Enhancement of B7‐1 (CD80) expression on B‐lymphoma cells by irradiation

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

1987 • 64,270 citations

Number and evolutionary conservation of α- and β-tubulin and cytoplasmic β- and γ-actin genes using specific cloned cDNA probes

1980 • 1,884 citations

Clonal Expansion Versus Functional Clonal Inactivation: A Costimulatory Signalling Pathway Determines the Outcome of T Cell Antigen Receptor Occupancy

1989 • 1,512 citations

The Role of the CD28 Receptor During T Cell Responses to Antigen

1993 • 1,320 citations

Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK1.5: similarity of L3T4 to the human Leu-3/T4 molecule.

1983 • 1,307 citations

Binding of the B cell activation antigen B7 to CD28 costimulates T cell proliferation and interleukin 2 mRNA accumulation.

1991 • 1,132 citations

A shared alloantigenic determinant on Ia antigens encoded by the I-A and I-E subregions: evidence for I region gene duplication.

1981 • 531 citations

Identification of an Alternative CTLA-4 Ligand Costimulatory for T Cell Activation

1993 • 517 citations

Structure, expression, and T cell costimulatory activity of the murine homologue of the human B lymphocyte activation antigen B7.

1991 • 349 citations

Differential up-regulation of the B7-1 and B7-2 costimulatory molecules after Ig receptor engagement by antigen.

1994 • 293 citations

Signalling through the MHC class II cytoplasmic domain is required for antigen presentation and induces B7 expression

1992 • 285 citations

Inhibition of mixed lymphocyte response by a rat monoclonal antibody to a novel murine lymphocyte activation antigen (MALA-2).

1985 • 229 citations

Expression and function of the murine B7 antigen, the major costimulatory molecule expressed by peritoneal exudate cells.

1992 • 220 citations

Cloned T Lymphocytes and Monoclonal Antibodies as Probes for Cell Surface Molecules Active in T Cell‐Mediated Cytolysis

1982 • 219 citations

Major histocompatibility complex class II+B7-1+ tumor cells are potent vaccines for stimulating tumor rejection in tumor-bearing mice.

1995 • 190 citations

Autocrine effects of fibroblast growth factor in repair of radiation damage in endothelial cells.

1991 • 186 citations

B7-1 is superior to B7-2 costimulation in the induction and maintenance of T cell-mediated antileukemia immunity. Further evidence that B7-1 and B7-2 are functionally distinct.

1996 • 165 citations

Tumor rejection requires a CTLA4 ligand provided by the host or expressed on the tumor: superiority of B7-1 over B7-2 for active tumor immunization.

1996 • 128 citations

Cross-Linking CD21/CD35 or CD19 Increases Both B7-1 and B7-2 Expression on Murine Splenic B Cells

1998 • 96 citations

A cell type-specific enhancer in the human B7.1 gene regulated by NF-kappaB.

1996 • 83 citations

Murine B7 antigen provides a sufficient costimulatory signal for antigen-specific and MHC-restricted T cell activation.

1992 • 83 citations

Tumor Necrosis Factor-α Facilitates Induction of CD80 (B7-1) and CD54 on Human B Cells by Activated T Cells: Complex Regulation by IL-4, IL-10, and CD40L

1995 • 79 citations

Evidence for multiple lytic pathways used by cytotoxic T lymphocytes.

1989 • 74 citations

Rejection of MHC class II-transfected tumor cells requires induction of tumor-encoded B7-1 and/or B7-2 costimulatory molecules.

1996 • 73 citations

Induction of costimulatory molecule B7 in M12 B lymphomas by cAMP or MHC-restricted T cell interaction.

1993 • 65 citations

Inflammatory cytokines IFN-gamma plus TNF-alpha induce regulated expression of CD80 (B7-1) but not CD86 (B7-2) on murine fibroblasts.

1997 • 62 citations

Effect of Irradiation on Cytokine Production, MHC Antigen Expression, and Vaccine Potential of Interleukin-2 and Interferon-γ Gene-Modified Melanoma Cells

1996 • 47 citations

Differential sensitivity of specific and nonspecific antigen-presentation by B cells to a protein synthesis inhibitor.

1990 • 44 citations

Identification of an Alternatively Spliced Form of the Murine Homolog of B7

1994 • 40 citations

Failure of a Second X-ray Dose to Activate Nuclear Factor κB in Normal Rat Astrocytes

1997 • 32 citations

Up‐regulation of human epidermal Langerhans' cell B7‐1 and B7‐2 co‐stimulatory molecules in vivo by solar‐simulating irradiation

1997 • 26 citations

Expression and Functional Analysis of Murine B7 Delineated by a Novel Monoclonal Antibody

1994 • 25 citations

Identification of a promoter element that regulates tissue-specific expression of the human CD80 (B7.1) gene.

1996 • 23 citations

Gamma radiation induces CD69 expression on lymphocytes

1997 • 15 citations

Differential effect of the immunomodulator AS101 on B7-1 and B7-2 costimulatory molecules: role in the antitumoral effects of AS101.

1996 • 15 citations

Enhancement of antigen‐presenting ability of B lymphoma cells by partial inhibition of protein synthesis through inducing B7‐1 expression

1997 • 12 citations

B cells as antigen-presenting cells: Antibody production in vitro against a T-dependent antigen

1986 • 10 citations

Role of Newly Synthesized MHC Class II Molecules in Antigen-Specific Antigen Presentation by B cells

1995 • 7 citations

Identification of an alternatively spliced form of the murine homologue of B7

1994 • 5 citations