Direct effects of 13-cis and all-trans retinoic acid on normal bone marrow (BM) progenitors: Comparative study on BM mononuclear cells and on isolated CD 34+ BM cells

Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia

1988 • 2,380 citations

Chromosomal translocation t(15;17) in human acute promyelocytic leukemia fuses RARα with a novel putative transcription factor, PML

1991 • 1,463 citations

The PML-RARα fusion mRNA generated by the t(15;17) translocation in acute promyelocytic leukemia encodes a functionally altered RAR

1991 • 1,371 citations

The t(15;17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor α gene to a novel transcribed locus

1990 • 1,349 citations

Differentiation Therapy of Acute Promyelocytic Leukemia with Tretinoin (All-trans-Retinoic Acid)

1991 • 1,298 citations

All-trans retinoic acid as a differentiation therapy for acute promyelocytic leukemia. I. Clinical results [see comments]

1990 • 1,224 citations

Molecular Analysis of Acute Promyelocytic Leukemia Breakpoint Cluster Region on Chromosome 17

1990 • 650 citations

Terminal differentiation of human promyelocytic leukemic cells in primary culture in response to retinoic acid

1981 • 566 citations

A clinical and experimental study on all-trans retinoic acid-treated acute promyelocytic leukemia patients

1991 • 412 citations

All-trans retinoic acid in acute promyelocytic leukemias. II. In vitro studies: structure-function relationship

1990 • 390 citations

Translocation breakpoint of acute promyelocytic leukemia lies within the retinoic acid receptor alpha locus.

1991 • 253 citations

Retinoic acid. Inhibition of the clonal growth of human myeloid leukemia cells.

1982 • 224 citations

Retinoic acid enhances colony-stimulating factor-induced clonal growth of normal human myeloid progenitor cells in vitro*1

1982 • 178 citations

The product of the proto-oncogene c-kit (P145c-kit) is a human bone marrow surface antigen of hemopoietic precursor cells which is expressed on a subset of acute non-lymphoblastic leukemic cells.

1991 • 98 citations

The retinoic acid receptor alpha gene is rearranged in retinoic acid-sensitive promyelocytic leukemias.

1990 • 97 citations

Novel Retinoic Acid Receptor- Transcripts in Acute Promyelocytic Leukemia Responsive to All-trans-Retinoic Acid

1990 • 80 citations

All-trans retinoic acid modulates the retinoic acid receptor-alpha in promyelocytic cells.

1991 • 77 citations

Retinoids. Structure-function relationship in normal and leukemic hematopoiesis in vitro.

1986 • 69 citations

Effect of 1,25 dihydroxyvitamin D3 and retinoic acid on normal human pluripotent (CFU-mix), erythroid (BFU-E), and myeloid (CFU-C) progenitor cell growth and differentiation patterns.

1986 • 55 citations

Rearrangement of the retinoic acid receptor gene in acute promyelocytic leukemia.

1991 • 49 citations

cis-Retinoic acid stimulates the clonal growth of some myeloid leukemia cells in vitro

1987 • 45 citations

Treatment of promyelocytic blast crisis of chronic myelogenous leukemia with all trans-retinoic acid.

1991 • 43 citations

1-B-D arabinofuranosyl cytosine and all-trans retinoic acid in combination accelerates and increases monocyte differentiation of myeloid leukemic cells

1986 • 37 citations

All‐trans‐retinoic acid treatment and retinoic acid receptor alpha gene rearrangement in acute promyelocytic leukemia: A model for differentiation therapy

1992 • 30 citations

Retinoic acid induced HL-60 myeloid differentiation: Dependence of early and late events on isomeric structure

1986 • 29 citations

The effect of retinoids on CFU‐GM from normal subjects and patients with myelodysplastic syndrome

1985 • 26 citations

Inhibition of differentiation and proliferation of colony-stimulating factor-induced clonal growth of normal human marrow cells in vitro by retinoic acid.

1983 • 19 citations

Interactions between retinoic acid and colony-stimulating factors affecting the blast cells of acute myeloblastic leukemia.

1991 • 19 citations

Effects of retinoic acid, 1,25-dihydroxyvitamin D3, cytosine arabinoside and α-interferon on bone marrow cells from patients with myelodysplastic syndromes

1989 • 13 citations

Roles for the heliodynamic hormones, all trans retinoic acid and 1α,25-dihydroxyvitamin D3, in control of the hematopoietic cell cycle

1991 • 10 citations