(—)-Δ9-Tetrahydrocannabinol Antagonizes the Peripheral Cannabinoid Receptor-mediated Inhibition of Adenylyl Cyclase

Molecular characterization of a peripheral receptor for cannabinoids

1993 • 4,950 citations

Structure of a cannabinoid receptor and functional expression of the cloned cDNA

1990 • 4,933 citations

SR141716A, a potent and selective antagonist of the brain cannabinoid receptor

1994 • 1,743 citations

Comparison of the pharmacology and signal transduction of the human cannabinoid CB1 and CB2 receptors.

1995 • 838 citations

Cannabinoids inhibit N-type calcium channels in neuroblastoma-glioma cells.

1992 • 694 citations

Molecular cloning of a human cannabinoid receptor which is also expressed in testis

1991 • 679 citations

Mast cells express a peripheral cannabinoid receptor with differential sensitivity to anandamide and palmitoylethanolamide.

1995 • 625 citations

In vitro mutagenesis and the search for structure-function relationships among G protein-coupled receptors

1992 • 470 citations

Cannabinoid structure-activity relationships: correlation of receptor binding and in vivo activities.

1993 • 440 citations

Anandamide, an endogenous cannabinoid, inhibits calcium currents as a partial agonist in N18 neuroblastoma cells

1993 • 356 citations

Cannabinoid inhibition of adenylate cyclase. Pharmacology of the response in neuroblastoma cell membranes.

1984 • 353 citations

Anandamide, a Brain Endogenous Compound, Interacts Specifically with Cannabinoid Receptors and Inhibits Adenylate Cyclase

1993 • 297 citations

Localization of cannabinoid receptors and nonsaturable high-density cannabinoid binding sites in peripheral tissues of the rat: implications for receptor-mediated immune modulation by cannabinoids.

1994 • 270 citations

Identification of a functionally relevant cannabinoid receptor on mouse spleen cells that is involved in cannabinoid-mediated immune modulation.

1992 • 243 citations

Nonclassical cannabinoid analgetics inhibit adenylate cyclase: development of a cannabinoid receptor model.

1988 • 243 citations

Cannabinoid Receptors and Modulation of Cyclic AMP Accumulation in the Rat Brain

1990 • 209 citations

The peripheral cannabinoid receptor: adenylate cyclase inhibition and G protein coupling

1995 • 208 citations

A novel probe for the cannabinoid receptor

1992 • 201 citations

Activation of the human peripheral cannabinoid receptor results in inhibition of adenylyl cyclase

1995 • 186 citations

Cannabinoids enhance human B‐cell growth at low nanomolar concentrations

1995 • 168 citations

Effects of putative cannabinoid receptor ligands, anandamide and 2-arachidonyl-glycerol, on immune function in B6C3F1 mouse splenocytes.

1995 • 134 citations

Suppression of the humoral immune response by cannabinoids is partially mediated through inhibition of adenylate cyclase by a pertussis toxin-sensitive G-protein coupled mechanism

1994 • 131 citations

[2] Cellular responsiveness to hormones and neutrotransmitters: Conversion of [3H]Adenine to [3H]cAMP in cell monolayers, cell suspensions, and tissue slices

1991 • 124 citations

Synthesis of the individual, pharmacologically distinct, enantiomers of a tetrahydrocannabinol derivative

1990 • 114 citations

Syntheses of .DELTA.1-tetrahydrocannabinol and related cannabinoids

1972 • 101 citations

[41] Methods for introducing DNA into mammalian cells

1990 • 98 citations

Tetrahydrocannabinol-Induced Suppression of Macrophage Spreading and Phagocytic Activity In Vitro

1986 • 83 citations

Low doses of anandamides inhibit pharmacological effects of delta 9-tetrahydrocannabinol.

1995 • 74 citations

Regulation of adenylate cyclase by chronic exposure to cannabimimetic drugs.

1988 • 73 citations

Receptors: A Quantitative Approach

1984 • 64 citations

Molecular cloning and expression of a novel type V adenylyl cyclase from rabbit myocardium

1994 • 50 citations

Differential coupling of m1, m2 and m3 muscarinic receptor subtypes to inositol 1,4,5-trisphosphate and adenosine 3',5'-cyclic monophosphate accumulation in Chinese hamster ovary cells.

1995 • 49 citations