Abnormal insulin secretion and glucose metabolism in pancreatic islets from the spontaneously diabetic GK rat

Coated Charcoal Immunoassay of Insulin

1965 • 3,018 citations

An improved fluorometric assay for DNA

1971 • 997 citations

β-cells in type II diabetes mellitus

1991 • 582 citations

The stimulus-secretion coupling of glucose-induced insulin release

1979 • 420 citations

The pentose cycle and insulin release in mouse pancreatic islets

1972 • 304 citations

β-Cell Insensitivity to Glucose in the GK Rat, a Spontaneous Nonobese Model for Type II Diabetes

1991 • 259 citations

Inhibition of ATP-regulated K+ channels precedes depolarization-induced increase in cytoplasmic free Ca2+ concentration in pancreatic beta-cells.

1987 • 173 citations

Aspects of the Pathogenesis of Type 2 Diabetes*

1984 • 155 citations

Experimental reduction of B‐cell mass: Implications for the pathogenesis of diabetes

1986 • 134 citations

Etude expérimentale d'un nouveau sulfamide hypoglycémiant particulièrement actif, le HB 419 ou glibenclamide

1969 • 127 citations

Etude expérimentale d'un nouveau sulfamide hypoglycémiant particulièrement actif, le HB 419 ou glibenclamide

1969 • 122 citations

Impaired insulin secretion in the spontaneous diabetes rats.

1982 • 90 citations

Impairment of Glycerol Phosphate Shuttle in Islets From Rats With Diabetes Induced by Neonatal Streptozocin

1991 • 76 citations

Relation of Insulin Deficiency to Impaired Insulin Action in NIDDM Adult Rats Given Streptozocin as Neonates

1989 • 64 citations

Glucose Cycling in Islets From Healthy and Diabetic Rats

1990 • 51 citations

Insulin Production and Glucose Metabolism in Isolated Pancreatic Islets of Rats With NIDDM

1988 • 50 citations

B cell insensitivity in a rat model of non-insulin-dependent diabetes. Evidence for a rapidly reversible effect of previous hyperglycemia.

1987 • 47 citations

Pathogenesis of non-insulin dependent diabetes mellitus

1988 • 36 citations

The cytoplasmic Ca²⁺ response to glucose as an indicator of impairment of the pancreatic β‐cell function

1990 • 34 citations

Elevated Proinsulin Biosynthesis In Vitro from a Rat Model of Non-insulin-dependent Diabetes Mellitus

1983 • 27 citations

The Anomeric Malaise: A Manifestation of B-Cell Glucotoxicity

1991 • 26 citations

Differences in long-term effects of l-glutamine and d-glucose on insulin release from rat pancreatic islets

1986 • 25 citations

Neonatal streptozotocin injection: A model of glucotoxicity?

1991 • 12 citations

Aspects of insulin release in NIDDM

1993 • 1 citations