Identification of Sequence Variants and Analysis of the Role of the Catechol-O-Methyl-Transferase Gene in Schizophrenia Susceptibility

Regression Models for Ordinal Data

1980 • 3,830 citations

Human catechol-O-methyltransferase pharmacogenetics: description of a functional polymorphism and its potential application to neuropsychiatric disorders

1996 • 1,780 citations

Kinetics of Human Soluble and Membrane-Bound Catechol O-Methyltransferase: A Revised Mechanism and Description of the Thermolabile Variant of the Enzyme

1995 • 1,152 citations

Schizophrenia susceptibility associated with interstitial deletions of chromosome 22q11.

1995 • 634 citations

Prevalence of 22q11 microdeletions in DiGeorge and velocardiofacial syndromes: implications for genetic counselling and prenatal diagnosis.

1993 • 495 citations

Psychotic Illness in Patients Diagnosed with Velo-Cardio-Facial Syndrome and Their Relatives

1994 • 434 citations

Sequential strategy to identify a susceptibility gene for schizophrenia: Report of potential linkage on chromosome 22q12‐q13.1: Part 1

1994 • 387 citations

Obsessive-compulsive disorder with psychotic features: a phenomenologic analysis

1986 • 325 citations

Chromosomal mapping of the human catechol-O-methyltransferase gene to 22q11.1→q11.2

1992 • 295 citations

Inheritance of low erythrocyte catechol-o-methyltransferase activity in man.

1977 • 248 citations

Optimization of the single-strand conformation polymorphism (SSCP) technique for detection of point mutations

1993 • 238 citations

A combined analysis of D22S278 marker alleles in affected sib-pairs: Support for a susceptibility locus for schizophrenia at chromosome 22q12

1996 • 232 citations

Minor Physical Anomalies in Schizophrenia

1989 • 220 citations

Obsessive and compulsive symptoms in chronic schizophrenia

1995 • 207 citations

Obsessive compulsive disorder with psychotic features.

1993 • 199 citations

Genomic scan for genes predisposing to schizophrenia

1994 • 170 citations

The Incidence of Minor Physical Anomalies in Adult Male Schizophrenics

1983 • 152 citations

No evidence for allelic association between schizophrenia and a polymorphism determining high or low catechol O-methyltransferase activity

1996 • 149 citations

Dopaminergic mechanisms in the pathogenesis of schizophrenia ¹

1992 • 137 citations

Minor physical anomalies in alcoholic and schizophrenic adults and hyperactive and autistic children

1982 • 135 citations

Linkage studies on chromosome 22 in familial schizophrenia

1995 • 87 citations

Obsessions and compulsions in the community

1994 • 65 citations

Potential linkage disequilibrium between schizophrenia and locus D22S278 on the long arm of chromosome 22

1995 • 58 citations

Potential linkage for schizophrenia on chromosome 22q12‐q13: A replication study

1995 • 58 citations

Analysis of case-control/family sampling design

1996 • 55 citations

Schizophrenia: Gender and familial risk

1992 • 51 citations

Estimating effects of proband characteristics on familial risk: II. The association between age at onset and familial risk in the Maryland schizophrenia sample

1991 • 50 citations

Detection of single base mismatches of thymine and cytosine residues by potassium permanganate and hydroxylamine in the presence of tetralkylammonium salts

1990 • 35 citations

Minor physical anomalies in schizophrenia

1992 • 24 citations

Schizophrenia: genetic tools for unraveling the nature of a complex disorder.

1995 • 19 citations

Erythrocyte catechol O-methyltransferase activity in schizophrenia: analysis of family data

1984 • 15 citations

Erythrocyte catechol‐O‐methyltransferase activity in related families with schizophrenia

1981 • 10 citations

Dopamlne metabolism in red blood cells in schizophrena

1981 • 7 citations

Erythrocyte catechol‐O‐methyltransferase activity in psychotic twins

1981 • 5 citations

Royal academy of medicine in ireland section of dermatology

1993 • 4 citations