Monoclonal Antibody-Mediated Inhibition of RNA Binding and Annealing Activities of HIV Type 1 Nucleocapsid Protein

Nucleotide sequence of the AIDS virus, LAV

1985 • 1,225 citations

Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1.

1989 • 831 citations

A novel hydrogel matrix on gold surfaces in surface plasmon resonance sensors for fast and efficient covalent immobilization of ligands

1990 • 759 citations

Mutations of RNA and protein sequences involved in human immunodeficiency virus type 1 packaging result in production of noninfectious virus

1990 • 531 citations

Biospecific interaction analysis using biosensor technology

1993 • 522 citations

Retroviruses

1988 • 512 citations

Noninfectious human immunodeficiency virus type 1 mutants deficient in genomic RNA

1990 • 380 citations

Cis elements and Trans-acting factors involved in the RNA dimerization of the human immunodeficiency virus HIV-1

1990 • 321 citations

Point mutants of Moloney murine leukemia virus that fail to package viral RNA: evidence for specific RNA recognition by a "zinc finger-like" protein sequence.

1988 • 312 citations

HIV-1 reverse transcriptase specifically interacts with the anticodon domain of its cognate primer tRNA.

1989 • 301 citations

Viral RNA annealing activities of human immunodeficiency virus type 1 nucleocapsid protein require only peptide domains outside the zinc fingers.

1992 • 282 citations

Small finger protein of avian and murine retroviruses has nucleic acid annealing activity and positions the replication primer tRNA onto genomic RNA.

1988 • 255 citations

Construction and analysis of deletion mutations in the pol gene of moloney murine leukemia virus: A new viral function required for productive infection

1984 • 244 citations

Determination of the structure of the nucleocapsid protein NCp7 from the human immunodeficiency virus type 1 by 1H NMR.

1992 • 243 citations

Detection of antigen—antibody interactions by surface plasmon resonance. Application to Epitope Mapping

1990 • 225 citations

Biochemical and immunological analysis of human immunodeficiency virus gag gene products p17 and p24

1988 • 203 citations

Rous sarcoma virus nucleic acid-binding protein p12 is necessary for viral 70S RNA dimer formation and packaging

1986 • 187 citations

Site on the RNA of an avian sarcoma virus at which primer is bound

1975 • 170 citations

Evolution of the V3 envelope domain in proviral sequences and isolates of human immunodeficiency virus type 1 during transition of the viral biological phenotype

1992 • 169 citations

Transactivation of the minus-strand DNA transfer by nucleocapsid protein during reverse transcription of the retroviral genome.

1994 • 168 citations

A study of the dimer formation of Rous sarcoma virus RNA and of its effect on viral protein synthesisin vitro

1990 • 166 citations

Secondary structural features in the 70S RNAs of Moloney murine leukemia and Rous sarcoma viruses as observed by electron microscopy

1981 • 148 citations

High-molecular-weight RNAs of AKR, NZB, and wild mouse viruses and avian reticuloendotheliosis virus all have similar dimer structures

1978 • 142 citations

First large scale chemical synthesis of the 72 amino acid HIV-1 nucleocapsid protein NCp7 in an active form

1991 • 139 citations

Identification of a binding site for the human immunodeficiency virus type 1 nucleocapsid protein.

1993 • 135 citations

RD-114, baboon, and woolly monkey viral RNAs compared in size and structure

1976 • 133 citations

Immunological and Chemical Analysis of P6, the Carboxyl-Terminal Fragment of HIV P15

1987 • 104 citations

Isolation of a Ribonucleoprotein Structure from Oncornaviruses

1973 • 101 citations

Deletions in the tRNA(Lys) primer-binding site of human immunodeficiency virus type 1 identify essential regions for reverse transcription

1991 • 100 citations

Rat Hybridomas and Rat Monoclonal Antibodies (1990)

2017 • 98 citations

C-Terminal retroviral-type zinc finger domain from the HIV-1 nucleocapsid protein is structurally similar to the N-terminal zinc finger domain

1991 • 95 citations

Avian retroviral RNA encapsidation: reexamination of functional 5' RNA sequences and the role of nucleocapsid Cys-His motifs

1993 • 94 citations

Basic amino acids flanking the zinc finger of Moloney murine leukemia virus nucleocapsid protein NCp10 are critical for virus infectivity

1993 • 93 citations

Interaction of HIV-1 reverse transcriptase with a synthetic form of its replication primer, tRNA^Lys,3

1991 • 91 citations

It is Rous Sarcoma virus protein P12 and not P19 that binds tightly to Rous Sarcoma virus RNA

1984 • 80 citations

Specificity of Rous sarcoma virus nucleocapsid protein in genomic RNA packaging

1992 • 74 citations

Specificity of photochemical crosslinking in protein-nucleic acid complexes: identification of the interacting residues in RNase-pyrimidine nucleotide complex

1977 • 65 citations

Physicochemical properties of cloned nucleocapsid protein from HIV. Interactions with metal ions

1991 • 60 citations

Solid phase synthesis of the retro viral nucleocapsid protein NCp10 of Moloney Murine Leukaemia virus and related “zinc‐fingers” in free SH forms

1990 • 58 citations

A comparison of spleen and lymph node cells as fusion partners for the raising of monoclonal antibodies after different routes of immunisation

1987 • 48 citations

Complete amino acid sequence of the basic nucleic acid binding protein of feline leukemia virus

1984 • 43 citations

Domain structure of the human immunodeficiency virus reverse transcriptase.

1992 • 22 citations