Functional and non-functional joining in immunoglobulin light chain genes of a mouse myeloma

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

1980 • 15,302 citations

Ovalbumin gene: evidence for a leader sequence in mRNA and DNA sequences at the exon-intron boundaries.

1978 • 1,117 citations

Sequences at the somatic recombination sites of immunoglobulin light-chain genes

1979 • 859 citations

Sequences of mouse immunoglobulin light chain genes before and after somatic changes

1978 • 495 citations

Sequences of five potential recombination sites encoded close to an immunoglobulin kappa constant region gene.

1979 • 472 citations

CELLULAR LOCALIZATION OF IMMUNOGLOBULINS WITH DIFFERENT ALLOTYPIC SPECIFICITIES IN RABBIT LYMPHOID TISSUES

1965 • 444 citations

Organisation and sequences at the 5′ end of a cloned complete ovalbumin gene

1979 • 340 citations

A κ-immunoglobulin gene is formed by site-specific recombination without further somatic mutation

1979 • 283 citations

Antigen-Binding Myeloma Proteins of Mice

1978 • 272 citations

Activity of multiple light chain genes in murine myeloma cells producing a single, functional light chain

1980 • 228 citations

RABBIT LYMPHOID CELLS DIFFERENTIATED WITH RESPECT TO α-, γ-, AND µ- HEAVY POLYPEPTIDE CHAINS AND TO ALLOTYPIC MARKERS A<scp>A</scp>1 AND A<scp>A</scp>2

1966 • 212 citations

Improved computer program data for the resolution and fractionation of macromolecules by isokinetic sucrose density gradient sedimentation

1974 • 172 citations

Transcription of mouse kappa chain genes: implications for allelic exclusion.

1980 • 167 citations

A mutant immunoglobulin light chain is formed by aberrant DNA- and RNA-splicing events

1980 • 158 citations

Organization and complete sequence of identical embryonic and plasmacytoma kappa V-region genes.

1980 • 138 citations

DNA clones containing mouse immunoglobulin kappa chain genes isolated by in vitro packaging into phage lambda coats.

1978 • 98 citations

Primary structures of N-terminal extra peptide segments linked to the variable and constant regions of immunoglobulin light chain precursors: implications on the organization and controlled expression of immunoglobulin genes

1978 • 80 citations

A rearranged DNA sequence possibly related to the translocation of immunoglobulin gene segments

1980 • 75 citations

Synthesis of a carboxyl-terminal (constant region) fragment of the immunoglobin light chain by a mouse myeloma cell line

1974 • 68 citations

Rearrangement of immunoglobulin genes

1979 • 52 citations

Cloned MPC 11 myeloma cells express two kappa genes: a gene for a complete light chain and a gene for a constant region polypeptide

1977 • 51 citations

Two rearranged immunoglobulin kappa light chain genes in one mouse myeloma

1980 • 45 citations

V–J joining of immunoglobulin κ genes only occurs on one homologous chromosome

1980 • 41 citations

An unusual translocation of immunoglobulin gene segments in variants of the mouse myeloma MPC11

1980 • 40 citations

Cloning of V region fragments from mouse liver DNA and localization of repetitive DNA sequences in the vicinity of immunoglobulin gene segments

1980 • 29 citations

Determination of the Primary Structure of a Mouse IgG2a Immunoglobulin

1975 • 29 citations

Cloning of immunoglobulin kappa light chain genes from mouse liver and myeloma MOPC 173

1979 • 29 citations

Myeloma proteins from NZB and BALB/c mice: structural and functional differences.

1979 • 23 citations

Immunoglobulin gene rearrangements in hybridoma cells.

1980 • 10 citations