Time course of flow-induced smooth muscle cell proliferation and intimal thickening in endothelialized baboon vascular grafts.

Nitric oxide release accounts for the biological activity of endothelium-derived relaxing factor

1987 • 10,774 citations

Carotid bifurcation atherosclerosis. Quantitative correlation of plaque localization with flow velocity profiles and wall shear stress.

1983 • 1,433 citations

Reductions in Arterial Diameter Produced by Chronic Decreases in Blood Flow Are Endothelium-Dependent

1986 • 1,106 citations

Inhibition of Neointimal Smooth Muscle Accumulation After Angioplasty by an Antibody to PDGF

1991 • 1,081 citations

Crucial role of endothelium in the vasodilator response to increased flow in vivo.

1986 • 991 citations

Adaptive regulation of wall shear stress to flow change in the canine carotid artery

1980 • 812 citations

Mechanisms of stenosis after arterial injury.

1983 • 765 citations

Proliferation of smooth muscle cells after vascular injury is inhibited by an antibody against basic fibroblast growth factor.

1991 • 722 citations

Platelet-derived growth factor promotes smooth muscle migration and intimal thickening in a rat model of balloon angioplasty.

1992 • 681 citations

Mechanical stress mechanisms and the cell. An endothelial paradigm.

1993 • 636 citations

A definition of the intima of human arteries and of its atherosclerosis-prone regions. A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association.

1992 • 628 citations

Role of basic fibroblast growth factor in vascular lesion formation.

1991 • 521 citations

Role of platelets in smooth muscle cell proliferation and migration after vascular injury in rat carotid artery.

1989 • 420 citations

Mechanisms of arterial graft healing. Rapid transmural capillary ingrowth provides a source of intimal endothelium and smooth muscle in porous PTFE prostheses.

1986 • 352 citations

Correlation between intimal thickness and fluid shear in human arteries

1981 • 332 citations

Tissue plasminogen activator messenger RNA levels increase in cultured human endothelial cells exposed to laminar shear stress

1990 • 276 citations

Flow stimulates endothelial cells to release a nitrovasodilator that is potentiated by reduced thiol

1990 • 260 citations

Increased blood flow inhibits neointimal hyperplasia in endothelialized vascular grafts.

1991 • 247 citations

Shear stress increases endothelial platelet-derived growth factor mRNA levels

1991 • 208 citations

Platelet-derived growth factor suppresses and fibroblast growth factor enhances cytokine-induced production of nitric oxide by cultured smooth muscle cells. Effects on cell proliferation.

1992 • 172 citations

Intimal lesion formation in rat carotid arteries after endothelial denudation in absence of medial injury.

1990 • 170 citations

Flow affects development of intimal hyperplasia after arterial injury in rats.

1992 • 161 citations

Intimal smooth muscle cell proliferation after balloon catheter injury. The role of basic fibroblast growth factor.

1992 • 161 citations

Heparin modulates the composition of the extracellular matrix domain surrounding arterial smooth muscle cells.

1990 • 147 citations

Experimental atherosclerosis at the carotid bifurcation of the cynomolgus monkey. Localization, compensatory enlargement, and the sparing effect of lowered heart rate.

1992 • 133 citations

Shear stress regulates smooth muscle proliferation and neointimal thickening in porous polytetrafluoroethylene grafts.

1991 • 133 citations

Platelet-derived growth factor activity and mRNA expression in healing vascular grafts in baboons. Association in vivo of platelet-derived growth factor mRNA and protein with cellular proliferation.

1991 • 122 citations

Flow restriction of one carotid artery in juvenile rats inhibits growth of arterial diameter

1985 • 112 citations

Arterial adaptations to altered blood flow

1991 • 106 citations

Pulsatile flow and atherosclerosis in the human carotid bifurcation: Positive correlation between plaque location and low and oscillating shear stress

1986 • 105 citations

Rapid accumulation of elastin and collagen in the aortas of sheep in the immediate perinatal period.

1991 • 100 citations

Anastomotic intimal hyperplasia: Mechanical injury or flow induced

1992 • 90 citations

Shear stress regulation of artery lumen diameter in experimental atherogenesis

1987 • 67 citations

Regional expression of the platelet-derived growth factor and its receptors in a primate graft model of vessel wall assembly.

1993 • 59 citations

Observations on human smooth muscle cell cultures from hyperplastic lesions of prosthetic bypass grafts: Production of a platelet-derived growth factor—like mitogen and expression of a gene for a platelet-derived growth factor receptor—A preliminary study

1989 • 40 citations

Kinetics of vein graft hyperplasia: Association with tangential stress

1987 • 37 citations

The Effects of Augmented Hemodynamic Forces on the Progression and Topography of Atherosclerotic Plaques

1990 • 25 citations

Fluid flow decreases preproendothelin mRNA levels and suppresses endothelin-1 peptide release in cultured human endothelial cells

1991 • 24 citations

Optimal graft diameter: Effect of wall shear stress on vascular healing

1989 • 21 citations

Mechanisms of arterial graft failure. II. Chronic endothelial and smooth muscle cell proliferation in healing polytetrafluoroethylene prostheses

1986 • 14 citations

Growth factor gene expression by intimal cells in healing polytetrafluoroethylene grafts

1990 • 7 citations

Accuracy of duplex scanning for measurement of arterial volume flow

1992 • 5 citations