Antihemophilic Factor (Factor VIII)

Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial Cells

1973 • 1,303 citations

Immunologic differentiation of classic hemophilia (factor VIII deficiency) and von Willebrand's disease

1971 • 660 citations

Acquired inhibitors of blood coagulation.

1972 • 531 citations

MEASUREMENT OF PLATELET ADHESIVENESS. A SIMPLE IN VITRO TECHNIQUE DEMONSTRATING AN ABNORMALITY IN VON WILLEBRAND'S DISEASE.

1963 • 479 citations

Ristocetin - A New Tool in the Investigation of Platelet Aggregation

1971 • 453 citations

Christmas Disease

1952 • 424 citations

High-potency Antihæmophilic Factor Concentrate prepared from Cryoglobulin Precipitate

1964 • 300 citations

Circulating anticoagulants: a study of 40 cases and a review of the literature.

1961 • 285 citations

Plasma Throinboplastin Component (PTC) Deficiency: A New Disease Resembling Hemophilia

1952 • 251 citations

Defective Ristocetin-Induced Platelet Aggregation in von Willebrand's Disease and its Correction by Factor VIII

1973 • 222 citations

Isolation and Characterization of Human Factor VIII (Antihemophilic Factor)

1973 • 216 citations

Antihemophilic Factor: Separation of an Active Fragment Following Dissociation by Salts or Detergents

1972 • 193 citations

Detection of carriers of classic hemophilia using an immunologic assay for antihemophilic factor (factor VIII)

1971 • 189 citations

Relationship of sialic acid to function and in vivo survival of human factor VIII/von Willebrand factor protein.

1977 • 184 citations

Immunological Characterization of Purified Anti-Haemophilic Factor A (Factor VIII) which corrects Abnormal Platelet Retention in Von Willebrand's Disease

1972 • 167 citations

HEMOPHILIA. II. SOME PROPERTIES OF A SUBSTANCE OBTAINED FROM NORMAL HUMAN PLASMA EFFECTIVE IN ACCELERATING THE COAGULATION OF HEMOPHILIC BLOOD

1937 • 165 citations

Activated Prothrombin Concentrate for Patients with Factor VIII Inhibitors

1974 • 163 citations

CHROMOSOMAL AND SUBCHROMOSOMAL INACTIVATION

1968 • 160 citations

The Subunit Structure of Normal and Hemophilic Factor VIII

1973 • 151 citations

Genetic Variants of von Willebrand's Disease

1972 • 144 citations

Immunologic Studies of Antihemophilic Factor (AHF, Factor VIII): Cross-Reacting Material in a Genetic Variant of Hemophilia A

1968 • 143 citations

Epsilon‐Aminocaproic Acid Therapy for Dental Extractions in Haemophilia and Christmas Disease: A Double Blind Controlled Trial

1971 • 140 citations

Hemophilia in the Talmud and Rabbinic Writings

1969 • 125 citations

MOLECULAR STRUCTURAL STUDIES OF HUMAN FACTOR VIII*

1975 • 115 citations

A Variant of Factor VIII Related Antigen

1974 • 114 citations

HEMOPHILIA. I. THE ABNORMAL COAGULATION OF THE BLOOD AND ITS RELATION TO THE BLOOD PLATELETS

1936 • 109 citations

CONTRIBUTION TO THE PATHOGENESIS OF HEMOPHILIA

1947 • 107 citations

Studies on the purification and characterization of human factor VIII

1972 • 107 citations

Über hereditäre Pseudohämophilie.

1931 • 102 citations

Factor VIII Detection by Hemagglutination Inhibition: Hemophilia A and von Willebrand's Disease

1971 • 101 citations

The Fate of Prothrombin and Factors VIII, IX and X Transfused to Patients Deficient in these Factors

1963 • 94 citations

FACTOR VIII COAGULANT ACTIVITY AND FACTOR VIII-LIKE ANTIGEN: INDEPENDENT MOLECULAR ENTITIES

1973 • 93 citations

Hemorrhagic Disease in an Infant Due to Deficiency of a Previously Undescribed Clotting Factor

1952 • 89 citations

Gamma G4-Globulin Antibody causing Inhibition of Clotting Factor VIII

1968 • 87 citations

Studies on human antihemophilic factor. Evidence for a covalently linked subunit structure.

1976 • 86 citations

IMMUNOLOGICAL DIFFERENTIATION OF THREE TYPES OF HÆMOPHILIA AND IDENTIFICATION OF SOME FEMALE CARRIERS

1970 • 85 citations

HÆMORRHAGIC DIATHESIS.

1840 • 82 citations

Subunit structure of factor VIII antigen synthesized by cultured human endothelial cells.

1975 • 81 citations

ANTI-HEMOPHILIC GLOBULIN LEVELS IN CARRIERS OF HEMOPHILIA A*

1960 • 79 citations

Separation of Sub-Units of Antihemophilic Factor (AHF) by Agarose Gel Chromatography

1972 • 74 citations

Studies on the purification of antihemophilic factor (factor VIII)

1969 • 73 citations

Carbohydrate Deficiency of the Factor VIII/von Willebrand Factor Protein in von Willebrand's Disease Variants

1976 • 71 citations

Ristocetin-Induced Thrombocytopenia: Site and Mechanism of Action

1960 • 65 citations

In vitro Abnormality of the Blood in Von Willebrand's Disease correctable by Normal Plasma

1963 • 60 citations

On a Method of Determining the Condition of Blood Coagulability for Clinical and Experimental Purposes, and on the Effect of the Administration of Calcium Salts in Haemophilia and Actual or Threatened Haemorrhage: [Preliminary Communication]

1893 • 54 citations

Purification of Antihemophilic Factor (Factor VIII) by Amino Acid Precipitation*

1964 • 51 citations

THE SPORADIC CASE OF HÆMOPHILIA A

1976 • 46 citations

ISOLATION, SUBUNIT STRUCTURE, AND PROTEOLYTIC MODIFICATION OF BOVINE FACTOR VIII*

1975 • 42 citations

EVIDENCE FOR A QUALITATIVE DEFECT IN FACTOR-VIII-RELATED ANTIGEN IN VON WILLEBRAND'S DISEASE

1974 • 40 citations

The Laboratory Diagnosis of the Carrier State for Classic Hemophilia

1977 • 39 citations

Diagnosis of von Willebrand's disease

1976 • 39 citations

Double-Blind Studies on the Use of Steroids in the Treatment of Acute Hemarthrosis in Patients with Hemophilia

1970 • 39 citations

Immunologic evidence that the properties of human antihemophilic factor (factor VIII) are attributes of a single molecular species

1976 • 37 citations

The Presence of a Circulating Anti-Coagulant in a Male Member of a Hemophiliac Family.

1941 • 33 citations

ELECTROPHORETIC ISOLATION OF A CIRCULATING ANTICOAGULANT

1946 • 32 citations

Evidence that functional subunits of antihemophilic factor (Factor VIII) are linked by noncovalent bonds

1976 • 31 citations

Some Effects of Calcium on the Activation of Human Factor VIII/Von Willebrand Factor Protein by Thrombin

1977 • 30 citations

TREATMENT OF HÆMOPHILIA (FACTOR-VIII DEFICIENCY) WITH HUMAN ANTIHÆMOPHILIC FACTOR PREPARED BY THE CRYOPRECIPITATE PROCESS

1967 • 30 citations

The Use of Human Anti-haemophiiic Globulin (Fraction I-O) in Haemophilia A and in von Willebrand’s Disease

1960 • 27 citations

Separation of human factor VIII activity from the von willebrand's antigen and ristocetin platelet aggregating activity

1974 • 25 citations

Heterogeneity of human circulating anticoagulants against antihemophilic factor (factor VIII)

1975 • 24 citations

Detection of Carriers of Haemophilia

1973 • 23 citations

THE STABILITY OF ANTIHEMOPHILIC GLOBULIN AND LABILE FACTOR IN HUMAN BLOOD.

1964 • 18 citations

An account of an hemorrhagic disposition existing in certain families

1951 • 18 citations

Quantitative Determination of Factor‐VIII Protein by Two‐Stage Gel Electrophoresis

1976 • 17 citations

Immunologic evidence that the antihemophilic factor (factor VIII)-like material in hemophilic plasma possesses a nonfunctional low molecular weight subcomponent

1977 • 17 citations

Carrier Detection in Classic Hemophilia by Combined Measurement of Immunologic (VIII AGN) and Procoagulant (VIII AHF) Activities

1976 • 17 citations

Techniques for demonstration of the specificity of circulating anticoagulants against antihemophilic factor (factor VIII), with studies of two cases possibly related to diphenylhydantoin therapy

1977 • 13 citations

Antihemophilic globulin levels in carriers of hemophilia A

1961 • 10 citations

Carrier detection in classical hemophilia.

1976 • 8 citations

Abnormal parachloromercuriphenylsulfonate-sensitive cation channel in the erythrocytes of hereditary spherocytosis

1976 • 3 citations