Distinct patterns of deletion on 10p and 10q suggest involvement of multiple tumor suppressor genes in the development of astrocytic gliomas of different malignancy grades

PTEN , a Putative Protein Tyrosine Phosphatase Gene Mutated in Human Brain, Breast, and Prostate Cancer

1997 • 4,753 citations

A comprehensive genetic map of the human genome based on 5,264 microsatellites

1996 • 2,983 citations

Identification of a candidate tumour suppressor gene, MMAC1, at chromosome 10q23.3 that is mutated in multiple advanced cancers

1997 • 2,746 citations

An STS-Based Map of the Human Genome

1995 • 782 citations

Frequency of homozygous deletion at p16/CDKN2 in primary human tumours

1995 • 653 citations

Influence of location and extent of surgical resection on survival of patients with glioblastoma multiforme: Results of three consecutive radiation therapy oncology group (RTOG) clinical trials

1993 • 527 citations

Clonal genomic alterations in glioma malignancy stages.

1988 • 520 citations

Human glioblastomas with no alterations of the CDKN2A (p16INK4A, MTS1) and CDK4 genes have frequent mutations of the retinoblastoma gene.

1996 • 267 citations

Association of epidermal growth factor receptor gene amplification with loss of chromosome 10 in human glioblastoma multiforme

1992 • 215 citations

Chromosome 10 deletion mapping in human gliomas: a common deletion region in 10q25.

1995 • 184 citations

Allelotype of human malignant astrocytoma.

1990 • 163 citations

Loss of heterozygosity in malignant gliomas involves at least three distinct regions on chromosome 10

1993 • 138 citations

Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo‐astrocytomas

1992 • 117 citations

Loss of heterozygosity for 10q loci in human gliomas

1992 • 115 citations

Deletion mapping of the long arm of chromosome 10 in glioblastoma multiforme

1993 • 110 citations

Loss of heterozygosity on chromosome 10 in human glioblastoma multiforme

1989 • 109 citations

Two tumor suppressive loci on chromosome 10 involved in human glioblastomas

1995 • 86 citations

Deletion mapping of gliomas suggest the presence of two small regions for candidate tumor-suppressor genes in a 17-cM interval on chromosome 10q.

1996 • 78 citations

Analysis of the functional role of chromosome 10 loss in human glioblastomas.

1993 • 76 citations

Infrequent methylation of CDKN2A(MTS1/p16) and rare mutation of both CDKN2A and CDKN2B(MTS2/p15) in primary astrocytic tumours

1997 • 72 citations

Loss of Heterozygosity of Chromosome 10p in Human Gliomas

1996 • 51 citations

Deletion Mapping of Chromosome 10 in Human Glioma

1996 • 37 citations

Accumulation of allelic losses on chromosome 10 in human gliomas at recurrence

1996 • 8 citations