Indicators of periodontal disease activity: an evaluation

A study of the bacteria associated with advancing periodontitis in man

1979 • 946 citations

Subgingival microflora and periodontal disease

1979 • 822 citations

New concepts of destructive periodontal disease

1984 • 736 citations

Relative distribution of bacteria at clinically healthy and periodontally diseased sites in humans*

1978 • 708 citations

Actinobacillus actinomycetemcomitans in Human Periodontal Disease: a Cross-Sectional Microbiological Investigation

1980 • 665 citations

Microbiology of Periodontal Disease—Present Status and Future Considerations

1977 • 643 citations

Patterns of progression and regression of advanced destructive periodontal disease

1982 • 627 citations

Bacteriology of severe periodontitis in young adult humans

1982 • 485 citations

Predominant cultivable microbiota in periodontosis

1977 • 447 citations

The Case for Periodontosis as a Clinical Entity

1971 • 443 citations

Comparative bacteriology of juvenile periodontitis

1985 • 431 citations

The Bacteriology of Acute Necrotizing Ulcerative Gingivitis

1982 • 360 citations

Bacteriology of moderate (chronic) periodontitis in mature adult humans

1983 • 359 citations

Black-pigmented Bacteroides spp. in the human oral cavity

1981 • 336 citations

Serum antibodies to oral Bacteroides asaccharolyticus (Bacteroides gingivalis): relationship to age and periondontal disease

1981 • 302 citations

Neutrophil Chemotaxis Dysfunction in Human Periodontitis

1980 • 299 citations

Distribution of certain subgingival microbial species in selected periodontal conditions

1984 • 288 citations

Defective neutrophil chemotaxis in juvenile periodontitis

1977 • 266 citations

Bactericidal Activity of Human Lactoferrin: Differentiation from the Stasis of Iron Deprivation

1982 • 257 citations

Crevicular fluid updated.

1983 • 254 citations

Crevicular fluid prostaglandin E levels as a measure of the periodontal disease status of adult and juvenile periodontitis patients

1984 • 204 citations

Flurbiprofen: A Potent Inhibitor of Alveolar Bone Resorption in Beagles

1985 • 192 citations

Corynebacterium diphtheriae and Its Relatives

1970 • 178 citations

An ELISA for measuring serum antibodies to Actinobacillus actinomycetemcomitans

1980 • 174 citations

Increased thymocyte-activating factor in human gingival fluid during gingival inflammation

1982 • 170 citations

The borderland between caries and periodontal disease

1979 • 169 citations

The microbiology of ligature‐induced periodontitis in the cynomolgus monkey

1981 • 162 citations

Comparative antibody titers to Actinobacillus actinomycetemcomitans in juvenile periodontitis, chronic periodontitis and periodontally healthy subjects

1981 • 161 citations

The origin and variation in number of leukocytes in the human saliva

1970 • 161 citations

Butyrate and propionate: important components of toxic dental plaque extracts

1981 • 156 citations

Genetic Heterogeneity in Bacteroides asaccharolyticus (Holdeman and Moore 1970) Finegold and Barnes 1977 (Approved Lists, 1980) and Proposal of Bacteroides gingivalis sp. nov. and Bacteroides macacae (Slots and Genco) comb. nov.

1980 • 155 citations

Measurement of prostaglandin E in crevicular fluid

1981 • 155 citations

A crevicular washing method for investigating immune components of crevicular fluid in man

1976 • 143 citations

Relationship Between Attachment Loss and Precipitating Serum Antibody to Actinobacillus actinomycetemcomitans in Adolescents and Young Adults Having Severe Periodontal Destruction,

1982 • 143 citations

A longitudinal microbiological investigation of Actinobacillus actinomycetemcomitans and Eikenella corrodens in juvenile periodontitis

1984 • 141 citations

Modulation of neutrophil function by lysozyme. Potential negative feedback system of inflammation.

1979 • 136 citations

Clinical, microbiological and immunological features associated with the treatment of active periodontosis lesions

1984 • 133 citations

Association of Lactoferrin with Lysozyme in Granules of Human Polymorphonuclear Leukocytes

1972 • 131 citations

Some Characteristics of Collagenase Activity in Gingival Crevicular Fluid and Its Relationship to Gingival Diseases in Humans

1976 • 131 citations

Gingival Fluid and Serum in Periodontal Diseases: II. Evidence for Cleavage of Complement Components C3, C3 Proactivator (Factor B) and C4 in Gingival Fluid

1977 • 117 citations

Effect of subgingival scaling on systemic antibody responses to oral microorganisms

1985 • 115 citations

Development of a Biochemical Profile for Gingival Crevicular Fluid: Methodological Considerations and Evaluation of Collagen‐Degrading and Ground Substance‐Degrading Enzyme Activity during Experimental Gingivitis

1985 • 109 citations

Sulcular polymorphonuclear leucocytes and gingival exudate during experimental gingivitis in man

1980 • 108 citations

Increase of free collagenase and neutral protease activities in the gingival crevice during experimental gingivitis in man

1979 • 108 citations

Bactericidal Antibody in Mammalian Serum to Obligatorily Anaerobic Gram-Negative Bacteria

1966 • 102 citations

Glycosaminoglycans in human gingival crevicular fluid as indicators of active periodontal disease

1985 • 98 citations

The Chain that Links the Heart to the Throat

1973 • 94 citations

Endotoxin Determinations in Gingival Inflammation

1972 • 88 citations

Bacterial IgG and IgM Antibody Titers in Acute Necrotizing Ulcerative Gingivitis

1983 • 88 citations

Lysozyme and Lactoferrin Quantitation in the Crevicular Fluid

1983 • 86 citations

The possible role of hydrogen sulfide in human periodontal disease. I. Hydrogen sulfide production in periodontal pockets.

1967 • 83 citations

A Comparative Study of the Lysozyme Activity of Human Gingival Pocket Fluid, Serum, and Saliva

1964 • 76 citations

Differential dark field microscopy of subgingival bacteria as an aid in selecting recall intervals: results after 18 months

1982 • 73 citations

Aspartate Aminotransferase Increases in Crevicular Fluid During Experimental Periodontitis in Beagle Dogs

1984 • 72 citations

Alkaline phosphatase in human gingival fluid and its relation to periodontitis

1970 • 68 citations

Lactate Dehydrogenase, β‐Glucuronidase and Arylsulfatase Activity in Gingival Crevicular Fluid Associated with Experimental Gingivitis in Man

1985 • 68 citations

The electrophoretic detection of acidic glycosaminoglycans in human gingival sulcus fluid

1982 • 66 citations

The Role of Endotoxin in Periodontal Disease III. Correlation of the Amount of Endotoxin in Human Gingival Exudate with the Histologic Degree of Inflammation

1971 • 64 citations

Effect of Topical Acidulated Phosphate Fluoride on Percentage of Streptococcus mutans and Streptococcus sanguis in Plaque

1975 • 64 citations

Beta-glucuronidase correlated with inflammation in the exudate from human gingiva

1970 • 63 citations

Possible role of lysosomal enzymes in the pathogenesis of periodontitis: A study on cathepsin D in human gingival fluid

1972 • 59 citations

Quantitative evaluation of gingivitis and periodontal disease. I. The orogranulocytic migratory rate.

1968 • 59 citations

Antibody to Leptotrichia buccalis in human sera

1965 • 57 citations

The Role of Endotoxin in Periodontal Disease II. Correlation of the Quantity of Endotoxin in Human Gingival Exudate with the Clinical Degree of Inflammation

1970 • 55 citations

Role for Endotoxin and Complement in Periodontal Tissue Destruction

1972 • 50 citations

Hydrogen Sulfide Production From Gingival Crevicular Fluid

1980 • 49 citations

Immune response and periodontal bone loss in germfree rats immunized and infected with Actinobacillus actinomycetemcomitans

1983 • 47 citations

Studies on the Anaerobic Bacterial Flora of Suppurative Periodontitis

1942 • 46 citations

Quantitative Differences in Spirochetal Antibody Observed in Periodontal Disease

1968 • 44 citations

Correlation Between Gingivitis and Orogranulocytic Migratory Rate

1969 • 42 citations

Gingival sulcular leukocytes in periodontitis and in experimental gingivitis in humans

1984 • 41 citations

Activity of human serum immunoglobulins to seven anaerobic oral bacterie before and after periodontal treatment

1982 • 40 citations

Relation of the Orogranulocytic Migratory Rate to Periodontal Disease and Blood Leukocyte Count: A Clinical Study

1972 • 40 citations

Reliability of volume measurements with the new Periotron® 6000

1984 • 39 citations

The Role of Endotoxin in Periodontal Disease. I. A Reproducible, Quantitative Method for Determining the Amount of Endotoxin in Human Gingival Exudate

1969 • 38 citations

Comparative Differential Dark‐Field Microscopy of Subgingival Bacteria From Tooth Surfaces With Recent Evidence of Recurring Periodontitis and From Nonaffected Surfaces

1984 • 34 citations

Diphtheria: Its Bacteriology, Pathology and Immunology

1924 • 33 citations

The response of human sulcular leucocytes to a chemotactic challenge.

1981 • 31 citations

Bacteriological studies of subgingival plaque in a periodontitis‐resistant population

1985 • 30 citations

Lysozyme concentrations in the gingival crevice and at other oral sites in human subjects with and without gingivitis

1976 • 29 citations

ELISA and conventional techniques for identification of black‐pigmented Bacteroides isolated from Periodontal pockets

1983 • 29 citations

A comparison of 3 systems for quantifying gingival crevicular fluid with respect to linearity and the effects of qualitative differences in fluids

1984 • 29 citations

Oral implantation of Bacteroides asaccharolyticus and Eikenella corrodens in conventional hamsters

1982 • 27 citations

The effect of collagenase‐inhibitor complexes on collagenolytic activity of normal and inflamed gingival tissue

1973 • 27 citations

The role for butyrate and propionate in mediating HeLa-cells growth inhibition by human dental plaque fluid from adult periodontal disease

1985 • 27 citations

Increase of extracellular cathepsin D activity in gingival washings during experimental gingivitis in man

1977 • 26 citations

Identification of a Cathepsin B-like Protease in the Crevicular Fluid of Gingivitis Patients

1983 • 26 citations

Polyamines of Dental Plaque in Caries-resistant vs. Caries-susceptible Adults

1985 • 24 citations

Increase of Endotoxin Concentration in Gingival Washings During Experimental Gingivitis in Man

1979 • 22 citations

Immunochemical study of host proteins in human supragingival compared with denture plaque

1984 • 21 citations

Arylsulphatase activity in human gingival crevicular fluid

1984 • 21 citations

Oral leukocytes and gingivitis in the primary dentition

1974 • 21 citations

Enzyme Activity in Periodontal Disease

1970 • 20 citations

In Vivo Crevicular Leucocyte Response in Humans to a Chemotactic Challenge: Effects of Periodontal Diseases

1984 • 20 citations

Bacterial enzymes and viable counts in crevices of noninflamed and inflamed gingiva

1976 • 19 citations

Periodontal bone loss in ovalbumin sensitized germfree rats fed antigen-free diet with ovalbumin

1983 • 17 citations

Neuraminidase activity in human crevicular fluid

1983 • 16 citations

Acute ulcerative gingivitis. An immunofluorescent investigation.

1966 • 16 citations

Fluide gingival, inflammation gingivale, profondeur des poches et perte osseuse.

1972 • 15 citations

The role of complement in initial gingivitis

1976 • 13 citations

Lactate dehydrogenase isoenzymes in gingival fluid

1972 • 11 citations

Bacterial Antibody Titers in Ligature‐Induced Periodontitis in Beagle Dogs

1983 • 10 citations

Evaluation of 2-Phosphono-butane 1,2,4 Tricarboxylate as a Crystal Growth Inhibitor in vitro and in vivo

1985 • 10 citations

Microscopic evaluation of root surface associations in vivo

1984 • 10 citations

Detection and quantitation of Bacteroides gingivalis in bacterial mixtures by means of flow cytometry

1984 • 9 citations

Isoenzymes of lactic dehydrogenase in human gingival fluid.

1972 • 9 citations

Evaluation of an Oral Disease Control Program Administered to a Clinic Population at a Suburban Dental School

1980 • 6 citations

Determination of periodontal disease activity by a bone resorption assay

1984 • 3 citations