Lymphocytes Expressing α1β1 Integrin (Very Late Antigen-1) in Peripheral Blood of Patients with Arthritis Are a Subset of CD45RO+ T-Cells Primed for Rapid Adhesion to Collagen IV
Data up to Jan 2025
Total Citations Per Year
Abstract
References (43)
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritis
1988 • 19,632 citations
Supramolecular assembly of basement membranes
1996 • 693 citations
Deletion of Integrin α1 by Homologous Recombination Permits Normal Murine Development but Gives Rise to a Specific Deficit in Cell Adhesion
1996 • 263 citations
Phenotypic analysis of synovial tissue and peripheral blood lymphocytes isolated from patients with rheumatoid arthritis
1988 • 248 citations
Regulation of inflammation by collagen-binding integrins α1β1 and α2β1 in models of hypersensitivity and arthritis
2000 • 215 citations
Pathogenesis of rheumatoid arthritis
1986 • 205 citations
Very late activation antigens on rheumatoid synovial fluid T lymphocytes. Association with stages of T cell activation.
1986 • 174 citations
VLA‐1: a T cell surface antigen which defines a novel late stage of human T cell activation
1985 • 151 citations
Isoforms of the CD45 common leukocyte antigen family: Markers for human T-cell differentiation
1992 • 151 citations
Flow cytometric single-cell analysis of cytokine production by CD4+ T cells in synovial tissue and peripheral blood from patients with rheumatoid arthritis
1998 • 146 citations
The role of the I domain in ligand binding of the human integrin alpha 1 beta 1.
1994 • 125 citations
Enrichment of differentiated CD45RBdim, CD27 – memory T cells in the peripheral blood, synovial fluid, and synovial tissue of patients with rheumatoid arthritis
1996 • 120 citations
PATHOGENESIS OF RHEUMATOID ARTHRITIS
2001 • 118 citations
Rheumatoid synovium is enriched in CD45RBdim mature memory T cells that are potent helpers for B cell differentiation
1992 • 96 citations
The roles of adhesion molecules and proteinases in lymphocyte transendothelial migration
1996 • 89 citations
Fibrin regulates neutrophil migration in response to interleukin 8, leukotriene B4, tumor necrosis factor, and formyl-methionyl-leucyl-phenylalanine.
1995 • 85 citations
The autoimmune pathogenesis of rheumatoid arthritis: Role of autoreactive T cells and new immunotherapies
2001 • 79 citations
T Cell Migration in Three-dimensional Extracellular Matrix: Guidance by Polarity and Sensations
2000 • 77 citations
Evidence for the continuous recruitment and activation of T cells into the joints of patients with rheumatoid arthritis
1994 • 76 citations
Type IV collagen and laminin in the synovial intimal layer: An immunohistochemical study
1990 • 70 citations
The leukocyte β1 integrins
1995 • 58 citations
Basement membrane thickening of postcapillary venules and capillaries in rheumatoid synovium
1987 • 53 citations
Subpopulations of primed t helper cells in rheumatoid arthritis
1993 • 50 citations
Cell matrix adhesion-related proteins VLA-1 and VLA-2: regulation of expression on T cells.
1987 • 44 citations
Distribution of CD45RA and CD45RO T-lymphocyte subsets in rheumatoid arthritis synovial tissue
1990 • 37 citations
Psoriatic arthritis: clinical aspects, genetics, and the role of T cells
2001 • 36 citations
Expression and functions of very late antigen 1 in inflammatory joint diseases
1991 • 33 citations
Targeting of cells involved in the pathogenesis of rheumatoid arthritis.
1999 • 30 citations
An All-<scp>d</scp> Amino Acid Peptide Model of α1(IV)531−543 from Type IV Collagen Binds the α3β1 Integrin and Mediates Tumor Cell Adhesion, Spreading, and Motility
1997 • 30 citations
The levels of memory (CD45RA?, RO+) CD4+ and CD8+ peripheral blood T-lymphocytes correlate with IgM rheumatoid factors in rheumatoid arthritis
1996 • 29 citations
Functional Role of VLA-1 (CD49A) in Adhesion, Cation-Dependent Spreading, and Activation of Cultured Human T Lymphocytes
1994 • 29 citations
P. Rambotti Lecture. Human naive and memory T cells revisited: new markers (CD31 and CD27) that help define CD4+ T cell subsets.
1993 • 27 citations
A novel monoclonal antibody, 1B3.1, binds to a new epitope of the VLA-1 molecule
1989 • 23 citations
Increased prevalence of late stage T cell activation antigen (VLA-1) in active juvenile chronic arthritis.
1987 • 20 citations
Polymyalgia rheumatica and giant cell arteritis
1995 • 19 citations
Comparative analysis of CD45RA- and CD45RO-positive CD4+T cells in peripheral blood, synovial fluid, and synovial tissue in patients with rheumatoid arthritis and osteoarthritis.
1997 • 17 citations
Abnormal distribution of CD45 isoforms expressed by CD4+ and CD8+ T cells in rheumatoid arthritis.
2000 • 16 citations
Influence of CD26 and integrins on the antigen sensitivity of human memory T cells
1996 • 16 citations
Activation antigens expressed on T-cells of the peripheral blood in Sjögren's syndrome and rheumatoid arthritis.
1990 • 12 citations
Interaction of disease-related antigen-reactive T-cell lines from multiple sclerosis patients with type IV collagen: role of integrin VLA-1 and effects of irradiation.
2002 • 11 citations
Analysis of Cell-Free Human α1 Integrin with a Monoclonal Antibody to the I-Domain: Detection in Ocular Fluid and Function as an Adhesion Substrate
2001 • 8 citations
Evidence for Selective in Vivo Expansion of Synovial Tissue‐Infiltrating CD4+CD45RO+ T‐Lymphocytes on the Basis of CDR3 Diversity
1995 • 6 citations
A novel 26 kilodalton antigen expressed on the surface membrane of activated T cells
1999 • 2 citations