The relationship between transformation and somatic mutation in human and Chinese hamster cells

Mutation and Cancer: Statistical Study of Retinoblastoma

1971 • 7,335 citations

MUTATIONS OF BACTERIA FROM VIRUS SENSITIVITY TO VIRUS RESISTANCE

1943 • 3,852 citations

Carcinogens are Mutagens: A Simple Test System Combining Liver Homogenates for Activation and Bacteria for Detection

1973 • 2,275 citations

Chemical Carcinogenesis

1975 • 741 citations

Two Types of Ribosome in Mouse–Hamster Hybrid Cells

1971 • 577 citations

A Two-stage Theory of Carcinogenesis in Relation to the Age Distribution of Human Cancer

1957 • 553 citations

<italic>In Vitro</italic> Transformation of Normal Cells to Tumor Cells by Carcinogenic Hydrocarbons<xref ref-type="fn" rid="FN2">2</xref>

1965 • 400 citations

Ouabain-resistant mutants of mouse and hamster cells in culture

1974 • 393 citations

Mutation and childhood cancer: a probabilistic model for the incidence of retinoblastoma.

1975 • 353 citations

The mechanism of carcinogenesis, A study of the significance of cocarcinogenic action and related phenomena

1941 • 309 citations

Malignant neoplasms in the families of patients with ataxia-telangiectasia.

1976 • 285 citations

Fanconi's Anaemia in the Genetics of Neoplasia

1971 • 263 citations

Mutation and Human Cancer

1973 • 210 citations

Quantitative Studies of <italic>In Vitro</italic> Transformation by Chemical Carcinogens

1969 • 197 citations

The two “hit” and multiple “hit” theories of carcinogenesis.

1969 • 158 citations

Mutability of different genetic loci in mammalian cells by metabolically activated carcinogenic polycyclic hydrocarbons.

1976 • 148 citations

Isolation of ouabain-resistant human diploid fibroblasts

1974 • 127 citations

Somatic mutation as the basis for malignant transformation of BHK cells by chemical carcinogens

1976 • 120 citations

Cell susceptibility to transformation and cytotoxicity by the carcinogenic hydrocarbon benzo[a]pyrene.

1966 • 116 citations

Two-stage Malignant Transformation of Rat Fibroblasts in Tissue Culture

1974 • 107 citations

Transformation of Mammalian Cells in vitro by Low Doses of X-rays

1973 • 93 citations

Metabolism of polycyclic aromatic hydrocarbons in cell cultuires.

1971 • 77 citations

X-ray-induced mutation to 6-thioguanine resistance in cultured human diploid fibroblasts

1976 • 76 citations

Transformation and Neoplastic Development <italic>In Vitro</italic> of Hamster Embryonic Cells by 4-Nitroquinoline-1-Oxide and Its Derivatives<xref ref-type="fn" rid="FN2">2</xref><xref ref-type="fn" rid="FN3">3</xref>

1968 • 74 citations

Differential genetic susceptibility of cultured human skin fibroblasts to transformation by Kirsten murine sarcoma virus

1977 • 61 citations

The Mechanism of Carcinogenesis

1972 • 54 citations

Carcinogenesis in vitro

1975 • 52 citations

Spontaneous transformation of human skin fibroblasts derived from neoplastic patients

1976 • 47 citations

Transfer of codominant markers by isolated metaphase chromosomes in Chinese hamster ovary cells.

1977 • 40 citations

Transfer of anchorage independence by isolated metaphase chromosomes in hamster cells

1977 • 36 citations

Urethan carcinogenesis and nucleic acid metabolism: factors influencing lung adenoma induction.

1966 • 34 citations

The isolation and preliminary characterisation of 6-thioguanine-resistant mutants of human diploid fibroblasts

1976 • 29 citations

Chapter 11 Agar Plate Culture and Lederberg-Style Replica Plating of Mammalian Cells

1975 • 26 citations

Characterisation of human cells transformed in vitro by urethane

1975 • 24 citations

Transfer of the marker for morphologically transformed phenotype by isolated metaphase chromosomes in hamster cells

1978 • 19 citations

X-ray dose response for mutation to fructose utilisation in cultured diploid human fibroblasts

1974 • 18 citations

Linkage of markers controlling consecutive biochemical steps in CHO cells as demonstrated by chromosome transfer

1977 • 17 citations

Some aspects of the basic mechanisms of chemical carcinogenesis

1977 • 8 citations

Transfer of codominant markers by isolated metaphase chromosomes in Chinese hamster ovary cells

1977 • 6 citations

Genetic analysis by chromosome-mediated gene transfer in hamster cells.

1977 • 3 citations

Cell membrane systems

1974 • 1 citations