Increasing value and reducing waste in biomedical research regulation and management
Data up to Jan 2025
Total Citations Per Year
Abstract
References (94)
The Principles of Humane Experimental Technique
1960 • 4,666 citations
Avoidable waste in the production and reporting of research evidence
2009 • 1,916 citations
Ethics and Clinical Research
1966 • 1,851 citations
Practical Clinical Trials
2003 • 1,686 citations
Industry sponsorship and research outcome
2017 • 1,431 citations
Methods to increase response to postal and electronic questionnaires
2009 • 1,293 citations
Barriers to recruiting underrepresented populations to cancer clinical trials: A systematic review
2007 • 953 citations
What influences recruitment to randomised controlled trials? A review of trials funded by two UK funding agencies
2006 • 833 citations
Industry sponsorship and research outcome
2012 • 582 citations
Avoidable Waste in the Production and Reporting of Research Evidence
2009 • 576 citations
Recruitment to randomised trials: strategies for trial enrolment and participation study. The STEPS study
2007 • 415 citations
Factors that limit the quality, number and progress of randomised controlled trials.
1999 • 373 citations
Strategies to improve recruitment to randomised controlled trials
2010 • 369 citations
A reinvestigation of recruitment to randomised, controlled, multicenter trials: a review of trials funded by two UK funding agencies
2013 • 338 citations
Increasing recruitment to randomised trials: a review of randomised controlled trials
2006 • 315 citations
Improving the recruitment activity of clinicians in randomised controlled trials: a systematic review
2012 • 303 citations
Progress in Childhood Cancer: 50 Years of Research Collaboration, a Report From the Children's Oncology Group
2008 • 268 citations
The Nuremberg Code and the Nuremberg Trial
1996 • 257 citations
Recruiting patients to medical research: double blind randomised trial of “opt-in” versus “opt-out” strategies
2005 • 248 citations
Impact of patient involvement in mental health research: longitudinal study
2013 • 241 citations
Written informed consent and selection bias in observational studies using medical records: systematic review
2009 • 235 citations
Are research ethics committees behaving unethically? Some suggestions for improving performance and accountability
1996 • 187 citations
THE ANIMALS (SCIENTIFIC PROCEDURES) ACT 1986
1986 • 181 citations
Outcomes of patients who participate in randomized controlled trials compared to similar patients receiving similar interventions who do not participate
2008 • 174 citations
Better Outcomes for Patients Treated at Hospitals That Participate in Clinical Trials
2008 • 168 citations
Pragmatic randomised trials using routine electronic health records: putting them to the test
2012 • 167 citations
Specific barriers to the conduct of randomized trials
2008 • 163 citations
Invisible Barriers to Clinical Trials: The Impact of Structural, Infrastructural, and Procedural Barriers to Opening Oncology Clinical Trials
2006 • 161 citations
Ensuring trial validity by data quality assurance and diversification of monitoring methods
2008 • 151 citations
Testing Treatments: Better Research for Better Healthcare
2006 • 149 citations
Informed consent for clinical trials: in search of the “best” method
1998 • 141 citations
Assessing the Impact of Protocol Design Changes on Clinical Trial Performance
2008 • 139 citations
The Routledge companion to ethics
2011 • 137 citations
Randomized Clinical Trials — Removing Unnecessary Obstacles
2013 • 121 citations
Incentives and disincentives to participation by clinicians in randomised controlled trials
2007 • 118 citations
Testing Treatments: Better Research for Better Healthcare
2006 • 110 citations
Patient Outcomes with Teaching Versus Nonteaching Healthcare: A Systematic Review
2006 • 108 citations
National survey of British public's views on use of identifiable medical data by the National Cancer Registry
2006 • 100 citations
The 50th Anniversary of the Declaration of Helsinki
2013 • 97 citations
A statistical approach to central monitoring of data quality in clinical trials
2012 • 97 citations
Clinical trials bureaucracy: unintended consequences of well-intentioned policy
2006 • 87 citations
Attitudes towards biomedical use of tissue sample collections, consent, and biobanks among Finns
2009 • 86 citations
Rates of inclusion of teenagers and young adults in England into National Cancer Research Network clinical trials: Report from the National Cancer Research Institute (NCRI) Teenage and Young Adult Clinical Studies Development Group
2008 • 84 citations
Effects on patients of their healthcare practitioner's or institution's participation in clinical trials: a systematic review
2011 • 82 citations
Patterns of care and survival for children with acute lymphoblastic leukaemia diagnosed between 1980 and 1994
1999 • 82 citations
The potential for central monitoring techniques to replace on-site monitoring: findings from an international multi-centre clinical trial
2011 • 81 citations
Conventional consent with opting in versus simplified consent with opting out: An exploratory trial for studies that do not increase patient risk
1998 • 73 citations
The Value of Source Data Verification in a Cancer Clinical Trial
2012 • 72 citations
Population survival from childhood cancer in Britain during 1978–2005 by eras of entry to clinical trials
2012 • 66 citations
The Unintended Consequences of Clinical Trials Regulations
2009 • 65 citations
Toward protecting the safety of participants in clinical trials
2003 • 61 citations
Research ethics committees in Europe: implementing the directive, respecting diversity
2006 • 49 citations
Biobank research: who benefits from individual consent?
2011 • 48 citations
Towards sustainable clinical trials
2007 • 46 citations
Meeting the challenges facing research ethics committees: some practical suggestions
1998 • 45 citations
Viewpoint: A method to estimate the cost in lives of ethics board review of biomedical research
2011 • 44 citations
A systematic review of on-site monitoring methods for health-care randomised controlled trials
2013 • 43 citations
Funding for practice-oriented clinical research
2006 • 43 citations
Impediments to Clinical Research in the United States
2012 • 42 citations
Over-regulation of clinical research: a threat to public health
2005 • 41 citations
Informed consent for record linkage: a systematic review
2012 • 41 citations
Regulation of Therapeutic Research is Compromising the Interests of Patients1
2007 • 39 citations
Validation of a risk-assessment scale and a risk-adapted monitoring plan for academic clinical research studies — The Pre-Optimon study
2010 • 38 citations
The successful integration of research and care: How pediatric oncology became the subspecialty in which research defines the standard of care
2011 • 38 citations
Iatrogenic hazards and their effects.
1975 • 38 citations
Adverse effects of a multicentre system for ethics approval on the progress of a prospective multicentre trial of cancer treatment: how many patients die waiting?
2007 • 37 citations
Need for a wider view of autonomy in epidemiological research
2010 • 34 citations
Research governance: ethical issues
2006 • 33 citations
Bridging the gap: improving clinical development and the regulatory pathways for health products for neglected diseases
2010 • 32 citations
Research governance: where did it come from, what does it mean?
2005 • 32 citations
Research Governance: Where did it Come From, What Does it Mean?
2005 • 31 citations
Regulatory impediments jeopardizing the conduct of clinical trials in Europe funded by the National Institutes of Health
2010 • 31 citations
Does the European Clinical Trials Directive really improve clinical trial approval time?
2008 • 28 citations
Informed consent in medical research
2001 • 26 citations
Research ethics committees in the UK--the pressure is now on research and development departments
2005 • 26 citations
Testing Treatments: Better Research for Better Healthcare (2nd edn)
2013 • 23 citations
Research Governance: Regulating Risk and Reducing Harm?
2006 • 23 citations
Research governance: regulating risk and reducing harm?
2005 • 23 citations
A Proposal To Protect Privacy Of Health Information While Accelerating Comparative Effectiveness Research
2010 • 22 citations
Data sharing among data monitoring committees and responsibilities to patients and science
2013 • 20 citations
Streamlined research governance: are we there yet?
2010 • 20 citations
Building a Protocol Expressway: The Case of Mayo Clinic Cancer Center
2009 • 19 citations
Regulatory challenges: Lessons from recent West Nile virus trials in the United States
2006 • 19 citations
Eligibility for Randomized Trials of Treatments Specifically for Intracerebral Hemorrhage
2013 • 18 citations
Research Governance: Ethical Issues
2006 • 18 citations
Deficiencies in proposed new EU regulation of clinical trials
2012 • 18 citations
Ethics of Research
2009 • 18 citations
A systematic search for reports of site monitoring technique comparisons in clinical trials
2012 • 17 citations
Research Ethics Committees in the UK—the Pressure is Now on Research and Development Departments
2005 • 15 citations
Addressing uncertainties about the effects of treatments offered to NHS patients: whose responsibility?
2007 • 15 citations
Impact of the European Clinical Trials Directive on prospective academic clinical trials associated with BMT
2010 • 13 citations
Publishing information about ongoing clinical trials for patients
2010 • 9 citations
A new NHS research strategy
2006 • 8 citations
The clinical problems of dosage and the route of administration of antilymphocyte globulin.
1976 • 7 citations
Cited By (0)
No citing papers found in database