Comparative Activity of Melarsoprol and Arsenic Trioxide in Chronic B-Cell Leukemia Lines

Use of Arsenic Trioxide (As2O3 ) in the Treatment of Acute Promyelocytic Leukemia (APL): II. Clinical Efficacy and Pharmacokinetics in Relapsed Patients

1997 • 1,431 citations

In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins

1996 • 843 citations

Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL) : I. As2O3 exerts dose-dependent dual effects on APL cells

1997 • 808 citations

bcl-2 gene hypomethylation and high-level expression in B-cell chronic lymphocytic leukemia

1993 • 660 citations

Guidelines for clinical protocols for chronic lymphocytic leukemia: Recommendations of the national cancer institute‐sponsored working group

1988 • 415 citations

The cell cycle related differences in susceptibility of HL-60 cells to apoptosis induced by various antitumor agents.

1993 • 403 citations

Interleukin 4 protects chronic lymphocytic leukemic B cells from death by apoptosis and upregulates Bcl-2 expression.

1992 • 366 citations

B-cell chronic lymphocytic leukemia: present status and future directions. French Cooperative Group on CLL

1991 • 298 citations

Induction of apoptotic cell death in chronic lymphocytic leukemia by 2- chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine

1993 • 283 citations

Inhibition of DNA Fragmentation in Thymocytes and Isolated Thymocyte Nuclei by Agents That Stimulate Protein Kinase C

1989 • 276 citations

Induction of apoptotic cell death in chronic lymphocytic leukemia by 2- chloro-2'-deoxyadenosine and 9-beta-D-arabinosyl-2-fluoroadenine

1993 • 226 citations

B-cell chronic lymphocytic leukemia: present status and future directions. French Cooperative Group on CLL

1991 • 218 citations

Basic fibroblast growth factor (bFGF) upregulates the expression of bcl-2 in B cell chronic lymphocytic leukemia cell lines resulting in delaying apoptosis

1997 • 177 citations

Overexpression of cyclin D2 in chronic B-cell malignancies

1995 • 154 citations

Mutations of the p53 gene in B-cell chronic lymphocytic leukemia: a report on 39 cases with cytogenetic analysis.

1992 • 147 citations

Mel B in the Treatment of Human Trypanosomiasis

1949 • 121 citations

Complete and Reversible Inhibition of NADPH Oxidase in Human Neutrophils by Phenylarsine Oxide at a Step Distal to Membrane Translocation of the Enzyme Subunits

1995 • 91 citations

Two new cell lines from B‐prolymphocytic leukaemia: Characterization by morphology, immunological markers, karyotype and Ig gene rearrangement

1986 • 69 citations

Retinoblastoma gene deletions in b‐cell chronic lymphocytic leukemia

1992 • 67 citations

Epstein-Barr virus (EBV) can immortalize B-cll cells activated by cytokines.

1994 • 67 citations

Autocrine and paracrine growth loops in chronic lymphocytic leukemia.

1993 • 55 citations

Mechanisms of metalloregulation of an anion-translocating ATPase

1995 • 53 citations

Establishment of a human B-CLL xenograft model: utility as a preclinical therapeutic model.

1996 • 41 citations

The establishment of cell lines from chronic B cell leukaemias: evidence of leukaemic origin by karyotypic abnormalities and Ig gene rearrangement.

1988 • 39 citations

CHRONIC ARSENICAL POISONING DURING THE TREATMENT OF CHRONIC MYELOID LEUKEMIA

1937 • 31 citations

Differential susceptibility of filarial and human erythrocyte glutathione reductase to inhibition by the trivalent organic arsenical melarsen oxide

1995 • 20 citations

The Active Form of Tryparsamide, TPB, in the Treatment of Human Trypanosomiasis 1,2

1949 • 3 citations

INFLUENCE OF BAL ON THE TOXICITY AND CHEMOTHERAPEUTIC ACTIVITY OF MAPHARSEN

1948 • 2 citations