Retrograde, trans-synaptic and transneuronal transport of fragment C of tetanus toxin by sympathetic preganglionic neurons

Estimation of nuclear population from microtome sections

1946 • 4,378 citations

THE AUTONOMIC NERVOUS SYSTEM

1903 • 1,674 citations

Central regulation of autonomic functions

1991 • 1,124 citations

Intracellular transport in neurons.

1980 • 1,011 citations

Spinal termination of functionally identified primary afferent neurons with slowly conducting myelinated fibers

1979 • 785 citations

Central Projections of Identified, Unmyelinated (C) Afferent Fibers Innervating Mammalian Skin

1986 • 670 citations

A general pattern of CNS innervation of the sympathetic outflow demonstrated by transneuronal pseudorabies viral infections

1989 • 574 citations

CNS cell groups regulating the sympathetic outflow to adrenal gland as revealed by transneuronal cell body labelling with pseudorabies virus

1989 • 484 citations

The action of tetanus toxin on the inhibition of motoneurones

1957 • 323 citations

Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons

1975 • 277 citations

Autonomic neurons in the spinal cord of the rhesus monkey: A correlation of the findings of cytoarchitectonics and sympathectomy with fiber degeneration following dorsal rhizotomy

1972 • 272 citations

Bacterial Protein Toxins

1985 • 237 citations

Selective retrograde transsynaptic transfer of a protein, tetanus toxin, subsequent to its retrograde axonal transport

1979 • 229 citations

Tetanus Toxin: Direct Evidence for Retrograde Intraaxonal Transport

1975 • 224 citations

Colin Bonnet McKerrow.

1972 • 222 citations

INVOLVEMENT OF THE SYMPATHETIC NERVOUS SYSTEM IN TETANUS

1968 • 215 citations

Tetanus toxin and spinal inhibition

1968 • 191 citations

How does tetanus toxin act?

1981 • 189 citations

Retrograde axonal transport of specific macromolecules as a tool for characterizing nerve terminal membranes

1979 • 183 citations

Intracellularly injected tetanus toxin inhibits exocytosis in bovine adrenal chromaffin cells

1986 • 183 citations

Structure of tetanus toxin. I. Breakdown of the toxin molecule and discrimination between polypeptide fragments.

1977 • 163 citations

Electron microscopic evidence for a transsynaptic migration of tetanus toxin in spinal cord motoneurons: An autoradiographic and morphometric study

1976 • 147 citations

Tetanus toxin and the synaptic release of GABA

1973 • 136 citations

Selective trans-synaptic migration of tetanus toxin after retrograde axonal transport in peripheral sympathetic nerves: A comparison with the nerve growth factor

1977 • 134 citations

Relation of animal size to convergence, divergence, and neuronal number in peripheral sympathetic pathways

1986 • 133 citations

AN ANTIGENIC POLYPEPTIDE FRAGMENT ISOLATED FROM TETANUS TOXIN: CHEMICAL CHARACTERIZATION, BINDING TO GANGLIOSIDES AND RETROGRADE AXONAL TRANSPORT IN VARIOUS NEURON SYSTEMS

1977 • 124 citations

Spinal afferent processing

1987 • 121 citations

Intraaxonal and extraaxonal transport of 125I-tetanus toxin in early local tetanus

1975 • 103 citations

Transsynaptic retrograde transport of fragment C of tetanus toxin demonstrated by immunohistochemical localization

1986 • 97 citations

Cardiovascular Control in Spinal Man

1988 • 95 citations

Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides.

1980 • 89 citations

Tetanus toxin: evidence for binding at presynaptic nerve endings

1977 • 86 citations

Differential effects of tetanus toxin on inhibitory and excitatory synaptic transmission in mammalian spinal cord neurons in culture: a presynaptic locus of action for tetanus toxin

1987 • 86 citations

Autonomic Nervous System

1971 • 83 citations

At least three sequential steps are involved in the tetanus toxin-induced block of neuromuscular transmission

1981 • 82 citations

Tetanus neurotoxin

1982 • 81 citations

Sympathetic Preganglionic Neurons: Cytoarchitecture, Ultrastructure, and Biophysical Properties

1990 • 64 citations

Retrograde transneuronal transfer of the C-fragment of tetanus toxin

1987 • 64 citations

Tetanus Toxin in Dissociated Spinal Cord Cultures: Long‐Term Characterization of Form and Action

1986 • 61 citations

Retrograde transneuronal transport properties of fragment C of tetanus toxin

1990 • 56 citations

Characterization of fragment C and tetanus toxin binding to rat brain membranes.

1981 • 55 citations

Quantitative comparison between tetanus toxin, some fragments and toxoid for binding and axonal transport in the rat

1986 • 50 citations

Central and Peripheral Mechanisms of Cardiovascular Regulation

1986 • 50 citations

Motoneuron Uptake From the Circulation of the Binding Fragment of Tetanus Toxin

1988 • 46 citations

Retrograde transport of tetanus toxin through a chain of two neurons

1979 • 44 citations

Light microscopic and ultrastructural localization of GABA-like immunoreactive input to retrogradely labeled sympathetic preganglionic neurons

1989 • 44 citations

Histoautoradiographic localisation of 125I-labeled tetanus toxin in rat spinal cord

1973 • 43 citations

Interaction of labelled tetanus toxin with substructures of rat spinal cord in vivo

1973 • 43 citations

Effect of tetanus toxin on the excitatory and the inhibitory post‐synaptic potentials in the cat motoneurone.

1983 • 42 citations

Current topics in tetanus

1979 • 41 citations

Papain-derived fragment IIc of tetanus toxin: its binding to isolated synaptic membranes and retrograde axonal transport

1981 • 41 citations

Light microscopic observations on the morphology of sympathetic preganglionic neurons in the pigeon, Columba livia

1987 • 39 citations

Transsynaptic retrograde labeling in the oculomotor system of the monkey with [125I]tetanus toxin BIIb fragment

1981 • 39 citations

Tetanus toxin induced actions on spinal Renshaw cells and Ia-inhibitory interneurones during development of local tetanus in the cat

1977 • 38 citations

Pharmacological experiments on the binding and internalization of the 50,000 dalton carboxyterminus of tetanus toxin at the cholinergic neuromuscular junction.

1985 • 33 citations

Fragment C of tetanus toxin antagonizes the neuromuscular blocking properties of native tetanus toxin.

1984 • 33 citations

Botulinum toxin and tetanus toxin recognize similar membrane determinants

1984 • 31 citations

Tetanus toxin: Retrograde axonal transport of systemically administered toxin

1977 • 30 citations

Spinal terminal fields of dorsal root fibers in the pigeon (Columba livia)

1975 • 30 citations

Dorsal Horn Neurons and Their Sensory Inputs

1986 • 28 citations

Avian sympathetic cardiac fibers and their cells of origin: anatomical and electrophysiological characteristics

1977 • 27 citations

Metabolic fate of 125I-tetanus toxin in the spinal cord of rats and cats with early local tetanus

1977 • 27 citations

Anatomical and physiological characterization of avian sympathetic cardiac afferents

1977 • 26 citations

The action of tetanus toxin on preganglionic sympathetic reflex discharges

1973 • 23 citations

Spinal Factors in Sympathetic Regulation

1986 • 22 citations

The Structure of Tetanus Toxin

1989 • 22 citations

Peripheral Actions of Tetanus Toxin

1989 • 21 citations

Neural Control of the Avian Heart

1980 • 21 citations

Clostridial Toxins and the Central Nervous System: Studies on In Situ Tissues

1989 • 21 citations

Botulinum neurotoxin and tetanus toxin

1990 • 19 citations

Immunocytochemical localization of tetanus toxin to synapses of spinal cord

1981 • 17 citations

Potentials of spinal motoneurons in cats with experimental tetanus

1970 • 16 citations

The involvement of the sympathetic nervous system in tetanus

1979 • 15 citations

Histoautoradiography of central nervous system in rats with generalized tetanus due to 125I-toxin

1977 • 15 citations

Electrical excitability of motoneurones in early local tetanus

1979 • 14 citations

Dysfunction of the sympathetic nervous system in tetanus

1979 • 12 citations

Studies on the sympathetic nervous system in tetanus

1973 • 11 citations

Axoplasmic Transport and Transynaptic Movement of Tetanus Toxin

1989 • 9 citations

Entry of Bacterial Toxins into Mammalian Cells

1989 • 6 citations