Cross-linked chitosan microspheres as carriers for prolonged delivery of macromolecular drugs

Chitin in Nature and Technology

1986 • 1,021 citations

Controlled delivery systems for proteins based on poly(lactic/glycolic acid) microspheres.

1991 • 843 citations

Chitin, Chitosan, and Related Enzymes

1984 • 407 citations

Biodegradable and biocompatible poly(DL-lactide-co-glycolide) microspheres as an adjuvant for staphylococcal enterotoxin B toxoid which enhances the level of toxin-neutralizing antibodies

1991 • 370 citations

Cross-linked Chitosan Microspheres: Preparation and Evaluation as a Matrix for the Controlled Release of Pharmaceuticals

1992 • 326 citations

Lysozyme degradation of partially deacetylated chitin, its films and hydrogels

1982 • 285 citations

Biodegradable microparticles as controlled release antigen delivery systems.

1991 • 269 citations

Medical Applications of Controlled Release

2019 • 257 citations

Release of human serum albumin from poly(lactide-co-glycolide) microspheres.

1990 • 214 citations

The controlled parenteral delivery of polypeptides and proteins

1990 • 190 citations

Reconstruction of parodontal tissue with chitosan

1989 • 189 citations

Serum Albumin Beads: An Injectable, Biodegradable System for the Sustained Release of Drugs

1981 • 186 citations

Biodegradable microparticles for oral immunization

1993 • 132 citations

Controlled delivery of diphtheria toxoid using biodegradable poly(D,L-lactide) microcapsules.

1991 • 95 citations

Chitin is an effective material for sutures

1986 • 70 citations

Enhanced microbial cell lysis by the use of lysozyme immobilized on different carriers

1993 • 61 citations

Stability of atriopeptin III in poly(d,l-lactide-co-glycolide) microspheres

1991 • 61 citations

A formulation method using D, L-lactic acid oligomer for protein release with reduced initial burst

1993 • 56 citations

In vivo characteristics of low molecular weight copoly(L-lactic acid/glycolic acid) formulations with controlled release of luteinizing hormone-releasing hormone agonist

1989 • 49 citations

Opportunities and challenges in the design of implantable biodegradable polymeric systems for the delivery of antimicrobial agents and vaccines

1987 • 48 citations

Immunogenicity studies on diphtheria toxoid loaded biodegradable microspheres

1992 • 33 citations

Production of cellobiose by enzymatic hydrolysis: Removal of β‐glucosidase from cellulase by affinity precipitation using chitosan

1993 • 27 citations

Effects of Intense Noncavitating Ultrasound on Selected Enzymes

1968 • 26 citations

Preparation of hydrogel beads from crosslinked poly(methyl methacrylate) microspheres by alkaline hydrolysis

1990 • 26 citations

Controlled-Release and Localized Targeting of Interferons

1986 • 15 citations