On the coupling between DNA replication and mitosis

A major developmental transition in early xenopus embryos: I. characterization and timing of cellular changes at the midblastula stage

1982 • 1,635 citations

Cyclin: A protein specified by maternal mRNA in sea urchin eggs that is destroyed at each cleavage division

1983 • 1,506 citations

Cyclin synthesis drives the early embryonic cell cycle

1989 • 1,223 citations

The RAD9 Gene Controls the Cell Cycle Response to DNA Damage in Saccharomyces cerevisiae

1988 • 1,174 citations

The role of cyclin synthesis and degradation in the control of maturation promoting factor activity

1989 • 1,114 citations

A major developmental transition in early xenopus embryos: II. control of the onset of transcription

1982 • 1,065 citations

Purified maturation-promoting factor contains the product of a Xenopus homolog of the fission yeast cell cycle control gene cdc2+

1988 • 885 citations

The Xenopus cdc2 protein is a component of MPF, a cytoplasmic regulator of mitosis

1988 • 829 citations

Purification of maturation-promoting factor, an intracellular regulator of early mitotic events.

1988 • 640 citations

Cell cycle dynamics of an M-phase-specific cytoplasmic factor in Xenopus laevis oocytes and eggs.

1984 • 575 citations

Nuclear reconstitution in vitro: Stages of assembly around protein-free DNA

1987 • 550 citations

cdc2 is a component of the M phase-specific histone H1 kinase: Evidence for identity with MPF

1988 • 535 citations

Reversible tyrosine phosphorylation of cdc2: Dephosphorylation accompanies activation during entry into mitosis

1989 • 453 citations

Regulation of the cell cycle during early Xenopus development

1984 • 376 citations

Purification of MPF from starfish: Identification as the H1 histone kinase p34cdc2 and a possible mechanism for its periodic activation

1989 • 366 citations

Cell cycle control by the nucleo-cytoplasmic ratio in early Drosophila development

1986 • 338 citations

Caffeine-Induced Uncoupling of Mitosis from the Completion of DNA Replication in Mammalian Cells

1986 • 328 citations

Fission yeast p13 blocks mitotic activation and tyrosine dephosphorylation of the Xenopus cdc2 protein kinase

1989 • 327 citations

The events of the midblastula transition in Xenopus are regulated by changes in the cell cycle

1987 • 312 citations

Dephosphorylation and activation of Xenopusp34cdc2 protein kinase during the cell cycle

1989 • 300 citations

Spontaneous formation of nucleus-like structures around bacteriophage DNA microinjected into Xenopus eggs

1983 • 279 citations

Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene

1988 • 235 citations

Nuclear and cytoplasmic mitotic cycles continue in Drosophila embryos in which DNA synthesis is inhibited with aphidicolin.

1988 • 222 citations

The role of cyclin synthesis, modification and destruction in the control of cell division

1989 • 154 citations

Unraveling of mitotic control mechanisms

1988 • 150 citations

Periodic DNA synthesis in cell-free extracts of Xenopus eggs.

1987 • 127 citations

An investigation of the capacity for cleavage and differentiation in Rana pipiens eggs lacking “functional” chromosomes

1951 • 116 citations

Nuclear activation at the onset of amphibian gastrulation

1966 • 95 citations

Role of nuclear material in the early cell cycle of xenopus embryos

1988 • 61 citations

Exposure to caffeine and suppression of DNA replication combine to stabilize the proteins and RNA required for premature mitotic events

1987 • 40 citations

Control of cell division and cell differentiation by deoxynucleotides in the early embryo of Xenopus laevis

1975 • 36 citations