Alpha-synuclein immunoreactivity of huntingtin polyglutamine aggregates in striatum and cortex of Huntington's disease patients and transgenic mouse models

Mutation in the α-Synuclein Gene Identified in Families with Parkinson's Disease

1997 • 7,814 citations

The synucleins: a family of proteins involved in synaptic function, plasticity, neurodegeneration and disease

1998 • 756 citations

Altered brain neurotransmitter receptors in transgenic mice expressing a portion of an abnormal human Huntington disease gene

1998 • 509 citations

Long glutamine tracts cause nuclear localization of a novel form of huntingtin in medium spiny striatal neurons in HdhQ92 and HdhQ111 knock-in mice

2000 • 456 citations

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA

1998 • 401 citations

Wild-Type and Mutant Huntingtins Function in Vesicle Trafficking in the Secretory and Endocytic Pathways

1998 • 322 citations

Impaired Synaptic Plasticity in Mice Carrying the Huntington's Disease Mutation

1999 • 231 citations

Recent advances in understanding the pathogenesis of Huntington's disease

1999 • 204 citations

Ultrastructural localization and progressive formation of neuropil aggregates in Huntington's disease transgenic mice

1999 • 201 citations

A molecular investigation of true dominance in Huntington's disease

1999 • 154 citations

Fast transport and retrograde movement of huntingtin and HAP 1 in axons

1997 • 137 citations

Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease

1998 • 131 citations

Neuronal degeneration in the basal ganglia and loss of pallido-subthalamic synapses in mice with targeted disruption of the Huntington's disease gene

1999 • 86 citations

Partial characterisation of murine huntingtin and apparent variations in the subcellular localisation of huntingtin in human, mouse and rat brain

1996 • 85 citations

α-Synuclein overexpression promotes aggregation of mutant huntingtin

2000 • 84 citations

Transgenic mice expressing mutated full-length HD cDNA: a paradigm for locomotor changes and selective neuronal loss in Huntington's disease

1999 • 73 citations

Huntington's disease gene product, huntingtin, associates with microtubules in vitro

1997 • 66 citations

α-Synuclein overexpression promotes aggregation of mutant huntingtin

2000 • 11 citations