Alternative splicing: increasing diversity in the proteomic world

The Genome Sequence of Drosophila melanogaster

2000 • 5,882 citations

Genome Sequence of the Nematode C. elegans : A Platform for Investigating Biology

1998 • 3,683 citations

Functional genomic analysis of C. elegans chromosome I by systematic RNA interference

2000 • 1,767 citations

Neuroligin Expressed in Nonneuronal Cells Triggers Presynaptic Development in Contacting Axons

2000 • 1,176 citations

Drosophila Dscam Is an Axon Guidance Receptor Exhibiting Extraordinary Molecular Diversity

2000 • 1,067 citations

Alternative pre-mRNA splicing: the logic of combinatorial control

2000 • 892 citations

Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III

2000 • 867 citations

Exonic splicing enhancers: mechanism of action, diversity and role in human genetic diseases

2000 • 689 citations

ALTERNATIVE SPLICING OF PRE-mRNA: Developmental Consequences and Mechanisms of Regulation

1998 • 644 citations

Neuroligin 1: A splice site-specific ligand for β-neurexins

1995 • 635 citations

Frequent Alternative Splicing of Human Genes

1999 • 553 citations

Molecular analysis of the para locus, a sodium channel gene in Drosophila

1989 • 501 citations

mRNA surveillance by the Caenorhabditis elegans smg genes.

1993 • 459 citations

Cartography of neurexins: More than 1000 isoforms generated by alternative splicing and expressed in distinct subsets of neurons

1995 • 446 citations

Nova-1 Regulates Neuron-Specific Alternative Splicing and Is Essential for Neuronal Viability

2000 • 415 citations

A-to-I Pre-mRNA Editing in Drosophila Is Primarily Involved in Adult Nervous System Function and Integrity

2000 • 389 citations

Analysis of expressed sequence tags indicates 35,000 human genes

2000 • 367 citations

Neurexins: Three genes and 1001 products

1998 • 359 citations

Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequence

2000 • 324 citations

Conservation, Regulation, Synteny, and Introns in a Large-scale C. briggsae–C. elegans Genomic Alignment

2000 • 290 citations

The Regulation of Splice-Site Selection, and Its Role in Human Disease

1997 • 277 citations

Quality Control Mechanisms During Translation

1999 • 217 citations

Shotgun sequencing of the human transcriptome with ORF expressed sequence tags

2000 • 217 citations

Mechanisms of mRNA Surveillance in Eukaryotes

1999 • 212 citations

Distribution of Ca2+-Activated K+ Channel Isoforms along the Tonotopic Gradient of the Chicken's Cochlea

1997 • 203 citations

Unproductively spliced ribosomal protein mRNAs are natural targets of mRNA surveillance in C. elegans

2000 • 187 citations

A Molecular Mechanism for Electrical Tuning of Cochlear Hair Cells

1999 • 183 citations

The mlenapts RNA Helicase Mutation in Drosophila Results in a Splicing Catastrophe of the para Na + Channel Transcript in a Region of RNA Editing

2000 • 177 citations

Test of intron predictions reveals novel splice sites, alternatively spliced mRNAs and new introns in meiotically regulated genes of yeast

2000 • 173 citations

Differential Distribution of Ca2+-Activated K+ Channel Splice Variants among Hair Cells along the Tonotopic Axis of the Chick Cochlea

1997 • 165 citations

The Making of Neurexins

1998 • 155 citations

Alternative splicing of human genes: more the rule than the exception?

1999 • 125 citations

RNA Editing of the DrosophilaparaNa+ Channel Transcript: Evolutionary Conservation and Developmental Regulation

2000 • 111 citations

Neurexins Are Functional α-Latrotoxin Receptors

1999 • 97 citations

Identification of human chromosome 22 transcribed sequences with ORF expressed sequence tags

2000 • 78 citations

Splicing in the Inner Ear: a Familiar Tune, but What Are the Instruments?

1998 • 77 citations

A Yeast Intronic Splicing Enhancer and Nam8p Are Required for Mer1p-Activated Splicing

2000 • 76 citations

Conserved alternative splicing patterns and splicing signals in the Drosophila sodium channel gene para.

1995 • 65 citations

YIDB: the Yeast Intron DataBase

2000 • 52 citations