1,282 citations

CTLA4-Ig and anti-CD40 ligand prevent renal allograft rejection in primates

1997 • 936 citations

METABOLIC COUPLING FACTORS IN PANCREATIC β-CELL SIGNAL TRANSDUCTION

1995 • 529 citations

Vulnerability of Islets in the Immediate Posttransplantation Period: Dynamic Changes in Structure and Function

1996 • 459 citations

Long-term survival and function of intrahepatic islet allografts in rhesus monkeys treated with humanized anti-CD154

1999 • 418 citations

VARIABLES IN ORGAN DONORS THAT AFFECT THE RECOVERY OF HUMAN ISLETS OF LANGERHANS1

1996 • 306 citations

Improved Human Islet Isolation Using a New Enzyme Blend, Liberase

1997 • 303 citations

Pancreatic islet transplantation after upper abdominal exeriteration and liver replacement

1990 • 298 citations

HUMAN ISLET ISOLATION AND ALLOTRANSPLANTATION IN 22 CONSECUTIVE CASES 1, 2

1992 • 258 citations

Long-term follow-up after transplantation of insulin-producing pancreatic islets into patients with Type 1 (insulin-dependent) diabetes mellitus

1992 • 225 citations

Autologous Islet Transplantation to Prevent Diabetes After Pancreatic Resection

1995 • 219 citations

Long-term survival and function of intrahepatic islet allografts in baboons treated with humanized anti-CD154.

1999 • 209 citations

RESULTS OF OUR FIRST NINE INTRAPORTAL ISLET ALLOGRAFTS IN TYPE 1, INSULIN-DEPENDENT DIABETIC PATIENTS

1991 • 199 citations

Normoglycaemia after transplantation of freshly isolated and cryopreserved pancreatic islets in Type 1 (insulin-dependent) diabetes mellitus

1991 • 187 citations

Differential roles of Mac-1+ cells, and CD4+ and CD8+ T lymphocytes in primary nonfunction and classic rejection of islet allografts.

1990 • 184 citations

A SELECTIVE DECREASE IN THE BETA CELL MASS OF HUMAN ISLETS TRANSPLANTED INTO DIABETIC NUDE MICE

1995 • 180 citations

Insulin independence in type I diabetes after transplantation of unpurified islets from single donor with 15-deoxyspergualin

1993 • 162 citations

Human pancreatic islet beta-cell destruction by cytokines involves oxygen free radicals and aldehyde production.

1996 • 160 citations

Natural history of intrahepatic canine islet cell autografts.

1986 • 157 citations

Long-Term Function (6 Years) of Islet Allografts in Type 1 Diabetes

1997 • 147 citations

Autotransplantation of dispersed pancreatic islet tissue combined with total or near-total pancreatectomy for treatment of chronic pancreatitis.

1991 • 145 citations

Interaction of β-Cell Activity and IL-1 Concentration and Exposure Time in Isolated Rat Islets of Langerhans

1989 • 129 citations

Pancreas Transplantation Restores Epinephrine Response and Symptom Recognition During Hypoglycemia in Patients With Long-Standing Type I Diabetes and Autonomic Neuropathy

1997 • 122 citations

Improved survival of intraportal pancreatic islet cell allografts in patients with type-1 diabetes mellitus by refined peritransplant management

1999 • 110 citations

Influence of experimental hyperglycemia on microvascular blood perfusion of pancreatic islet isografts.

1992 • 101 citations

HUMAN PANCREAS PRESERVATION PRIOR TO ISLET ISOLATION

1995 • 99 citations

The effects of chimeric cells following donor bone marrow infusions as detected by PCR-flow assays in kidney transplant recipients.

1997 • 91 citations

Fresh human islet transplantation to replace pancreatic endocrine function in type 1 diabetic patients

1991 • 86 citations

PERIPHERAL BLOOD CHIMERISM IN RENAL ALLOGRAFT RECIPIENTS TRANSFUSED WITH DONOR BONE MARROW1,2

1994 • 83 citations

Metabolic effects of successful intraportal islet transplantation in insulin-dependent diabetes mellitus.

1996 • 73 citations

AN ASSESSMENT OF THE EFFECTS OF CADAVER DONOR BONE MARROW ON KIDNEY ALLOGRAFT RECIPIENT BLOOD CELL CHIMERISM BY A NOVEL TECHNIQUE COMBINING PCR AND FLOW CYTOMETRY1

1996 • 68 citations

IMPROVED GLUCOSE COUNTERREGULATION AND AUTONOMIC SYMPTOMS AFTER INTRAPORTAL ISLET TRANSPLANTS ALONE IN PATIENTS WITH LONG-STANDING TYPE I DIABETES MELLITUS1

1998 • 65 citations

Induction of tolerance by intrathymic inoculation of alloantigen

1996 • 64 citations

Islet cell transplantation in type I diabetes mellitus.

1987 • 46 citations

Successful Long-Term Survival of Pancreatic Islet Allografts in Spontaneous or Pancreatectomy-induced Diabetes in Dogs: Cyclosporine-induced Immune Unresponsiveness

1985 • 46 citations

Sensitization to HLA antigens in islet recipients with failing transplants

1997 • 43 citations

Human Pancreas Preservation Prior to Islet Isolation

2002 • 41 citations

Human islet cell transplantation: New perspectives for an old challenge

1996 • 39 citations

STIMULATION OF CELL REPLICATION IN TRANSPLANTED PANCREATIC ISLETS BY NICOTINAMIDE TREATMENT

1988 • 39 citations

MONOCLONAL ANTIBODIES RECOGNIZING CANINE AND HUMAN Ia-LIKE ANTIGENS

1984 • 30 citations

Effect of Anti-la Antibodies, Culture, and Cyclosporin on Prolongation of Canine Islet Allograft Survival

1987 • 24 citations

Clinical islet transplantation experience of the University of California Islet Transplant Consortium

1995 • 24 citations

Induction of Donor-Specific Tolerance to Rat Islet Allografts by Intrathymic Inoculation of Solubilized Spleen Cell Membrane Antigens

1993 • 24 citations

Ultraviolet Light Immunomodulation of Canine Islets for Prolongation of Allograft Survival

1990 • 24 citations

PREVENTION OF AUTOIMMUNE ISLET ALLOGRAFT DESTRUCTION BY ENGRAFTMENT OF DONOR T CELLS1

1997 • 21 citations

Immunocytochemical Detection and Characterization of Intrahepatic Human Pancreatic Islets after Combined Liver-Islet Allotransplantation

1994 • 13 citations

Coencapsulation of Allogeneic Islets With Allogeneic Sertoli Cells Prolongs Graft Survival Without Systemic Immunosuppression

1998 • 11 citations

PERSISTENCE OF OSCILLATORY INSULIN SECRETION IN DENERVATED ISLET CELL AUTOGRAFTS

1991 • 10 citations

Cellular transplantation and gene therapy

1994 • 3 citations

TOLERANCE INDUCTION TO MULTIPLE DONOR RAT ISLET ALLOGRAFTS BY INTRATHYMIC INOCULATION OF SPLEEN CELL MEMBRANE ANTIGENS

1995 • 2 citations

Is there a risk of sensitizing islet recipients to HLA?

1994 • 2 citations

Deleted Work

1955 • 0 citations