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1995 • 2,090 citations

Brain-Derived Neurotrophic Factor Produces Antidepressant Effects in Behavioral Models of Depression

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MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder

1995 • 1,567 citations

Decreased Dendritic Spine Density on Prefrontal Cortical Pyramidal Neurons in Schizophrenia

2000 • 1,565 citations

Stress and glucocorticoids affect the expression of brain-derived neurotrophic factor and neurotrophin-3 mRNAs in the hippocampus

1995 • 1,429 citations

The Control of Progesterone Secretion During the Estrous Cycle and Early Pseudopregnancy in the Rat: Prolactin, Gonadotropin and Steroid Levels Associated with Rescue of the Corpus Luteum of Pseudopregnancy¹²

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Stress induces atrophy of apical dendrites of hippocampal CA3 pyramidal neurons

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Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat.

1992 • 1,178 citations

Increased hippocampal bdnf immunoreactivity in subjects treated with antidepressant medication

2001 • 1,137 citations

Naturally occurring fluctuation in dendritic spine density on adult hippocampal pyramidal neurons

1990 • 1,080 citations

Roles of estradiol and progesterone in regulation of hippocampal dendritic spine density during the estrous cycle in the rat

1993 • 1,066 citations

Exposure to excess glucocorticoids alters dendritic morphology of adult hippocampal pyramidal neurons

1990 • 1,013 citations

Estrogen Replacement Therapy for Treatment of Mild to Moderate Alzheimer Disease

2000 • 985 citations

Estradiol mediates fluctuation in hippocampal synapse density during the estrous cycle in the adult rat [published erratum appears in J Neurosci 1992 Oct;12(10):following table of contents]

1992 • 959 citations

Brain-derived neurotrophic factor in the control human brain, and in Alzheimer’s disease and Parkinson’s disease

2001 • 851 citations

Homeostatic plasticity in neuronal networks: the more things change, the more they stay the same

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Reduced dendritic spine density on cerebral cortical pyramidal neurons in schizophrenia

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PSYCHONEUROENDOCRINOLOGY OF DEPRESSION

1998 • 659 citations

Neuronal plasticity and survival in mood disorders

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Invited Review: Estrogens effects on the brain: multiple sites and molecular mechanisms

2001 • 645 citations

Hormone Replacement Therapy and Cognition

2001 • 643 citations

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1991 • 578 citations

Identification of a putative estrogen response element in the gene encoding brain-derived neurotrophic factor.

1995 • 542 citations

Neurotrophins and depression

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2001 • 477 citations

Oestrogen as a neuroprotective hormone

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Brain-derived neurotrophic factor promotes the survival and sprouting of serotonergic axons in rat brain

1995 • 470 citations

Sex and depression in the national comorbidity survey. II: Cohort effects

1994 • 469 citations

Estradiol Increases Dendritic Spine Density by Reducing GABA Neurotransmission in Hippocampal Neurons

1998 • 460 citations

BDNF Has Opposite Effects on the Quantal Amplitude of Pyramidal Neuron and Interneuron Excitatory Synapses

1998 • 460 citations

5-HT_2AReceptor-Mediated Regulation of Brain-Derived Neurotrophic Factor mRNA in the Hippocampus and the Neocortex

1997 • 448 citations

Estradiol Enhances Learning and Memory in a Spatial Memory Task and Effects Levels of Monoaminergic Neurotransmitters

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The nature of the effect of female gonadal hormone replacement therapy on cognitive function in post-menopausal women: a meta-analysis

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Role for brain-derived neurotrophic factor in learning and memory

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Structural Abnormalities of Subicular Dendrites in Subjects With Schizophrenia and Mood Disorders

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Destabilization of Cortical Dendrites and Spines by BDNF

1999 • 352 citations

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2000 • 341 citations

Abnormal expression of brain-derived neurotrophic factor and its receptor in the corticolimbic system of schizophrenic patients

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Radioligand binding evidence implicates the brain 5-HT2 receptor as a site of action for LSD and phenylisopropylamine hallucinogens

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A meta-analysis of the effect of hormone replacement therapy upon depressed mood

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Estrogen and exercise interact to regulate brain‐derived neurotrophic factor mRNA and protein expression in the hippocampus

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Estrogen, serotonin, and mood disturbance: where is the therapeutic bridge?

1998 • 278 citations

Estradiol alleviates depressive-like symptoms in a novel animal model of post-partum depression

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Levels of trkA and BDNF mRNA, but not NGF mRNA, fluctuate across the estrous cycle and increase in response to acute hormone replacement

1998 • 260 citations

Neurotrophins and activity-dependent plasticity

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Estrogen Deficiency in Severe Postpartum Depression

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Neurotrophins and hippocampal synaptic transmission and plasticity

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Brain-derived neurotrophic factor mediates estradiol-induced dendritic spine formation in hippocampal neurons

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Novel therapeutic approaches beyond the serotonin receptor

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Modulation by estradiol of serotonin receptors in brain

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Estrogen Regulates Functional Inhibition of Hippocampal CA1 Pyramidal Cells in the Adult Female Rat

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Estrogen and Basal Forebrain Cholinergic Neurons: Implications for Brain Aging and Alzheimer's Disease-Related Cognitive Decline

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Distribution and differences of estrogen receptor beta immunoreactivity in the brain of adult male and female rats

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Estrogen increases the density of 5-Hydroxytryptamine2A receptors in cerebral cortex and nucleus accumbens in the female rat

1995 • 195 citations

Ovarian Steroid Regulation of Tryptophan Hydroxylase mRNA Expression in Rhesus Macaques

1996 • 193 citations

Treatment with estrogen and progesterone affects relative levels of brain-derived neurotrophic factor mRNA and protein in different regions of the adult rat brain

1999 • 187 citations

Estradiol-17β increase serotonin transporter (SERT) mRNA levels and the density of SERT-binding sites in female rat brain

1997 • 187 citations

High levels of estradiol disrupt conditioned place preference learning, stimulus response learning and reference memory but have limited effects on working memory

2001 • 173 citations

Brain-derived neurotrophic factor and tyrosine kinase receptor TrkB in rat brain are significantly altered after haloperidol and risperidone administration

2000 • 170 citations

Effects of Estrogen Antagonists and Agonists on the ACTH Response to Restraint Stress in Female Rats

2001 • 165 citations

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Testosterone as well as estrogen increases serotonin2A receptor mRNA and binding site densities in the male rat brain

1998 • 155 citations

Effect of chronic restraint stress on dendritic spines and excrescences of hippocampal CA3 pyramidal neurons—a quantitative study

1995 • 149 citations

Role of 5-HT2A receptors in the stress-induced down-regulation of brain-derived neurotrophic factor expression in rat hippocampus

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Manipulations of brain 5-HT levels affect gene expression for BDNF in rat brain

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Granule Cells in Aging Rats Are Sexually Dimorphic in Their Response to Estradiol

1999 • 135 citations

Regional and Selective Effects of Oestradiol and Progesterone on NMDA and AMPA Receptors in the Rat Brain

2000 • 127 citations

Effect of chronic restraint stress and tianeptine on growth factors, growth-associated protein-43 and microtubule-associated protein 2 mRNA expression in the rat hippocampus

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BDNF induction of tryptophan hydroxylase mRNA levels in the rat brain

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Effects of chronic 17?-estradiol treatment on the serotonin 5-HT1A receptor mRNA and binding levels in the rat brain

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Positive Treatment Effect of Estradiol in Postpartum Psychosis

2000 • 107 citations

Region- and peptide-specific regulation of the neurotrophins by estrogen

2000 • 105 citations

Modulation by Estrogen-Receptor Directed Drugs of 5-Hydroxytryptamine-2A Receptors in Rat Brain

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Gonadal hormones modulate 5-hydroxytryptamine2A receptors: emphasis on the rat frontal cortex

1998 • 97 citations

Interactions between 5-hydroxytryptamine receptor subtypes: Is a disturbed receptor balance contributing to the symptomatology of depression in humans?

1995 • 85 citations

Serotonin2 receptor-mediated excitation of interneurons in piriform cortex: Antagonism by atypical antipsychotic drugs

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Brain-derived neurotrophic factor prevents neuronal cell death induced by corticosterone

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Endocrine and receptor pharmacology of serotonergic anxiolytics, antipsychotics and antidepressants

1992 • 72 citations

PSYCHONEUROENDOCRINOLOGY OF DEPRESSION

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Length of Postovariectomy Interval and Age, but Not Estrogen Replacement, Regulate N-Methyl-d-Aspartate Receptor mRNA Levels in the Hippocampus of Female Rats

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Hormone Replacement Therapy and Cognition

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Pharmacological effects of MDL 11,939: A selective, centrally acting antagonist of 5‐HT₂ receptors

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Hypothalamic-Pituitary-Gonadal Axis

1984 • 15 citations