Eradication of human hepatic and pulmonary melanoma metastases in SCID mice by antibody-interleukin 2 fusion proteins.

Use of Tumor-Infiltrating Lymphocytes and Interleukin-2 in the Immunotherapy of Patients with Metastatic Melanoma

1988 • 2,196 citations

Cutaneous Melanoma

1991 • 397 citations

Cytokine gene transfer in tumor inhibition and tumor therapy: where are we now?

1994 • 245 citations

Identifying Strategies for Immune Intervention

1993 • 194 citations

Enhancement of antibody-dependent cytotoxicity with a chimeric anti-GD2 antibody.

1990 • 179 citations

Antibody-targeted interleukin 2 stimulates T-cell killing of autologous tumor cells.

1992 • 179 citations

Targeted vectors for gene therapy

1995 • 163 citations

High-level expression of chimeric antibodies using adapted cDNA variable region cassettes

1989 • 158 citations

A recombinant antibody-interleukin 2 fusion protein suppresses growth of hepatic human neuroblastoma metastases in severe combined immunodeficiency mice.

1994 • 103 citations

Suppression of spontaneous melanoma metastasis in scid mice with an antibody to the epidermal growth factor receptor.

1991 • 98 citations

Biological activity and in vivo clearance of anti-tumor antibody/cytokine fusion proteins

1993 • 95 citations

Priming of tumor-specific T cells in the draining lymph nodes after immunization with interleukin 2-secreting tumor cells: three consecutive stages may be required for successful tumor vaccination.

1995 • 94 citations

Relapse in the central nervous system in melanoma patients successfully treated with biomodulators.

1989 • 89 citations

Interleukin-2 in cancer treatment: Disappointing or (still) promising? A review

1993 • 86 citations

Inhibition of Human Colon Cancer Growth by Antibody-Directed Human LAK Cells in SCID Mice

1993 • 86 citations

Serum half-life and tumor localization of a chimeric antibody deleted of the CH2 domain and directed against the disialoganglioside GD2.

1990 • 83 citations

Treatment of Neuroblastoma Patients with Antiganglioside GD2 Antibody plus Interleukin-2 Induces Antibody-Dependent Cellular Cytotoxicity Against Neuroblastoma Detected In Vitro

1994 • 73 citations

Genetic construction and characterization of a fusion protein consisting of a chimeric F(ab') with specificity for carcinomas and human IL-2.

1991 • 55 citations

Expression of Genetically Engineered Immunoconjugates of Lymphotoxin and a Chimeric Anti-Ganglioside GD2 Antibody

1991 • 55 citations

Recent developments in immunotoxin therapy

1994 • 48 citations

A multicenter phase II clinical trial using dacarbazine and continuous infusion lnterleukin-2 for metastatic melanoma. Clinical data and immunomonitoring

1995 • 47 citations

A recombinant single chain antibody interleukin-2 fusion protein

1993 • 40 citations

Targeting cancer with radiolabeled antibodies

1995 • 38 citations

Cytokines and clinical gene therapy

1995 • 37 citations

Recent developments in the radioimmunotherapy of cancer

1994 • 31 citations

Molecular Pathology -- Detection of Neoplasia

1994 • 30 citations

Mechanisms of cellular cytotoxicity mediated by a recombinant antibody-IL2 fusion protein against human melanoma cells

1993 • 19 citations

Applications of monoclonal antibodies in clinical oncology

1994 • 18 citations

Cancer therapy with tumor-infiltrating lymphocytes: evaluation of potential and limitations.

1991 • 6 citations