Role of Insulin-Like Growth Factor Binding Protein-2 and Its Limited Proteolysis in Neuroblastoma Cell Proliferation: Modulation by Transforming Growth Factor-β and Retinoic Acid*

Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays

1983 • 52,849 citations

Insulin-Like Growth Factors and Their Binding Proteins: Biological Actions*

1995 • 4,419 citations

Plasminogen Activators, Tissue Degradation, and Cancer

1985 • 2,584 citations

Morphology and growth, tumorigenicity, and cytogenetics of human neuroblastoma cells in continuous culture.

1973 • 1,284 citations

Analysis of serum insulin-like growth factor binding proteins using Western blotting: Use of the method for titration of the binding proteins and competitive binding studies

1986 • 1,158 citations

Evidence that transforming growth factor-β is a hormonally regulated negative growth factor in human breast cancer cells

1987 • 998 citations

Induction of the growth inhibitor IGF-binding protein 3 by p53

1995 • 884 citations

Cell-Associated Plasminogen Activation: Regulation and Physiological Functions

1988 • 826 citations

Decreased expression of N-myc precedes retinoic acid-induced morphological differentiation of human neuroblastoma

1985 • 644 citations

Coordinate Morphological and Biochemical Interconversion of Human Neuroblastoma Cells<xref ref-type="fn" rid="FN2">2</xref>

1983 • 544 citations

Insulin-like growth factor (IGF)-independent action of IGF-binding protein-3 in Hs578T human breast cancer cells. Cell surface binding and growth inhibition

1993 • 481 citations

Human osteoblast-derived insulin-like growth factor (IGF) binding protein-5 stimulates osteoblast mitogenesis and potentiates IGF action.

1992 • 351 citations

Growth factors in the regulation of pericellular proteolysis: a review.

1989 • 342 citations

Transforming growth factor-beta is a strong and fast acting positive regulator of the level of type-1 plasminogen activator inhibitor mRNA in WI-38 human lung fibroblasts.

1987 • 247 citations

The developing CNS: a scenario for the action of proinsulin, insulin and insulin-like growth factors

1995 • 243 citations

Cloning, sequence analysis and expression of a cDNA encoding a novel insulin-like growth factor binding protein (IGFBP-2).

1989 • 240 citations

Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II.

1989 • 188 citations

Autocrine regulation of cell proliferation by the insulin-like growth factor (IGF) and IGF binding protein-3 protease system in a human prostate carcinoma cell line (PC-3).

1995 • 164 citations

Transfection of the human insulin-like growth factor binding protein-3 gene into Balb/c fibroblasts inhibits cellular growth.

1993 • 160 citations

Production of plasminogen activator by migrating cephalic neural crest cells.

1985 • 149 citations

Characterization of Induction of Protooncogene c-myc and Cellular Growth in Human Vascular Smooth Muscle Cells by Insulin and IGF-I

1989 • 135 citations

Insulin-like growth factor II-mediated proliferation of human neuroblastoma.

1991 • 135 citations

Isolation from human cerebrospinal fluid of a new insulin‐like growth factor‐binding protein with a selective affinity for IGF‐II

1989 • 116 citations

Characterization of Insulin-Like Growth Factor Binding Proteins Produced in the Rat Central Nervous System*

1990 • 115 citations

Interactions between insulin-like growth factor-I (IGF-I) and the system of plasminogen activators and their inhibitors in the control of IGF-binding protein-3 production and proteolysis in human osteosarcoma cells.

1994 • 84 citations

Preferential Measurement of Insulin-Like Growth Factor (IGF) I-Related Peptides in Serum with the Aid of IGF-Binding Proteins (IGF BPs) Produced by Rat Liver in Culture. Estimation of Serum IGF BP Levels*

1984 • 78 citations

Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors

1991 • 69 citations

Episomal expression of sense and antisense insulin-like growth factor (IGF)-binding protein-4 complementary DNA alters the mitogenic response of a human colon cancer cell line (HT-29) by mechanisms that are independent of and dependent upon IGF-I.

1994 • 67 citations

Porcine Aortic Smooth Muscle Cells Secrete a Serine Protease for Insulin-like Growth Factor Binding Protein-2

1995 • 67 citations

The Insulin-like growth factors : structure and biological functions

1992 • 60 citations

Induction of morphological differentiation of human neuroblastoma cells is accompanied by induction of tissue‐type plasminogen activator

1989 • 59 citations

Retinoic Acid Induction of Human Tissue-type Plasminogen Activator Gene Expression via a Direct Repeat Element (DR5) Located at −7 Kilobases

1995 • 57 citations

Transfection of the human insulin-like growth factor binding protein-3 gene into Balb/c fibroblasts inhibits cellular growth

1993 • 53 citations

An IGF binding protein is an inhibitor of fgf stimulation

1991 • 47 citations

Insulin-like growth factor I regulates c-myc and GAP-43 messenger ribonucleic acid expression in SH-SY5Y human neuroblastoma cells.

1993 • 47 citations

Modulation by retinoic acid of insulin-like growth factor (IGF) and IGF binding protein expression in human SK-N-SH neuroblastoma cells

1996 • 39 citations

Effects of serum and insulin-like growth factors on human neuroblastoma cell growth

1993 • 36 citations

Intrinsic Bioactivity of Insulin-Like Growth Factor-Binding Proteins from Vascular Endothelial Cells*

1990 • 34 citations

Expression of insulin-like growth factor binding protein-1 and -2 genes through the perinatal period in the rat.

1993 • 29 citations

Expression and Down‐Regulation by Retinoic Acid of IGF Binding Protein‐2 and ‐4 in Medium from Human Neuroblastoma Cells

1994 • 28 citations

Synthesis and secretion of insulin-like growth factor (IGF)-II and IGF binding protein-2 by cultivated brain meningeal cells

1995 • 28 citations

The Insulin-Like Growth Factors. Structure and Biological Functions

1993 • 19 citations

Differential regulation by TGF-beta 1 and insulin of insulin-like growth factor binding protein-2 in IEC-6 cells

1995 • 18 citations

Second Messengers Mediating Gene Expression Essential to Neurite Formation Directed by Insulin and Insulin-Like Growth Factors

1991 • 16 citations