Mapping proteinDNA interactions in vivo with formaldehyde: Evidence that histone H4 is retained on a highly transcribed gene

Molecular Cloning: A Laboratory Manual

2001 • 133,517 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1983 • 26,063 citations

Genomic sequencing.

1984 • 8,343 citations

A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity

1984 • 4,899 citations

THE HEAT-SHOCK RESPONSE

1986 • 4,580 citations

The induction of gene activity in drosophila by heat shock

1979 • 1,308 citations

The 5′ ends of Drosophila heat shock genes in chromatin are hypersensitive to DNase I

1980 • 1,114 citations

Nucleosome Structure

1980 • 923 citations

The Heat Shock Respons

1985 • 809 citations

A protein binds to a satellite DNA repeat at three specific sites that would be brought into mutual proximity by DNA folding in the nucleosome

1984 • 674 citations

Nucleosomes inhibit the initiation of transcription but allow chain elongation with the displacement of histones

1987 • 609 citations

Assembly and propagation of repressed and derepressed chromosomal states

1985 • 518 citations

Two protein-binding sites in chromatin implicated in the activation of heat-shock genes

1984 • 474 citations

Formaldehyde-mediated DNA-protein crosslinking: a probe for in vivo chromatin structures.

1985 • 440 citations

Chromatin

1982 • 399 citations

The chromatin structure of specific genes: II. Disruption of chromatin structure during gene activity

1979 • 389 citations

Selective arrangement of ubiquitinated and D1 protein-containing nucleosomes within the drosophila genome

1982 • 362 citations

RNA polymerase II interacts with the promoter region of the noninduced hsp70 gene in Drosophila melanogaster cells.

1986 • 355 citations

A mammalian high mobility group protein recognizes any stretch of six A.T base pairs in duplex DNA.

1986 • 313 citations

Separation and partial characterization of three functional steps in transcription initiation by human RNA polymerase II.

1985 • 311 citations

Studies on Chromatin

1964 • 289 citations

Sequence of three copies of the gene for the major Drosophila heat shock induced protein and their flanking regions

1980 • 286 citations

A stretch of “late” SV40 viral DNA about 400 bp long which includes the origin of replication is specifically exposed in SV40 minichromosomes

1979 • 278 citations

Detecting protein-DNA interactions in vivo: distribution of RNA polymerase on specific bacterial genes.

1984 • 250 citations

Studies on histone organization in the nucleosome using formaldehyde as a reversible cross-linking agent

1978 • 236 citations

Reversible changes in nucleosome structure and histone H3 accessibility in transcriptionally active and inactive states of rDNA chromatin

1983 • 231 citations

In vivo interactions of RNA polymerase II with genes of Drosophila melanogaster.

1985 • 229 citations

Structural analysis of a triple complex between the histone octamer, a Xenopus gene for 5S RNA and transcription factor IIIA.

1985 • 222 citations

Properties of formaldehyde-treated nucleohistone

1969 • 196 citations

Sequence organization and transcription at two heat shock loci in Drosophila.

1978 • 174 citations

A bacteriophage RNA polymerase transcribes through a Xenopus 5S RNA gene transcription complex without disrupting it

1986 • 169 citations

Changes of nucleosome frequency in nucleolar and non-nucleolar chromatin as a function of transcription: an electron microscopic study

1978 • 161 citations

Core Particle, Fiber, and Transcriptionally Active Chromatin Structure

1986 • 159 citations

Electron Microscopic Analysis of Chromosome Metabolism in the Drosophila melanogaster Embryo

1978 • 154 citations

A bacteriophage RNA polymerase transcribes in vitro through a nucleosome core without displacing it

1987 • 148 citations

Chromatin structure of hsp 70 genes, activated by heat shock: Selective removal of histones from the coding region and their absence from the 5′ region

1984 • 136 citations

Rapid and reversible changes in nucleosome structure accompany the activation, repression, and superinduction of murine fibroblast protooncogenes c-fos and c-myc.

1987 • 125 citations

Nucleosomes are phased along the mouse β-major globin gene in erythroid and nonerythroid cells

1986 • 119 citations

Chromatin fine structure of active and repressed genes

1981 • 114 citations

Sarkosyl activation of RNA polymerase activity in mitotic mouse cells

1974 • 108 citations

Structure of the active nucleolar chromatin of Xenopus laevis oocytes

1982 • 89 citations

RNA Polymerase B from Drosophila melanogaster Larvae

1975 • 83 citations

Structure of in-vivo transcribing chromatin as studied in simian virus 40 minichromosomes

1986 • 78 citations

Variegated chromatin structures of mouse ribosomal RNA genes

1983 • 77 citations

Nucleosome disruption precedes transcription and is largely limited to the transcribed domain of globin genes in murine erythroleukemia cells

1985 • 76 citations

Organization and expression of a-tubulin genes in Drosophila melanogaster

1982 • 74 citations

Histone synthesis and deposition in the G1 and S phases of hepatoma tissue culture cells

1985 • 69 citations

Preferential localization of variant nucleosomes near the 5'-end of the mouse dihydrofolate reductase gene.

1985 • 66 citations

High-resolution mapping of DNase I-hypersensitive sites of Drosophila heat shock genes in Drosophila melanogaster and Saccharomyces cerevisiae.

1984 • 62 citations

The Use of Formaldehyde in RNA‐Protein Cross‐linking Studies with Ribosomal Subunits from Escherichia coli

1977 • 61 citations

Chromatin structure of a hyperactive secretory protein gene (in Balbiani ring 2) of Chironomus.

1984 • 51 citations

Chromatin structure of the ribosomal RNA genes of Tetrahymena thermophila as analyzed by trimethylpsoralen crosslinking in vivo

1980 • 45 citations

Different Nucleosome Structures on Transcribing and Nontranscribing Ribosomal Gene Sequences

1979 • 42 citations

The chromatin structure of an actively expressed, single copy yeast gene

1983 • 42 citations

Absence of nucleosomes in a histone-containing nucleoprotein complex obtained by dissociation of purified SV40 virions

1982 • 41 citations

Efficient Transcription of a Compact Nucleoprotein Complex Isolated from Purified Simian Virus 40 Virions

1980 • 41 citations

Different nucleosome spacing in transcribed and non-transcribed regions of the ribosomal RNA gene inTetrahymena thermophila

1983 • 31 citations

Stability of the primary organization of nucleosome core particles upon some conformational transitions

1981 • 27 citations

Salt treatment of chromatin induces redistribution of histones

1974 • 23 citations

Hybridization selection of covalent nucleic acid-protein complexes. 2. Cross-linking of proteins to specific Escherichia coli mRNAs and DNA sequences by formaldehyde treatment of intact cells.

1985 • 23 citations

Protection of expressed immunoglobulin genes against nuclease cleavage

1983 • 17 citations

Lack of nucleosomal structure in a DNase-I-solubilized transcriptionally active chromatin fraction of Physarum polycephalum

2008 • 11 citations