Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site

The CCP4 suite: programs for protein crystallography

1994 • 17,203 citations

MOLSCRIPT: a program to produce both detailed and schematic plots of protein structures

1991 • 14,222 citations

Improved methods for building protein models in electron density maps and the location of errors in these models

1991 • 12,831 citations

AMoRe: an automated package for molecular replacement

1994 • 4,990 citations

Free R value: a novel statistical quantity for assessing the accuracy of crystal structures

1992 • 3,863 citations

Automatic processing of rotation diffraction data from crystals of initially unknown symmetry and cell constants

1993 • 3,564 citations

Accurate bond and angle parameters for X-ray protein structure refinement

1991 • 2,467 citations

Crystallographic R Factor Refinement by Molecular Dynamics

1987 • 1,982 citations

Evaluation of single-crystal X-ray diffraction data from a position-sensitive detector

1988 • 1,516 citations

Reduction of Ribonucleotides

1979 • 1,170 citations

Crystal structure of a bacterial non-haem iron hydroxylase that catalyses the biological oxidation of methane

1993 • 904 citations

An efficient general-purpose least-squares refinement program for macromolecular structures

1987 • 871 citations

Three-dimensional structure of the free radical protein of ribonucleotide reductase

1990 • 833 citations

Structure and Function of the Escherichia coli Ribonucleotide Reductase Protein R2

1993 • 462 citations

Iron carriers and iron proteins

1989 • 439 citations

BIOCHEMISTRY OF THE SOLUBLE METHANE MONOOXYGENASE

1994 • 396 citations

Iron and Free Radical in Ribonucleotide Reductase

1973 • 364 citations

Mechanism of Assembly of the Tyrosyl Radical-Dinuclear Iron Cluster Cofactor of Ribonucleotide Reductase

1991 • 356 citations

Geometry of the soluble methane monooxygenase catalytic diiron center in two oxidation states

1995 • 337 citations

Ribonucleotide reductases: amazing and confusing.

1990 • 288 citations

Di-iron—carboxylate proteins

1995 • 243 citations

Modeling the Oxygen Activation Chemistry of Methane Monooxygenase and Ribonucleotide Reductase

1996 • 222 citations

Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactor of E. Coli Ribonucleotide Reductase: 1. Moessbauer Characterization of the Diferric Radical Precursor

1994 • 204 citations

NAD(P)H:flavin oxidoreductase of Escherichia coli. A ferric iron reductase participating in the generation of the free radical of ribonucleotide reductase.

1987 • 190 citations

Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactorof E. coli Ribonucleotide Reductase. 3. Kinetics of the Limiting Fe2+ Reaction by Optical, EPR, and Moessbauer Spectroscopies

1994 • 160 citations

Complex formation between the protein components of methane monooxygenase from Methylosinus trichosporium OB3b. Identification of sites of component interaction.

1991 • 151 citations

Substitution of manganese for iron in ribonucleotide reductase from Escherichia coli. Spectroscopic and crystallographic characterization.

1992 • 128 citations

Gating Effects of Component B on Oxygen Activation by the Methane Monooxygenase Hydroxylase Component

1995 • 120 citations

Mechanism of Assembly of the Tyrosyl Radical-Diiron(III) Cofactor of E. coli Ribonucleotide Reductase. 2. Kinetics of The Excess Fe2+ Reaction by Optical, EPR, and Moessbauer Spectroscopies

1994 • 120 citations

Mössbauer and EPR studies of the binuclear iron center in ribonucleotide reductase from Escherichia coli

1989 • 118 citations

Characterization of the flavin reductase gene (fre) of Escherichia coli and construction of a plasmid for overproduction of the enzyme

1991 • 116 citations

A substrate radical intermediate in the reaction between ribonucleotide reductase from Escherichia coli and 2'-azido-2'-deoxynucleoside diphosphates.

1983 • 108 citations

Evidence by Site-Directed Mutagenesis Supports Long-Range Electron Transfer in Mouse Ribonucleotide Reductase

1995 • 107 citations

The Redox Centers of Ribonucleotide Reductase of Escherichia coli

1992 • 98 citations

Electron Paramagnetic Resonance Study of the Mixed-Valent Diiron Center in Escherichia coli Ribonucleotide Reductase Produced by Reduction of Radical-Free Protein R2 at 77 K

1994 • 94 citations

Spectroscopic studies of the coupled binuclear non-heme iron active site in the fully reduced hydroxylase component of methane monooxygenase: comparison to deoxy and deoxy-azide hemerythrin

1993 • 91 citations

Reduced forms of the iron-containing small subunit of ribonucleotide reductase from Escherichia coli

1989 • 82 citations

Enzymatic Regulation of the Radical Content of the Small Subunit of Escherichia coli Ribonucleotide Reductase Involving Reduction of Its Redox Centers

1989 • 80 citations

Reaction of NO with the Reduced R2 Protein of Ribonucleotide Reductase from Escherichia coli

1995 • 80 citations

Tyrosyl free radical formation in the small subunit of mouse ribonucleotide reductase.

1990 • 73 citations

Unusual clustering of carboxyl side chains in the core of iron-free ribonucleotide reductase

1993 • 71 citations

Ribonucleotide Reductases

1990 • 71 citations

Activation of the iron-containing B2 protein of ribonucleotide reductase by hydrogen peroxide

1990 • 69 citations

The active site structure of methane monooxygenase is closely related to the binuclear iron center of ribonucleotide reductase

1992 • 64 citations

Circular Dichroism and Magnetic Circular Dichroism Studies of the Fully Reduced Binuclear Non-Heme Iron Active Site in the Escherichia coli R2 Subunit of Ribonucleoside Diphosphate Reductase

1995 • 53 citations

Electron Transfer Properties of the R2 Protein of Ribonucleotide Reductase from Escherichia coli

1995 • 44 citations

Reduction of the Fe(III)-tyrosyl radical center of Escherichia coli ribonucleotide reductase by dithiothreitol.

1990 • 38 citations

Superoxide dismutase participates in the enzymatic formation of the tyrosine radical of ribonucleotide reductase from Escherichia coli.

1986 • 36 citations

Structure of Ribonucleotide Reductase from Escherichia coli

1995 • 36 citations

New crystal forms of the small subunit of ribonucleotide reductase from Escherichia coli

1989 • 30 citations

A mixed valence form of the iron cluster in the B2 protein of ribonucleotide reductase from Escherichia coli

1991 • 27 citations

The conserved serine 211 is essential for reduction of the dinuclear iron center in protein R2 of Escherichia coli ribonucleotide reductase.

1994 • 19 citations

Reduction of the Small Subunit of Ribonucleotide Reductase by Diimide: Evidence for the Formation of the Mixed‐Valence Fe^{<scp>II</scp>}Fe^{<scp>III</scp>} center

1991 • 14 citations

Carboxylate Shifts in the Active Site of the Hydroxylase Component of Soluble Methane Monooxygenase from Methylococcus capsulatus (Bath)

1996 • 12 citations

Intrinsic inequalities among the partial intensities of the short-range-order diffuse scattering from a disordered ternary alloy

1987 • 9 citations

Deleted Work

1955 • 0 citations