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Structural and Functional Characteristics of the Class Ib Molecule, Qa-1

Data up to Jan 2025

Published1995
Citations70
References70

Total Citations Per Year

Abstract

References (70)

Recognition of a lipid antigen by CD1-restricted αβ+ T cells

1994 • 976 citations

Stimulation of Human γδ T Cells by Nonpeptidic Mycobacterial Ligands

1994 • 685 citations

A binding site for the T-cell co-receptor CD8 on the α3 domain of HLA-A2

1990 • 527 citations

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

1992 • 522 citations

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

1992 • 502 citations

Why do so many lymphocytes respond to major histocompatibility antigens?

1977 • 462 citations

Cellular peptide composition governed by major histocompatibility complex class I molecules

1990 • 438 citations

The nature of major histocompatibility complex recognition by γδ T cells

1994 • 407 citations

The Role of the Major Histocompatibility Complex in Immunobiology

1981 • 361 citations

Crystal structure at 2.2 Å resolution of the MHC-related neonatal Fc receptor

1994 • 320 citations

Recognition of a Peptide Antigen by Heat Shock--reactive γδ T Lymphocytes

1990 • 291 citations

Ham-2 corrects the class I antigen-processing defect in RMA-S cells

1992 • 289 citations

Identification of a tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen

1994 • 275 citations

Antigen Presentation by Major Histocompatibility Complex Class I-B Molecules

1994 • 248 citations

HLA-E. A novel HLA class I gene expressed in resting T lymphocytes.

1988 • 239 citations

Qa-1 restricted recognition of foreign antigen by a γδ T-cell hybridoma

1989 • 233 citations

Sequence of mouse hepatitis virus A59 mRNA 2: Indications for RNA recombination between coronaviruses and influenza C virus

1988 • 224 citations

Recognition of the product of a novel MHC TL region gene (27b) by a mouse γδ T cell receptor

1990 • 224 citations

On the nature of peptides involved in T cell alloreactivity.

1991 • 220 citations

Endogenously synthesized peptide with an endoplasmic reticulum signal sequence sensitizes antigen processing mutant cells to class I-restricted cell-mediated lysis.

1991 • 215 citations

Murine CD8+ T cells that specifically delete autologous CD4+ T cells expressing Vβ8 TCR: a role of the Qa-1 molecule

1995 • 175 citations

Characteristics of endogenous peptides eluted from the class I MHC molecule HLA-B7 determined by mass spectrometry and computer modeling.

1993 • 164 citations

A new serologically defined locus,Qa-1, in theTla-region of the mouse

1976 • 156 citations

Expression of a membrane protease enhances presentation of endogenous antigens to MHC class I-restricted T lymphocytes

1992 • 155 citations

Immunology '80—Progress in Immunology IV

1982 • 145 citations

Maternally Transmitted Antigen of Mice: A Model Transplantation Antigen

1991 • 141 citations

Comparison of Class I MHC Alleles in Humans and Apes

1990 • 137 citations

A ubiquitous protein is the source of naturally occurring peptides that are recognized by a CD8+ T-cell clone.

1993 • 129 citations

Gamma delta T cells can recognize nonclassical MHC in the absence of conventional antigenic peptides.

1994 • 122 citations

Cytotoxic T lymphocytes recognize a reconstituted class I histocompatibility antigen (HLA-A2) as an allogeneic target molecule.

1990 • 117 citations

Heat shock proteins can regulate expression of the Tla region-encoded class Ib molecule Qa-1.

1991 • 101 citations

Heterogeneity of gene expression of the hemagglutinin-esterase (HE) protein of murine coronaviruses

1991 • 97 citations

Alloreactive cytotoxic T cells recognize MHC class I antigen without peptide specificity.

1991 • 76 citations

A low polymorphic mouse H-2 class I gene from the Tla complex is expressed in a broad variety of cell types.

1987 • 75 citations

Different types of allospecific CTL clones identified by their ability to recognize peptide loading‐defective target cells

1991 • 69 citations

Cell‐type‐specific recognition of allogeneic cells by alloreactive cytotoxic T cells: A consequence of peptide‐dependent allorecognition

1991 • 64 citations

Regulation of Qa-1 expression and determinant modification by an H-2D-linked gene, Qdm

1988 • 59 citations

T cell recognition of QA-1b antigens on cells lacking a functional Tap-2 transporter.

1992 • 57 citations

Biochemical identification of the Qa-1 alloantigen

1980 • 55 citations

Synthesis and processing of molecules bearing thymus leukemia antigen.

1979 • 53 citations

STRESS PROTEINS IN MEDICINE

1996 • 48 citations

Medial Histocompatibility Antigens

1981 • 47 citations

A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site.

1993 • 42 citations

Availability of endogenous peptides limits expression of an M3a-Ld major histocompatibility complex class I chimera.

1994 • 40 citations

The TL region gene 37 encodes a Qa-1 antigen.

1990 • 39 citations

H-2-Nonrestricted Cytotoxic Responses to an Antigen Encoded Telomeric to H-2D

1979 • 36 citations

The peptide p2Ca is immunodominant in allorecognition of Ld by beta chain variable region V beta 8+ but not V beta 8- strains.

1994 • 35 citations

T cell recognition of an HLA-A2-restricted epitope derived from a cleaved signal sequence.

1994 • 35 citations

A cDNA clone encoding the mouse Qa-1a histocompatibility antigen and proposed structure of the putative peptide binding site.

1993 • 35 citations

Structural aspects of allorecognition

1991 • 35 citations

A rat class I cDNA clone with an Alu-like sequence and mapping to two genes in RT1.C/E

1990 • 34 citations

Analysis of T cell receptors specific for recognition of class IB antigens.

1993 • 33 citations

Genetic Variants of Histocompatibility Antigens from Wild Mice

1986 • 28 citations

The Qa-1 alloantigens. II. Evidence for the expression of two Qa-1 molecules by the Qa-1d genotype and for cross-reactivity between Qa-1 and H-2K.

1983 • 28 citations

Expression of mouse Tla region class I genes in tissue enriched for ?? cells

1992 • 27 citations

Expression of differentiation antigens in subpopulations of mouse thymocytes: Regulation at the level of de novo synthesis

1980 • 26 citations

New complexities at the Qa-1 locus

1981 • 23 citations

The class I-b molecule Qa-1 forms heterodimers with H-2Ld and a novel 50-kD glycoprotein encoded centromeric to I-E beta.

1995 • 22 citations

Structure and expression of glycoproteins controlled by the Qa-1 a allele

1981 • 19 citations

Extensive structural homology between H-2 K/D/L antigens and non-polymorphic class I Qa, Tla and “37” molecules suggests they may act as peptide carriers

1989 • 17 citations

A new cell surface molecule closely related to mouse class i transplantation antigens

1989 • 17 citations

Comparative structure of two duplicated T1a class I genes (T10c and 37) of the murine H-2d MHC. Implications on the evolution of the T1a region.

1990 • 16 citations

The differentiation of cytotoxic T cells in vitro. IV. Interleukin-2 production in primary mixed lymphocyte cultures involves cooperation between Qa-1+ and Qa-1- "helper" T cells.

1981 • 15 citations

The Qa-1 alloantigens. I. Identification and molecular weight characterization of glycoproteins controlled by the Qa-1a and Qa-1b alleles.

1981 • 14 citations

Characterization of determinants encoded by four Qa-1 genotypes and their recognition by cloned cytotoxic T lymphocytes.

1983 • 13 citations

Recognition of alternate alleles and mapping of the Qa1 locus.

1981 • 12 citations

The Qa-1 alloantigens. III. Biochemical analysis of the structure and extent of polymorphism of the Qa-1 allelic products.

1985 • 11 citations

Clonal analysis of the anti-Qa-1 cytotoxic T lymphocyte repertoire: definition of the Qa-1d and Qa-1c alloantigens and cross-reactivity with H-2.

1986 • 10 citations

Correlation of Qa-1 determinants defined by antisera and by cytotoxic T lymphocytes

1985 • 9 citations

Polymorphism and expression of Qed.

1983 • 8 citations

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Structural and Functional Characteristics of the Class Ib Molecule, Qa-1 (1995) – Immunological Reviews | Metascience Observatory Explorer