Specificity and Cross-Reactivity of Monoclonal Antibodies Reactive with the Core and Lipid A Regions of Bacterial Lipopolysaccharide

Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4

1970 • 253,849 citations

Electrophoretic transfer of proteins from polyacrylamide gels to nitrocellulose sheets: procedure and some applications.

1979 • 54,907 citations

A sensitive silver stain for detecting lipopolysaccharides in polyacrylamide gels

1982 • 3,066 citations

Bacterial lipopolysaccharides : extraction with phenol-water and further applications of the procedure

1965 • 2,566 citations

A New Method for the Extraction of R Lipopolysaccharides

1969 • 1,861 citations

Treatment of Gram-Negative Bacteremia and Shock with Human Antiserum to a MutantEscherichia coli

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Immunochemistry of O and R antigens of Salmonella and related Enterobacteriaceae

1966 • 620 citations

A simple method for polyethylene glycol-promoted hybridization of mouse myeloma cells

1977 • 615 citations

Lipopolysaccharides of Gram-Negative Bacteria

1982 • 460 citations

The Chemistry and Biological Significance of 3-Deoxy-d-manno-2-Octulosonic Acid (KDO)

1981 • 366 citations

Purification and structural determination of nontoxic lipid A obtained from the lipopolysaccharide of Salmonella typhimurium.

1982 • 334 citations

Preparation and Properties of Antisera against the Lipid‐A component of Bacterial Lipopolysaccharides

1971 • 316 citations

Protection against gram-negative bacteremia and endotoxemia with human monoclonal IgM antibodies.

1985 • 316 citations

Structural Studies on the Hexose Region of the Core in Lipopolysaccharides from Enterobacteriaceae

2005 • 265 citations

A Proposed Mechanism for Natural Immunity to Enterobacterial Pathogens

1968 • 188 citations

Passive Immunization against the Local Shwartzman Reaction

1972 • 142 citations

A novel procedure for labeling immunoglobulins by conjugation to oligosaccharide moieties

1984 • 137 citations

Monoclonal antibodies specific for Escherichia coli J5 lipopolysaccharide: cross-reaction with other gram-negative bacterial species

1984 • 126 citations

Immunization with Rough Mutants of Salmonella minnesota. IV. Protection by Antisera to O and Rough Antigens Against Endotoxin

1983 • 112 citations

Enhanced survival in Pseudomonas aeruginosa septicemia associated with high levels of circulating antibody to Escherichia coli endotoxin core.

1983 • 104 citations

α‐2→4‐Interlinked 3‐deoxy‐<scp>d</scp>‐manno‐octulosonic acid disaccharide

1984 • 102 citations

Immunochemical Studies on Core Lipopolysaccharides of Enterobacteriaceae of Different Genera

1970 • 95 citations

The immunogenicity and antigenicity of lipid A are influenced by its physicochemical state and environment

1987 • 94 citations

Total synthesis of lipid A, active principle of bacterial endotoxin.

1984 • 87 citations

Immunogenic Properties of Lipid A

1984 • 85 citations

Concepts of the Chemical Structure of Lipid A

1984 • 81 citations

Human monoclonal antibodies that recognize conserved epitopes in the core-lipid A region of lipopolysaccharides.

1987 • 79 citations

Immunization with R mutants of Salmonella minnesota. II. Serological response to lipid A and the lipopolysaccharide of Re mutants

1977 • 77 citations

Structure and biosynthesis of O-antigens.

1984 • 76 citations

Use of synthetic antigens to determine the epitope specificities of monoclonal antibodies against the 3-deoxy-D-manno-octulosonate region of bacterial lipopolysaccharide

1987 • 71 citations

Mouse monoclonal antibodies reactive with J5 lipopolysaccharide exhibit extensive serological cross-reactivity with a variety of gram-negative bacteria

1984 • 68 citations

Failure of Monoclonal Antibodies to Core Glycolipid to Bind Intact Smooth Strains of Escherichia coli

1985 • 67 citations

Monoclonal antibodies to enterobacterial common antigen and to Escherichia coli lipopolysaccharide outer core: demonstration of an antigenic determinant shared by enterobacterial common antigen and E. coli K5 capsular polysaccharide

1985 • 66 citations

Isolation and characterization of murine monoclonal antibodies specific for gram-negative bacterial lipopolysaccharide: association of cross-genus reactivity with lipid A specificity

1987 • 66 citations

Microbial Polysaccharides**This article is dedicated to Professor Michael Heidelberger, New York, the great pioneer of polysaccharide immunochemistry.

1975 • 64 citations

Characterization of murine monoclonal antibodies to Escherichia coli J5

1986 • 64 citations

Immunogenicity and antigenicity of synthetic Escherichia coli lipid A

1986 • 40 citations

Structural investigations on the inner core region of lipopolysaccharides fromSalmonella minnesota rough mutants

1985 • 39 citations

Immunology and Immunochemistry of Synthetic and Semisynthetic Salmonella O-Antigen-Specific Glycoconjugates

1983 • 32 citations

The Biosynthesis of Cell Wall Lipopolysaccharide in Escherichia coli

1973 • 29 citations

Antibodies to Lipid A: Occurrence in Humans

1984 • 26 citations

Monoclonal antibodies detecting novel structures in the core region ofSalmonella minnesotalipopolysaccharide

1987 • 25 citations

In vitro antigenic reactivity of synthetic lipid a analogues as determined by monoclonal and conventional antibodies

1985 • 24 citations

Immunoprotective murine monoclonal antibodies specific for the outer-core polysaccharide and for the O-antigen of Escherichia coli 0111:B4 lipopolysaccharide (LPS).

1987 • 23 citations

Binding activity of a murine anti-lipid A monoclonal antibody

1985 • 20 citations

Production and characterization of KDO-specific monoclonal antibodies recognizing lipopolysaccharides from heptoseless mutants ofSalmonella

1985 • 19 citations

Inhibition of lipopolysaccharide mitogenicity with characterized anti-lipid A monoclonal antibodies.

1985 • 14 citations

Antibodies to endotoxin core determinants in normal subjects and in immune globulins for intravenous use

1987 • 12 citations

Monoclonal antibodies that recognize epitopes in the core and lipid A region of lipopolysaccharides.

1988 • 4 citations