How frailty models can be used for evaluating longevity limits: Taking advantage of an interdisciplinary approach

Introduction to Quantitative Genetics.

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Analysis of Survival Data

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Analysis of Survival Data.

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Aging, Natural Death, and the Compression of Morbidity

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The impact of heterogeneity in individual frailty on the dynamics of mortality

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A model for association in bivariate life tables and its application in epidemiological studies of familial tendency in chronic disease incidence

1978 • 1,954 citations

Regression Analysis of Multivariate Incomplete Failure Time Data by Modeling Marginal Distributions

1989 • 1,774 citations

Mathematical Population Genetics

2006 • 1,764 citations

An Introduction to Quantitative Genetics

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Genetic and Environmental Influences on Premature Death in Adult Adoptees

1988 • 814 citations

Heterogeneity's Ruses: Some Surprising Effects of Selection on Population Dynamics

1985 • 810 citations

Bivariate Survival Models Induced by Frailties

1989 • 793 citations

Mathematical Population Genetics.

1980 • 756 citations

Behavioral genetics, a primer

1980 • 722 citations

The Genetic Structure of Populations

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Econometric duration analysis

1984 • 640 citations

In Search of Methuselah: Estimating the Upper Limits to Human Longevity

1990 • 623 citations

Multivariate Generalizations of the Proportional Hazards Model

1985 • 595 citations

A class of multivanate failure time distributions

1986 • 592 citations

Cox regression analysis of multivariate failure time data: The marginal approach

1994 • 580 citations

A counting process approach to maximum likelihood estimation in frailty models

1992 • 551 citations

Models for the joint effect of genotype and environment on liability to psychiatric illness

1986 • 530 citations

A Model for Association in Bivariate Survival Data

1982 • 461 citations

On the Law of Mortality and the Construction of Annuity Tables

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The biology of life span: A quantitative approach

1992 • 438 citations

The Compression of Morbidity

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Age-Specific Incidence and Prevalence: A Statistical Perspective

1991 • 394 citations

Longevity Is Moderately Heritable in a Sample of Danish Twins Born 1870-1880

1993 • 359 citations

Epidemiology of Alzheimer's Disease

1992 • 340 citations

Research With Twins: The Concept of Emergenesis

1982 • 339 citations

The Compression of Morbidity: Near or Far?

1989 • 335 citations

Heterogeneity, omitted variable bias, and duration dependence

1985 • 328 citations

Onset of Major Depression in Early Adulthood

1984 • 324 citations

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1978 • 314 citations

Mortality among twins after age 6: fetal origins hypothesis versus twin method

1995 • 296 citations

A Class of Multivariate Failure Time Distributions

1986 • 281 citations

Outline of Genetic Epidemiology.

1983 • 247 citations

Twin studies in medical research: can they tell us whether diseases are genetically determined?

1993 • 245 citations

Sociological Methodology 1983-1984

1985 • 238 citations

Modelling Paired Survival Data with Covariates

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A Family of Distributions for Modelling Non-Elliptically Symmetric Multivariate Data

1981 • 235 citations

The biology of life span—A quantitative approach

1992 • 233 citations

The Study of Human Twins in Medical Research

1984 • 211 citations

The Compression of Morbidity

1983 • 198 citations

Familial Patterns in Ischaemic Heart Disease

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The Danish Twin Register

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Correlated individual frailty: An advantageous approach to survival analysis of bivariate data

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Prospective longitudinal research : an empirical basis for the primary prevention of psychosocial disorders

1981 • 184 citations

Recent Trends in Mortality Analysis.

1985 • 178 citations

The new genetics and clinical practice

1982 • 178 citations

Compression of Mortality: Myth or Reality?

1984 • 176 citations

The Deviant Dynamics of Death in Heterogeneous Populations

1985 • 172 citations

Estimating a Multivariate Proportional Hazards Model for Clustered Data Using the EM Algorithm, with an Application to Child Survival in Guatemala

1992 • 164 citations

Semiparametric inference in a model for association in bivanate survival data

1986 • 139 citations

A Genetic Study of Human Breast Cancer<xref ref-type="fn" rid="FN1">1</xref><xref ref-type="fn" rid="FN2">2</xref>

1972 • 136 citations

Age at Onset in Schizophrenia

1987 • 135 citations

Estimating genetic influences on the age‐at‐menarche: A survival analysis approach

1991 • 127 citations

Use of Sibling Data to Estimate Family Mortality Effects in Guatemala

1993 • 125 citations

A comparison of frailty models for multivariate survival data

1995 • 121 citations

Measuring the Similarities between the Lifetimes of Adult Danish Twins Born between 1881–1930

1992 • 112 citations

Genetic analysis of durations: Correlated frailty model applied to survival of Danish twins

1995 • 109 citations

Inherited frailty and longevity.

1988 • 107 citations

Inherited frailty and longevity

1988 • 107 citations

A genetic model for age at onset in Huntington disease.

1985 • 92 citations

The New Genetics and Clinical Practice

1991 • 91 citations

Time-Dependent Association Measures for Bivariate Survival Distributions

1992 • 90 citations

THE USE OF LIFE TABLES AND SURVIVAL ANALYSIS IN TESTING GENETIC HYPOTHESES, WITH AN APPLICATION TO ALZHEIMER'S DISEASE1

1983 • 77 citations

ON THE INHERITANCE OF THE DURATION OF LIFE, AND ON THE INTENSITY OF NATURAL SELECTION IN MAN.

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Time-varying Covariates in Models of Human Mortality and Aging: Multidimensional Generalizations of the Gompertz

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The ancestry of the long-lived

1934 • 68 citations

Longevity of Parents and Grandparents in Relation to Coronary Heart Disease and Associated Variables

1971 • 64 citations

Fertility and longevity in twins, sibs, and parents of twins

1978 • 64 citations

Biological and Social Aspects of Mortality and the Length of Life.

1983 • 63 citations

The Biodemography of Variation in Human Frailty

1990 • 62 citations

Demographic Perspectives on Human Senescence

1994 • 62 citations

The familial component in longevity—A study of offspring of nonagenarians: III. Intrafamilial studies

1978 • 61 citations

How long can humans live? Lower bound for biological limit of human longevity calculated from Danish twin data using correlated frailty model

1995 • 55 citations

Semiparametric Inference in a Model for Association in Bivariate Survival Data

1986 • 55 citations

Studies of familial alcoholism: a review.

1984 • 53 citations

Future outlook for mortality decline in the world.

1978 • 53 citations

Data for the problem of evolution in man. II. A first study of the inheritance of longevity and the selective death-rate in man

1900 • 52 citations

TWIN STUDIES ON AGING AND LONGEVITY*

1948 • 52 citations

TWIN STUDIES ON SENESCENCE

1949 • 46 citations

Debilitation's aftermath: Stochastic process models of mortality

1988 • 46 citations

Familial factors in early deaths: Twins followed 30 years to ages 51–61 in 1978

1981 • 46 citations

Estimating Random Effects In the Framingham Heart Study

1992 • 44 citations

Transmissible and non-transmissible neurodegenerative disease: similarities in age of onset and genetics in relation to aetiology

1986 • 39 citations

Analyzing the relationship between age at onset and risk to relatives.

1989 • 34 citations

Genetics of Longevity in Man

1978 • 32 citations

Prospects for Detecting Genotype × Environment Interactions in Twins with Breast Cancer

1987 • 30 citations

The relationship of age of onset in unipolar affective disorder to risk of alcoholism and depression in parents

1977 • 29 citations

Bivariate survival models for analysis of genetic and environmental effects in twins

1990 • 27 citations

Estimating genetic parameters of survival distributions: A multifactorial model

1988 • 26 citations

Is longevity inherited?

1981 • 26 citations

Survival of related individuals: An extension of some fundamental results of heterogeneity analysis

1995 • 25 citations

Familial Factors in Mortality with Control of Epidemiological Covariables. Swedish Twins Born 1886-1925

1984 • 20 citations

The use of survival time models with nonproportional hazard functions to investigate age of onset in family studies

1986 • 19 citations

Longevity: Some familial correlates

1980 • 18 citations

Survival Analysis in Genetics: Danish Twin Data Applied To a Gerontological Question

1992 • 18 citations

The relationship of myocardial infarction to parental mortality and longevity

1968 • 14 citations

Application of survival analysis to the inception of dementia

1986 • 12 citations

Survival Analysis: Lessons from Quantitative Genetics

1987 • 6 citations

Deleted Work

1955 • 0 citations